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Biology and Biochemistry

D-Index
49
Citations
10708
World Ranking
17935
National Ranking
7340

Overview

Graeme Mardon is affiliated with Baylor College of Medicine in the United States. Their research primarily spans fields related to Biochemistry, Genetics, and Molecular Biology with a significant focus also on Immunology and Microbiology.

Their key subfields of study include Molecular Biology, Immunology, Genetics, Virology, and Neurology. These areas underpin much of their scholarly output and highlight a diverse approach to biological and biomedical research.

The main topics covered in their work have included:

  • Retinal Development and Disorders
  • Developmental Biology and Gene Regulation
  • Single-cell and Spatial Transcriptomics
  • Invertebrate Immune Response Mechanisms
  • HIV Research and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Genomics and Phylogenetic Studies

Mardon's recent publications demonstrate a cross-section of these research areas, representing work on human genetic diversity, developmental biology in invertebrates, and immune genetics:

  • High-depth African genomes inform human migration and health (2020, Nature)
  • Single cell RNA sequencing of the adult Drosophila eye reveals distinct clusters and novel marker genes for all major cell types (2022, Communications Biology)
  • A single cell genomics atlas of the Drosophila larval eye reveals distinct photoreceptor developmental timelines (2023, Nature Communications)
  • Comprehensive single-cell atlas of the mouse retina (2024, bioRxiv [Cold Spring Harbor Laboratory])
  • Exome Sequencing Reveals a Putative Role for HLA-C*03:02 in Control of HIV-1 in African Pediatric Populations (2021, Frontiers in Genetics)

The venues where Mardon frequently publishes provide insight into the dissemination channels chosen and the audiences engaged, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Nature Communications
  • BMC Genomics
  • Research Square (Research Square)

Mardon's collaborations span several researchers who have co-authored multiple papers with them. The most frequent coauthors are:

  • Rui Chen
  • Kelvin Yeung
  • Komal Kumar Bollepogu Raja
  • Neil A. Hanchard
  • Mogomotsi Matshaba

Best Publications

  • The sex-determining region of the human Y chromosome encodes a finger protein

    David C. Page;Rebecca Mosher;Elizabeth M. Simpson;Elizabeth M.C. Fisher

  • dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila

    Graeme Mardon;Noah M. Solomon;Gerald M. Rubin

  • Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress.

    Yakov Pesah;Tuan Pham;Heather Burgess;Brooke Middlebrooks

  • Research capacity. Enabling the genomic revolution in Africa

    Charles Rotimi;Akin Abayomi;Alash'le Abimiku;Victoria May Adabayeri

  • Dachshund and Eyes Absent Proteins Form a Complex and Function Synergistically to Induce Ectopic Eye Development in Drosophila

    Rui Chen;Mehran Amoui;Zhihuan Zhang;Graeme Mardon

  • Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation

    Tiffany A. Heanue;Ram Reshef;Ram Reshef;Richard J. Davis;Graeme Mardon

  • A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase.

    Ulrike Gaul;Graeme Mardon;Gerald M. Rubin

  • Ectopic eye development in Drosophila induced by directed dachshund expression

    Weiping Shen;Graeme Mardon

  • Eyes absent represents a class of protein tyrosine phosphatases

    Jayanagendra P. Rayapureddi;Chandramohan Kattamuri;Brian D. Steinmetz;Benjamin J. Frankfort

  • High-depth African genomes inform human migration and health

    Ananyo Choudhury;Shaun Aron;Laura R. Botigué;Dhriti Sengupta

  • Isolation and characterization of two new Drosophila protein kinase C genes, including one specifically expressed in photoreceptor cells

    Eric Schaeffer;Dean P Smith;Graeme Mardon;William Quinn

  • Mutations in NMNAT1 cause Leber congenital amaurosis and identify a new disease pathway for retinal degeneration

    Robert K Koenekoop;Hui Wang;Jacek Majewski;Xia Wang

  • Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila

    Rui Chen;Georg Halder;Zhihuan Zhang;Graeme Mardon

  • The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant.

    J M Kaplan;G Mardon;J M Bishop;H E Varmus

  • The sex-determining region of the mouse Y chromosome encodes a protein with a highly acidic domain and 13 zinc fingers.

    Graeme Mardon;David C. Page

  • R8 development in the Drosophila eye: a paradigm for neural selection and differentiation.

    Benjamin J. Frankfort;Graeme Mardon

  • Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs.

    Richard J. Davis;Weiping Shen;Tiffany A. Heanue;Graeme Mardon

  • senseless Repression of rough Is Required for R8 Photoreceptor Differentiation in the Developing Drosophila Eye

    Benjamin J. Frankfort;Riitta Nolo;Riitta Nolo;Zhihuan Zhang;Hugo Bellen

  • Mutations in SPATA7 Cause Leber Congenital Amaurosis and Juvenile Retinitis Pigmentosa

    Hui Wang;Anneke I. Den Hollander;Yalda Moayedi;Abuduaini Abulimiti

  • Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality.

    Richard J. Davis;Weiping Shen;Yakov I. Sandler;Mehran Amoui

Frequent Co-Authors

Rui Chen
Rui Chen Capital Medical University
Hui Wang
Hui Wang Salk Institute for Biological Studies
James R. Lupski
James R. Lupski Baylor College of Medicine
Richard A. Lewis
Richard A. Lewis Baylor College of Medicine
Richard A. Gibbs
Richard A. Gibbs Baylor College of Medicine
Robert K. Koenekoop
Robert K. Koenekoop McGill University Health Centre
Moses Joloba
Moses Joloba Makerere University
David S. Williams
David S. Williams University of California, Los Angeles
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute

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