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Biology and Biochemistry

D-Index
56
Citations
8082
World Ranking
14704
National Ranking
1051

Overview

Freimut Schliess is affiliated with Heinrich Heine University Düsseldorf in Germany and conducts research primarily in the field of Medicine with a focus on Endocrinology, Diabetes and Metabolism. Their work spans several specialized subfields including Epidemiology, Molecular Biology, Physiology, and Cardiovascular Medicine.

The scientist's research mainly addresses topics related to diabetes management and research, diabetes treatment and management, metabolomics and mass spectrometry studies, liver disease diagnosis and treatment, chronic disease management strategies, lipid metabolism and disorders, as well as traditional Chinese medicine studies.

Freimut Schliess has contributed to multiple publications across various scientific journals. Recent papers include:

  • Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes, 2020, Diabetes
  • Costs and its drivers for diabetes mellitus type 2 patients in France and Germany: a systematic review of economic studies, 2020, BMC Health Services Research
  • TIGER: technical variation elimination for metabolomics data using ensemble learning architecture, 2021, Briefings in Bioinformatics
  • Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse, 2021, Metabolites
  • Integrated personalized diabetes management goes Europe: A multi-disciplinary approach to innovating type 2 diabetes care in Europe, 2020, Primary care diabetes

Freimut Schliess frequently collaborates with several coauthors, including Rui Wang-Sattler, Tim Heise, Jialing Huang, Cornelia Prehn, and Karsten Suhre, each contributing to multiple publications alongside the scientist.

The scientist's work has been published in notable venues such as Diabetes, BMC Health Services Research, Briefings in Bioinformatics, Metabolites, and Primary care diabetes.

Best Publications

  • Hepatic encephalopathy in chronic liver disease: a clinical manifestation of astrocyte swelling and low-grade cerebral edema?

    Dieter Häussinger;Gerald Kircheis;Richard Fischer;Freimut Schliess

  • Pathogenetic mechanisms of hepatic encephalopathy

    D Häussinger;F Schliess

  • Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes.

    Freimut Schliess;Boris Görg;Richard Fischer;Paul Desjardins

  • Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices.

    Roland Reinehr;Boris Görg;Stephan Becker;Natalia Qvartskhava

  • Congenital glutamine deficiency with glutamine synthetase mutations.

    Johannes Häberle;Boris Görg;Frank Rutsch;Eva Schmidt

  • Copper Ions Strongly Activate the Phosphoinositide-3-Kinase/Akt Pathway Independent of the Generation of Reactive Oxygen Species

    Elena A. Ostrakhovitch;Mohammad Reza Lordnejad;Freimut Schliess;Helmut Sies

  • Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

    Jan Marquard;Silke Otter;Alena Welters;Alin Stirban

  • Activation of extracellular signal-regulated kinases Erk-1 and Erk-2 by cell swelling in H4IIE hepatoma cells.

    F Schliess;R Schreiber;D Häussinger

  • Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation.

    Roland Reinehr;Freimut Schliess;Dieter Häussinger

  • Reversible inhibition of mammalian glutamine synthetase by tyrosine nitration.

    Boris Görg;Natalia Qvartskhava;Peter Voss;Tilman Grune

  • Ammonia induces RNA oxidation in cultured astrocytes and brain in vivo.

    Boris Görg;Natalia Qvartskhava;Verena Keitel;Hans J. Bidmon

  • Regulation of taurocholate excretion by a hypo-osmolarity-activated signal transduction pathway in rat liver

    B Noe;F Schliess;M Wettstein;S Heinrich

  • Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.

    F Schliess;AK Kurz;S vom Dahl;D Haussinger

  • Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis

    Dieter Häussinger;Anna Kordelia Kurz;Matthias Wettstein;Dirk Graf

  • Calcium-dependent activation of Erk-1 and Erk-2 after hypo-osmotic astrocyte swelling.

    Freimut Schliess;Ralf Sinning;Richard Fischer;Corinne Schmalenbach

  • Involvement of Integrins in Osmosensing and Signaling toward Autophagic Proteolysis in Rat Liver

    Stephan vom Dahl;Freimut Schliess;Regina Reissmann;Boris Görg

  • Involvement of p38MAPK in the regulation of proteolysis by liver cell hydration

    Dieter Häussinger;Freimut Schliess;Frank Dombrowski;Stephan Vom Dahl

  • The cellular hydration state: a critical determinant for cell death and survival.

    Freimut Schliess;Dieter Häussinger

  • Activation of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway by Osmotic Shock

    Petros Gatsios;Lara Terstegen;Freimut Schliess;Dieter Häussinger

  • Activation of JNK and p38 but not ERK MAP Kinases in Human Skin Cells by 5-Aminolevulinate-Photodynamic Therapy

    Lars-Oliver Klotz;Clemens Fritsch;Karlis Briviba;Nicolaos Tsacmacidis

Frequent Co-Authors

Dieter Häussinger
Dieter Häussinger Heinrich Heine University Düsseldorf
Ertan Mayatepek
Ertan Mayatepek Heinrich Heine University Düsseldorf
Annick Toutain
Annick Toutain François Rabelais University
Per-Olof Berggren
Per-Olof Berggren Karolinska Institute
Juris J. Meier
Juris J. Meier Ruhr University Bochum
Helmut Sies
Helmut Sies Heinrich Heine University Düsseldorf
Lars-Oliver Klotz
Lars-Oliver Klotz Friedrich Schiller University Jena
Tilman Grune
Tilman Grune University of Potsdam
Karl Zilles
Karl Zilles Forschungszentrum Jülich
Jerzy Adamski
Jerzy Adamski Helmholtz Association of German Research Centres

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