Giuseppe Rotilio spends much of his time researching Biochemistry, Superoxide dismutase, Cell biology, Glutathione and Copper. His Biochemistry research incorporates themes from Cancer cell and Molecular biology. The concepts of his Superoxide dismutase study are interwoven with issues in Inorganic chemistry, Electron paramagnetic resonance and Superoxide.
His Cell biology study incorporates themes from Amyotrophic lateral sclerosis and Neurodegeneration. His research investigates the connection with Glutathione and areas like Intracellular which intersect with concerns in Virus, Thioredoxin, Buthionine sulfoximine, Extracellular and Programmed cell death. Giuseppe Rotilio has included themes like Zinc, Metallothionein, Metal and Nuclear chemistry in his Copper study.
The scientist’s investigation covers issues in Superoxide dismutase, Biochemistry, Copper, Enzyme and Inorganic chemistry. His Superoxide dismutase research incorporates elements of Crystallography, Zinc, Superoxide and Active site. As part of his studies on Biochemistry, Giuseppe Rotilio often connects relevant subjects like Molecular biology.
Giuseppe Rotilio focuses mostly in the field of Copper, narrowing it down to matters related to Electron paramagnetic resonance and, in some cases, Cobalt and Titration. In his study, Cell culture is inextricably linked to Intracellular, which falls within the broad field of Glutathione. He studied Reactive oxygen species and Oxidative stress that intersect with Neurodegeneration.
Giuseppe Rotilio mainly focuses on Biochemistry, Cell biology, Oxidative stress, Apoptosis and Reactive oxygen species. The Biochemistry study combines topics in areas such as Redox and Copper. His Cell biology research focuses on SH-SY5Y and how it connects with Viability assay, Copper toxicity, Toxicity and Pyruvate dehydrogenase complex.
His Oxidative stress research is multidisciplinary, incorporating elements of Tetrahydrobiopterin, Neurodegeneration, Disease and Antioxidant. His Apoptosis research is multidisciplinary, relying on both Schiff base, Molecular biology and AMPK. His Superoxide dismutase study results in a more complete grasp of Enzyme.
His scientific interests lie mostly in Biochemistry, Cell biology, Oxidative stress, Apoptosis and Mitochondrion. His research in Biochemistry is mostly focused on Glutathione. His Cell biology study combines topics in areas such as Autophagy, Transcription factor and Cysteine.
His research integrates issues of Inflammation, Nitric oxide and Antioxidant in his study of Oxidative stress. His Apoptosis research includes themes of Cancer cell, Schiff base, Stereochemistry, Reactive oxygen species and Biological activity. His research investigates the connection between Mitochondrion and topics such as Neurodegeneration that intersect with issues in Amyotrophic lateral sclerosis, Mutation, SOD1, Organelle and Superoxide dismutase.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Aspects of the structure, function, and applications of superoxide dismutase
Joe V. Bannister;William H. Bannister;Giuseppe Rotilio.
CRC Critical Reviews in Biochemistry (1987)
Reduction and inactivation of superoxide dismutase by hydrogen peroxide
Robert C. Bray;Stephen A. Cockle;E. Martin Fielden;Peter B. Roberts.
Biochemical Journal (1974)
Cell signalling and the glutathione redox system.
Giuseppe Filomeni;Giuseppe Rotilio;Maria Rosa Ciriolo.
Biochemical Pharmacology (2002)
The mechanism of action of superoxide dismutase from pulse radiolysis and electron paramagnetic resonance. Evidence that only half the active sites function in catalysis
E. Martin Fielden;Peter B. Roberts;Robert C. Bray;David J. Lowe.
Biochemical Journal (1974)
Rescue of cells from apoptosis by inhibition of active GSH extrusion
L. Ghibelli;C. Fanelli;G. Rotilio;E. Lafavia.
The FASEB Journal (1998)
Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) and Sirtuin 1 (SIRT1) Reside in Mitochondria: POSSIBLE DIRECT FUNCTION IN MITOCHONDRIAL BIOGENESIS*
Katia Aquilano;Paola Vigilanza;Sara Baldelli;Beatrice Pagliei.
Journal of Biological Chemistry (2010)
Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells
Maria Teresa Carrì;Alberto Ferri;Andrea Battistoni;Laila Famhy.
FEBS Letters (1997)
Reactive Oxygen Species-dependent c-Jun NH2-terminal Kinase/c-Jun Signaling Cascade Mediates Neuroblastoma Cell Death Induced by Diallyl Disulfide
Giuseppe Filomeni;Katia Aquilano;Giuseppe Rotilio;Maria R. Ciriolo.
Cancer Research (2003)
Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols
Katia Aquilano;Sara Baldelli;Giuseppe Rotilio;Maria Rosa Ciriolo.
Neurochemical Research (2008)
Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials
Alberto Ferri;Mauro Cozzolino;Claudia Crosio;Monica Nencini.
Proceedings of the National Academy of Sciences of the United States of America (2006)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
University of Rome Tor Vergata
University of Rome Tor Vergata
Sapienza University of Rome
University of Milan
University of Rome Tor Vergata
University of Rome Tor Vergata
Exiris
University of Tübingen
Sapienza University of Rome
Sapienza University of Rome
University of Klagenfurt
Loughborough University
University of Calabria
Purdue University West Lafayette
Purchase College
Kyoto Pharmaceutical University
University of Science and Technology of China
University of Missouri
University of Manchester
Institut de Recherche pour le Développement
Federal University of Rio de Janeiro
Osaka University
Yale University
Technical University of Denmark
University of Illinois at Chicago
Yale University