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Biology and Biochemistry

D-Index
70
Citations
20944
World Ranking
6923
National Ranking
505

Overview

Enno Hartmann is affiliated with the University of Lübeck in Germany and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research primarily focuses on Molecular Biology, with additional work in Immunology, Physiology, Cell Biology, and Rehabilitation.

Their research interests span several main topics, including RNA Research and Splicing, Nuclear Structure and Function, RNA modifications and cancer, RNA and protein synthesis mechanisms, Endoplasmic Reticulum Stress and Disease, Genomics and Chromatin Dynamics, and Pain Mechanisms and Treatments.

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Science Advances
  • Science
  • Molecular & Cellular Proteomics

Some recent papers authored or co-authored by Enno Hartmann are:

  • Importin α3 regulates chronic pain pathways in peripheral sensory neurons, 2020, Science
  • Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative, 2023, Science Advances
  • Cellular Importin-α3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection, 2020, Cell Reports
  • A Proteomic Study on the Membrane Protein Fraction of T Cells Confirms High Substrate Selectivity for the ER Translocation Inhibitor Cyclotriazadisulfonamide, 2021, Molecular & Cellular Proteomics
  • Kpna6 deficiency causes infertility in male mice by disrupting spermatogenesis, 2021, Development

Enno Hartmann has collaborated frequently with several co-authors including:

  • Franziska Rother
  • Michael Bäder
  • Becky Provinciael
  • Kurt Vermeire
  • Joren Stroobants

The scientist's work contributes to understanding the molecular mechanisms underlying RNA-related processes, cellular transport, and protein synthesis, often exploring the implications for disease states such as cancer, infertility, chronic pain, and viral infection response pathways.

Best Publications

  • X-ray structure of a protein-conducting channel

    Bert van den Berg;William M. Clemons;Ian Collinson;Yorgo Modis

  • Isolation of a protein that is essential for the first step of nuclear protein import

    Dirk Görlich;Siegfried Prehn;Ronald A. Laskey;Enno Hartmann

  • Predicting the orientation of eukaryotic membrane-spanning proteins

    Enno Hartmann;Tom A. Rapoport;Harvey F. Lodish

  • Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope.

    Dirk Görlich;Susanne Kostka;Regine Kraft;Colin Dingwall

  • Distinct functions for the two importin subunits in nuclear protein import

    Dirk Görlich;Frank Vogel;Anthony D. Mills;Enno Hartmann

  • A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

    Dirk Görlich;Siegfried Prehn;Enno Hartmann;Kai-Uwe Kalies

  • A Novel Class of RanGTP Binding Proteins

    D. Görlich;M. Dabrowski;F. R. Bischoff;U. Kutay

  • Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

    Steffen Panzner;Lars Dreier;Enno Hartmann;Susanne Kostka

  • A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus.

    D. Görlich;P. Henklein;R. A. Laskey;E. Hartmann

  • Identification of a tRNA-specific Nuclear Export Receptor

    U. Kutay;G. Lipowsky;E. Izaurralde;F. R. Bischoff

  • Complementation cloning identifies CDG-IIc, a new type of congenital disorders of glycosylation, as a GDP-fucose transporter deficiency.

    Torben Lübke;Thorsten Marquardt;Amos Etzioni;Enno Hartmann

  • A protein of the endoplasmic reticulum involved early in polypeptide translocation

    Dirk Görlich;Enno Hartmann;Siegfried Prehn;Siegfried Prehn;Tom A. Rapoport

  • Exportin 6: a novel nuclear export receptor that is specific for profilin·actin complexes

    Theis Stüven;Enno Hartmann;Dirk Görlich

  • A novel pathway for secretory proteins

    Anne Muesch;Enno Hartmann;Klaus Rohde;Anna Rubartelli

  • Evidence for Distinct Substrate Specificities of Importin α Family Members in Nuclear Protein Import

    M. Köhler;C. Speck;M. Christiansen;F. R. Bischoff

  • A class of membrane proteins with a C-terminal anchor

    Ulrike Kutay;Enno Hartmann;Tom A. Rapoport

  • Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

    Stefan Jäkel;José-Manuel Mingot;Petra Schwarzmaier;Enno Hartmann

  • Transport route for synaptobrevin via a novel pathway of insertion into the endoplasmic reticulum membrane.

    U Kutay;G Ahnert-Hilger;E Hartmann;B Wiedenmann

  • Evolutionary conservation of components of the protein translocation complex

    Enno Hartmann;Thomas Sommer;Siegfried Prehn;Dirk Görlich

  • A signal sequence receptor in the endoplasmic reticulum membrane.

    Martin Wiedmann;Teymuras V. Kurzchalia;Enno Hartmann;Tom A. Rapoport

Frequent Co-Authors

Tom A. Rapoport
Tom A. Rapoport Harvard University
Dirk Görlich
Dirk Görlich Max Planck Society
Michael Bader
Michael Bader Max Delbrück Center for Molecular Medicine
Regine Kraft
Regine Kraft Max Delbrück Center for Molecular Medicine
Teymuras V. Kurzchalia
Teymuras V. Kurzchalia Max Planck Society
Martin Wiedmann
Martin Wiedmann Cornell University
Ronald A. Laskey
Ronald A. Laskey University of Cambridge
Bernhard Dobberstein
Bernhard Dobberstein Heidelberg University
Ulrike Kutay
Ulrike Kutay ETH Zurich

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