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George N. Tzanakakis

George N. Tzanakakis

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
10037
World Ranking
13382
National Ranking
28

Overview

George N. Tzanakakis is affiliated with the University of Crete in Greece and contributes to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans molecular biology, cell biology, oncology, immunology and allergy, as well as pulmonary and respiratory medicine.

The scientist's main research topics include proteoglycans and glycosaminoglycans research, glycosylation and glycoproteins research, fibroblast growth factor research, cancer cells and metastasis, cell adhesion molecules research, TGF-β signaling in diseases, and sarcoma diagnosis and treatment.

Frequent publication venues for their research are Cancers, Biomolecules, Molecular Pharmaceutics, International Journal of Oncology, and Frontiers in Medicine.

Recent papers authored or co-authored by George N. Tzanakakis include:

  • Proteoglycans in the Pathogenesis of Hormone-Dependent Cancers: Mediators and Effectors, 2020, Cancers
  • The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis, 2021, Cancers
  • Lumican in Carcinogenesis-Revisited, 2021, Biomolecules
  • Glycosaminoglycans: Carriers and Targets for Tailored Anti-Cancer Therapy, 2021, Biomolecules
  • Assessment of Amphiphilic Poly-N-vinylpyrrolidone Nanoparticles' Biocompatibility with Endothelial Cells in Vitro and Delivery of an Anti-Inflammatory Drug, 2020, Molecular Pharmaceutics

Collaborations are evident with frequent co-authors including Dragana Nikitovic, Aikaterini Berdiaki, Eirini-Maria Giatagana, Aristidis Tsatsakis, and Monica Neagu.

Best Publications

  • Lead toxicity update. A brief review.

    Nikolas C Papanikolaou;Eleftheria G Hatzidaki;Stamatis Belivanis;George N Tzanakakis

  • Glycosaminoglycans: key players in cancer cell biology and treatment

    Nikos Afratis;Chrisostomi Gialeli;Dragana Nikitovic;Theodore Tsegenidis

  • Anticancer and apoptosis‑inducing effects of quercetin in vitro and in vivo

    Mahmoud Hashemzaei;Amin Delarami Far;Arezoo Yari;Reza Entezari Heravi

  • Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting.

    Achilleas D. Theocharis;Spyridon S. Skandalis;George N. Tzanakakis;Nikos K. Karamanos

  • Cross-talk between estradiol receptor and EGFR/IGF-IR signaling pathways in estrogen-responsive breast cancers: focus on the role and impact of proteoglycans.

    Spyros S. Skandalis;Nikolaos Afratis;Gianna Smirlaki;Dragana Nikitovic

  • Occupational and environmental exposure to pesticides and cytokine pathways in chronic diseases (Review).

    Silvia Gangemi;Eliza Gofita;Chiara Costa;Michele Teodoro

  • Lumican, a small leucine-rich proteoglycan.

    Dragana Nikitovic;Paulos Katonis;Aristidis Tsatsakis;Nikos K. Karamanos

  • Human papilloma virus: Apprehending the link with carcinogenesis and unveiling new research avenues (Review).

    Daniel Boda;Anca Oana Docea;Daniela Calina;Mihaela Adriana Ilie

  • The Biology of Small Leucine-rich Proteoglycans in Bone Pathophysiology

    Dragana Nikitovic;John Aggelidakis;Marian F. Young;Renato V. Iozzo

  • The impact of zoledronic acid therapy in survival of lung cancer patients with bone metastasis.

    Kostantinos Zarogoulidis;Eufimia Boutsikou;Pavlos Zarogoulidis;Ellada Eleftheriadou

  • Role of receptor for hyaluronic acid-mediated motility (RHAMM) in low molecular weight hyaluronan (LMWHA)-mediated fibrosarcoma cell adhesion.

    Katerina Kouvidi;Aikaterini Berdiaki;Dragana Nikitovic;Pavlos Katonis

  • Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate

    Nikos K. Karamanos;Peter Vanky;George N. Tzanakakis;Theodore Tsegenidis

  • Anticarcinogenic activity of polyphenolic extracts from grape stems against breast, colon, renal and thyroid cancer cells.

    Despina Sahpazidou;George D. Geromichalos;Dimitrios Stagos;Anna Apostolou

  • Inflammation and Metabolism in Cancer Cell-Mitochondria Key Player.

    Monica Neagu;Carolina Constantin;Iulia Dana Popescu;Donato Zipeto

  • Cancer microenvironment and inflammation: role of hyaluronan.

    Dragana Nikitovic;Maria Tzardi;Aikaterini Berdiaki;Aristidis Tsatsakis

  • Lumican affects tumor cell functions, tumor–ECM interactions, angiogenesis and inflammatory response

    Dragana Nikitovic;Antonis Papoutsidakis;Nikos K. Karamanos;George N. Tzanakakis

  • The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents.

    Athanasia P Asimakopoulou;Achilleas D Theocharis;George N Tzanakakis;Nikos K Karamanos

  • A study of zearalenone cytotoxicity on human peripheral blood mononuclear cells.

    Zaxarenia Vlata;Filippos Porichis;George Tzanakakis;Aristidis Tsatsakis

  • Determination of hyaluronan and galactosaminoglycan disaccharides by high-performance capillary electrophoresis at the attomole level. Applications to analyses of tissue and cell culture proteoglycans

    Nikos K. Karamanos;Susanna Axelsson;Peter Vanky;George N. Tzanakakis

  • Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells

    Dragana Nikitovic;Aikaterini Berdiaki;Alexandros Zafiropoulos;Pavlos Katonis

Frequent Co-Authors

Nikos K. Karamanos
Nikos K. Karamanos University of Patras
Aristidis Tsatsakis
Aristidis Tsatsakis University of Crete
Demetrios A. Spandidos
Demetrios A. Spandidos University of Crete
Achilleas D. Theocharis
Achilleas D. Theocharis University of Patras
Dimitris Kletsas
Dimitris Kletsas National Centre of Scientific Research Demokritos
Emanuela Corsini
Emanuela Corsini University of Milan
Daniela Calina
Daniela Calina University of Medicine and Pharmacy of Craiova
Paraskevi Heldin
Paraskevi Heldin Uppsala University
Alberto Passi
Alberto Passi University of Insubria
Vincent C. Hascall
Vincent C. Hascall Cleveland Clinic

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