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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10437
World Ranking
13961
National Ranking
5897

Overview

Gary Brewer is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, Brewer has contributed extensively to subfields including Molecular Biology, Cardiology and Cardiovascular Medicine, Infectious Diseases, Pulmonary and Respiratory Medicine, and Oncology.

Their research interests focus on topics related to viral infections and immunology, RNA and protein synthesis mechanisms, RNA research and splicing, viral gastroenteritis research and epidemiology, RNA regulation and disease, SARS-CoV-2 and COVID-19 research, and infection control and ventilation.

Brewer has coauthored frequently with several researchers, including:

  • Blanton S. Tolbert
  • Mei-Ling Li
  • Amanda E. Hargrove
  • Jesse Davila-Calderon
  • Christina Haddad

Their publications have appeared predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The FASEB Journal
  • Science Advances
  • Journal of Biological Chemistry
  • Methods

Notable recent papers by Brewer include:

  • "IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex," 2020, Nature Communications
  • "Enterovirus A71 Vaccines," 2021, Vaccines
  • "Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures," 2021, Science Advances
  • "Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Impact of sampling and storage stress on the recovery of airborne SARS-CoV-2 virus surrogate captured by filtration," 2021, Journal of Occupational and Environmental Hygiene

In addition to journal articles, Brewer has contributed to book publications. One such publication is "RNA-based Mechanisms in Cancer" released in 2021 by World Scientific.

Best Publications

  • Regulation of mRNA stability in mammalian cells

    Jayita Guhaniyogi;Gary Brewer

  • Control of mRNA Decay by Heat Shock-Ubiquitin-Proteasome Pathway

    Gaurav Laroia;Rafael Cuesta;Gary Brewer;Robert J. Schneider

  • Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascade

    Marina Lasa;Kamal R. Mahtani;Andrew Finch;Gary Brewer

  • The regulation of mRNA stability in mammalian cells: 2.0.

    Xiangyue Wu;Gary Brewer

  • The role of AUF1 in regulated mRNA decay.

    Frances M. Gratacós;Gary Brewer

  • Identification of AUF1 (heterogeneous nuclear ribonucleoprotein D) as a component of the alpha-globin mRNA stability complex.

    Megerditch Kiledjian;Christine T. Demaria;Gary Brewer;Kristine Novick

  • Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover.

    Shankung Lin;Wengong Wang;Gerald M. Wilson;Xiaoling Yang

  • Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1

    Gerald M. Wilson;Jiebo Lu;Kristina Sutphen;Yue Sun

  • Characteristics of the Interaction of a Synthetic Human Tristetraprolin Tandem Zinc Finger Peptide with AU-rich Element-containing RNA Substrates

    Perry J. Blackshear;Wi S. Lai;Elizabeth A. Kennington;Gary Brewer

  • Interleukin-17 enhances immunosuppression by mesenchymal stem cells

    X Han;Q Yang;L Lin;C Xu

  • MicroRNA degradation and turnover: regulating the regulators

    Zhuo Zhang;Yong-Wen Qin;Gary Brewer;Gary Brewer;Qing Jing

  • Phosphorylation of p40AUF1 regulates binding to A + U-rich mRNA-destabilizing elements and protein-induced changes in ribonucleoprotein structure.

    Gerald M. Wilson;Jiebo Lu;Kristina Sutphen;Yvelisse Suarez

  • Properties of the exonuclease activity that degrades H4 histone mRNA

    J Ross;G Kobs;G Brewer;S W Peltz

  • Lactate dehydrogenase is an AU-rich element-binding protein that directly interacts with AUF1.

    Patricia A. Pioli;B. JoNell Hamilton;John E. Connolly;Gary Brewer

  • Posttranscriptional Derepression of GADD45α by Genotoxic Stress

    Ashish Lal;Kotb Abdelmohsen;Rudolf Pullmann;Tomoko Kawai

  • miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2.

    Chunliang Xu;Guangwen Ren;Guangwen Ren;Gang Cao;Qing Chen

  • Regulation of the Epstein-Barr Virus C Promoter by AUF1 and the Cyclic AMP/Protein Kinase A Signaling Pathway

    Ezequiel M. Fuentes-Pananá;RongSheng Peng;Gary Brewer;Jie Tan

  • Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay

    Kristina S. Sinsimer;Frances M. Gratacós;Anna M. Knapinska;Jiebo Lu

  • Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.

    Anna M. Knapinska;Frances M. Gratacós;Christopher D. Krause;Kristina Hernandez

  • Increased interleukin-10 mRNA stability in melanoma cells is associated with decreased levels of A + U-rich element binding factor AUF1.

    Gary Brewer;Simona Saccani;Srijata Sarkar;Anita Lewis

Frequent Co-Authors

Shin-Ru Shih
Shin-Ru Shih Chang Gung University
Sidney Pestka
Sidney Pestka Rutgers, The State University of New Jersey
Megerditch Kiledjian
Megerditch Kiledjian Rutgers, The State University of New Jersey
Arnold B. Rabson
Arnold B. Rabson Rutgers, The State University of New Jersey
Andrew R. Clark
Andrew R. Clark University of Birmingham
Jeremy Saklatvala
Jeremy Saklatvala University of Oxford
David M. Ojcius
David M. Ojcius University of the Pacific
Jen Ren Wang
Jen Ren Wang National Cheng Kung University
Robert Wang
Robert Wang Chinese Academy of Sciences
Myriam Gorospe
Myriam Gorospe National Institutes of Health

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