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Itaru Hamachi

Itaru Hamachi

D-Index & Metrics

Chemistry

D-Index
84
Citations
22294
World Ranking
2857
National Ranking
164

Overview

Itaru Hamachi is a researcher affiliated with Kyoto University in Japan, with a focus on biochemistry, genetics, and molecular biology. Their published work spans several areas within chemistry and molecular biology, totaling over 100 publications in these main fields. The scientist's research contributions cover diverse subfields, including molecular biology, organic chemistry, cell biology, cellular and molecular neuroscience, and biomaterials.

Their research topics often explore specialized areas such as click chemistry and applications, biotin and related studies, chemical synthesis and analysis, receptor mechanisms and signaling, supramolecular self-assembly in materials, neuroscience and neuropharmacology research, and lipid membrane structure and behavior.

Among their recent papers are:

  • Chemical Tools for Endogenous Protein Labeling and Profiling, 2020, Cell Chemical Biology
  • Organelle membrane-specific chemical labeling and dynamic imaging in living cells, 2020, Nature Chemical Biology
  • Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper, 2020, Journal of the American Chemical Society
  • Protein-responsive protein release of supramolecular/polymer hydrogel composite integrating enzyme activation systems, 2020, Nature Communications
  • Microscopic Imaging Techniques for Molecular Assemblies: Electron, Atomic Force, and Confocal Microscopies, 2021, Chemical Reviews

Frequent co-authors contributing to collaborative research efforts with Hamachi include Tomonori Tamura, Shigeki Kiyonaka, Hiroshi Nonaka, Seiji Sakamoto, and Ryou Kubota.

Their work has been published regularly in reputable scientific venues, including:

  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Biophysical Journal
  • Nature Chemical Biology

Best Publications

  • Semi-wet peptide/protein array using supramolecular hydrogel

    Shigeki Kiyonaka;Kazuki Sada;Ibuki Yoshimura;Seiji Shinkai

  • Installing logic-gate responses to a variety of biological substances in supramolecular hydrogel–enzyme hybrids

    Masato Ikeda;Tatsuya Tanida;Tatsuyuki Yoshii;Kazuya Kurotani

  • Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

    Shigeki Kiyonaka;Kenta Kato;Motohiro Nishida;Kazuhiro Mio

  • First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution.

    Akio Ojida;Yasuko Mito-Oka;Masa Aki Inoue;Itaru Hamachi

  • Molecular recognition and fluorescence sensing of monophosphorylated peptides in aqueous solution by bis(zinc(II)-dipicolylamine)-based artificial receptors.

    Akio Ojida;Yasuko Mito-oka;Kazuki Sada;Itaru Hamachi

  • Ligand-directed tosyl chemistry for protein labeling in vivo

    Shinya Tsukiji;Masayoshi Miyagawa;Yousuke Takaoka;Tomonori Tamura

  • First Thermally Responsive Supramolecular Polymer Based on Glycosylated Amino Acid

    Shigeki Kiyonaka;Kazunori Sugiyasu;Seiji Shinkai;Itaru Hamachi

  • Molecular recognition, fluorescence sensing, and biological assay of phosphate anion derivatives using artificial Zn(II)–Dpa complexes

    Takashi Sakamoto;Akio Ojida;Itaru Hamachi

  • Turn-on fluorescence sensing of nucleoside polyphosphates using a xanthene-based Zn(II) complex chemosensor

    Akio Ojida;Ippei Takashima;Takahiro Kohira;Hiroshi Nonaka

  • Protein organic chemistry and applications for labeling and engineering in live-cell systems.

    Yousuke Takaoka;Akio Ojida;Itaru Hamachi

  • Supramolecular Hydrogel Exhibiting Four Basic Logic Gate Functions To Fine-Tune Substance Release

    Harunobu Komatsu;Shinji Matsumoto;Shun ichi Tamaru;Kenji Kaneko

  • Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems

    Tomonori Tamura;Itaru Hamachi

  • Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells

    Shigeki Kiyonaka;Taketoshi Kajimoto;Reiko Sakaguchi;Daisuke Shinmi

  • Ligand-directed acyl imidazole chemistry for labeling of membrane-bound proteins on live cells

    Sho Hei Fujishima;Ryosuke Yasui;Takayuki Miki;Akio Ojida

  • Development of Highly Sensitive Fluorescent Probes for Detection of Intracellular Copper(I) in Living Systems

    Masayasu Taki;Shohei Iyoshi;Akio Ojida;Itaru Hamachi

  • Rational design of FRET-based ratiometric chemosensors for in vitro and in cell fluorescence analyses of nucleoside polyphosphates.

    Yasutaka Kurishita;Takahiro Kohira;Akio Ojida;Itaru Hamachi

  • Design Strategies of Stimuli-Responsive Supramolecular Hydrogels Relying on Structural Analyses and Cell-Mimicking Approaches

    Hajime Shigemitsu;Itaru Hamachi

  • Photo Gel-Sol/Sol-Gel Transition and Its Patterning of a Supramolecular Hydrogel as Stimuli-Responsive Biomaterials

    Shinji Matsumoto;Satoshi Yamaguchi;Shiori Ueno;Harunobu Komatsu

  • In situ real-time imaging of self-sorted supramolecular nanofibres

    Shoji Onogi;Hajime Shigemitsu;Tatsuyuki Yoshii;Tatsuya Tanida

  • Self-assembling nanoprobes that display off/on 19F nuclear magnetic resonance signals for protein detection and imaging.

    Yousuke Takaoka;Takashi Sakamoto;Shinya Tsukiji;Michiko Narazaki

  • Specific Cell Surface Protein Imaging by Extended Self-Assembling Fluorescent Turn-on Nanoprobes

    Keigo Mizusawa;Yousuke Takaoka;Itaru Hamachi

  • Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide.

    Tomonori Tamura;Tsuyoshi Ueda;Taiki Goto;Taku Tsukidate

Frequent Co-Authors

Akio Ojida
Akio Ojida Kyushu University
Seiji Shinkai
Seiji Shinkai Kyushu University
Yasuo Mori
Yasuo Mori Kyoto University
Shoji Takeuchi
Shoji Takeuchi University of Tokyo
Kenji Urayama
Kenji Urayama Kyoto Institute of Technology
Kazuki Sada
Kazuki Sada Hokkaido University
Michisuke Yuzaki
Michisuke Yuzaki Keio University
Nobutaka Fujii
Nobutaka Fujii Kyoto University
Hirokazu Tamamura
Hirokazu Tamamura Tokyo Medical and Dental University
Kouhei Tsumoto
Kouhei Tsumoto University of Tokyo

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