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Thomas Simmet

Thomas Simmet

D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
24228
World Ranking
8067
National Ranking
593

Overview

Thomas Simmet is affiliated with the University of Ulm in Germany and has contributed extensively to research in medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields, including molecular biology, pharmacology, complementary and alternative medicine, immunology, and materials chemistry.

The scientist's research covers a diverse range of topics. These include:

  • Pharmacological Effects of Medicinal Plants
  • Complementary and Alternative Medicine Studies
  • Natural product bioactivities and synthesis
  • Synthesis of Organic Compounds
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Herbal Medicine Research Studies

Simmet has published in several frequent venues, notably:

  • Biomedicine & Pharmacotherapy
  • BMC Complementary Medicine and Therapies
  • The Cambridge Structural Database
  • Molecules
  • Phytomedicine

Recent notable papers include:

  • "Complementary medicine in Germany: a multi-centre cross-sectional survey on the usage by and the needs of patients hospitalized in university medical centers," 2021, BMC Complementary Medicine and Therapies
  • "Chrysosplenol d, a Flavonol from Artemisia annua, Induces ERK1/2-Mediated Apoptosis in Triple Negative Human Breast Cancer Cells," 2020, International Journal of Molecular Sciences
  • "11-Keto-α-Boswellic Acid, a Novel Triterpenoid from Boswellia spp. with Chemotaxonomic Potential and Antitumor Activity against Triple-Negative Breast Cancer Cells," 2021, Molecules
  • "A comparative study on root and bark extracts of Eleutherococcus senticosus and their effects on human macrophages," 2020, Phytomedicine
  • "Synthesis and evaluation of antitumor activity of 9-methoxy-1H-benzo[f]chromene derivatives," 2021, Bioorganic Chemistry

Frequent coauthors working alongside Simmet include:

  • Tatiana Syrovets
  • Michael Schmiech
  • Menna El Gaafary
  • Judith Ulrich
  • Abdelaaty Hamed

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

    Amna Abderrazak;Tatiana Syrovets;Dominique Couchie;Khadija El Hadri

  • Differential Uptake of Functionalized Polystyrene Nanoparticles by Human Macrophages and a Monocytic Cell Line

    Oleg Lunov;Tatiana Syrovets;Cornelia Loos;Johanna Beil

  • Interleukin 21–Induced Granzyme B–Expressing B Cells Infiltrate Tumors and Regulate T Cells

    S. Lindner;K. Dahlke;K. Sontheimer;M. Hagn

  • The thioredoxin system as a therapeutic target in human health and disease

    Dler Faieeq Darweesh Mahmood;Amna Abderrazak;Khadija El Hadri;Thomas Simmet

  • PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation.

    Ninel Azoitei;Alexander Becher;Konrad Steinestel;Arefeh Rouhi

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

    Oleg Lunov;Tatiana Syrovets;Cornelia Loos;G. Ulrich Nienhaus;G. Ulrich Nienhaus

  • Skin Levels of Arachidonic Acid-Derived Inflammatory Mediators and Histamine in Atopic Dermatitis and Psoriasis

    Thomas Ruzicka;Thomas Simmet;Bernhard A. Peskar;Johannes Ring

  • Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIalpha.

    Tatiana Syrovets;Berthold Büchele;Erk Gedig;Joseph R. Slupsky

  • Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells

    Renato Colognato;Joseph R. Slupsky;Marina Jendrach;Ladislav Burysek

  • Functionalized polystyrene nanoparticles as a platform for studying bio–nano interactions

    C. Loos;T. Syrovets;Anna Musyanovych;Volker Mailänder

  • Plasmin as a proinflammatory cell activator

    Tatiana Syrovets;Oleg Lunov;Thomas Simmet

  • Acetyl-Boswellic Acids Inhibit Lipopolysaccharide-Mediated TNF-α Induction in Monocytes by Direct Interaction with IκB Kinases

    Tatiana Syrovets;Berthold Büchele;Christine Krauss;Yves Laumonnier

  • The serine protease plasmin triggers expression of MCP-1 and CD40 in human primary monocytes via activation of p38 MAPK and janus kinase (JAK)/STAT signaling pathways.

    Ladislav Burysek;Tatiana Syrovets;Thomas Simmet

  • Antiinflammatory and Antiatherogenic Effects of the NF-κB Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE−/− Mice

    Clarisse Cuaz-Pérolin;Ludivine Billiet;Eric Baugé;Corinne Copin

  • Inhibition of IκB Kinase Activity by Acetyl-boswellic Acids Promotes Apoptosis in Androgen-independent PC-3 Prostate Cancer Cells in Vitro and in Vivo

    Tatiana Syrovets;Jürgen E. Gschwend;Berthold Büchele;Yves Laumonnier

  • Targeting XIAP Bypasses Bcl-2–Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

    Meike Vogler;Henning Walczak;Dominic Stadel;Tobias L. Haas

  • Plasmin-induced expression of cytokines and tissue factor in human monocytes involves AP-1 and IKKbeta-mediated NF-kappaB activation.

    Tatiana Syrovets;Marina Jendrach;Marina Jendrach;Angela Rohwedder;Angela Rohwedder;Almut Schüle;Almut Schüle

Frequent Co-Authors

Hubert Schrezenmeier
Hubert Schrezenmeier University of Ulm
G. Ulrich Nienhaus
G. Ulrich Nienhaus Karlsruhe Institute of Technology
Volker Mailänder
Volker Mailänder Max Planck Society
Katharina Landfester
Katharina Landfester Max Planck Institute for Polymer Research
Thomas F. E. Barth
Thomas F. E. Barth University of Ulm
Tanja Weil
Tanja Weil Max Planck Society
Meinrad Gawaz
Meinrad Gawaz University of Tübingen
Klaus-Michael Debatin
Klaus-Michael Debatin University of Ulm
Daniel Ricklin
Daniel Ricklin University of Basel
Simone Fulda
Simone Fulda Goethe University Frankfurt

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