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Biology and Biochemistry

D-Index
63
Citations
14819
World Ranking
10183
National Ranking
4448

Overview

Emmett V. Schmidt is affiliated with MSD (United States) and has developed a research portfolio primarily within the field of Medicine, with a strong focus on Oncology. Their work spans several subfields including Oncology, Immunology, Pulmonary and Respiratory Medicine, Molecular Biology, and Surgery.

The scientist's research interests center primarily on cancer-related topics. Major areas of work include Cancer Immunotherapy and Biomarkers, Pancreatic and Hepatic Oncology Research, CAR-T Cell Therapy Research, Renal Cell Carcinoma Treatment, Computational Drug Discovery Methods, Endometrial and Cervical Cancer Treatments, and Immunotherapy and Immune Responses.

Frequent coauthors collaborating with Emmett V. Schmidt include:

  • Allen Lee Cohn
  • Matthew H. Taylor
  • Marcia S. Brose
  • Corina E. Dutcus
  • Jane Wu

The scientist's publications appear most often in the following venues:

  • Journal of Clinical Oncology
  • Regular and Young Investigator Award Abstracts
  • Contemporary Clinical Trials
  • Journal for ImmunoTherapy of Cancer
  • The Lancet Oncology

Notable recent papers published by Emmett V. Schmidt include:

  • Lenvatinib Plus Pembrolizumab in Patients With Advanced Endometrial Cancer, 2020, Journal of Clinical Oncology
  • Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study, 2021, The Lancet Oncology
  • Drug independence and the curability of cancer by combination chemotherapy, 2022, Trends in cancer
  • MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses, 2020, Science
  • Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti-PD-(L)1 Therapy, 2020, Clinical Cancer Research

Best Publications

  • Mammary Hyperplasia and Carcinoma in MMTV-cyclin D1 Transgenic Mice

    Timothy C. Wang;Robert D. Cardiff;Lawrence Zukerberg;Emma Lees

  • IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development

    Yixue Cao;Giuseppina Bonizzi;Tiffany N. Seagroves;Florian R. Greten

  • The role of c-myc in cellular growth control.

    Emmett V Schmidt

  • Lenvatinib plus pembrolizumab in patients with advanced endometrial cancer: an interim analysis of a multicentre, open-label, single-arm, phase 2 trial.

    Vicky Makker;Drew Rasco;Nicholas J Vogelzang;Marcia S Brose

  • Lenvatinib Plus Pembrolizumab in Patients With Advanced Endometrial Cancer

    Vicky Makker;Matthew H. Taylor;Carol Aghajanian;Ana Oaknin

  • Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

    I B Rosenwald;A Lazaris-Karatzas;N Sonenberg;E V Schmidt

  • Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

    Igor B. Rosenwald;David B. Rhoads;Lawrence D. Callanan;Kurt J. Isselbacher

  • Eukaryotic Translation Initiation Factor 4E Regulates Expression of Cyclin D1 at Transcriptional and Post-transcriptional Levels

    Igor B. Rosenwald;Roger Kaspar;Dennis Rousseau;Lee Gehrke

  • Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells.

    Goshi Shiota;David B. Rhoads;Timothy C. Wang;Toshikazu Nakamura

  • SD-101 in Combination with Pembrolizumab in Advanced Melanoma: Results of a Phase Ib, Multicenter Study

    Antoni Ribas;Theresa Medina;Shivaani Kummar;Asim Amin

  • The cytomegalovirus enhancer: a pan-active control element in transgenic mice.

    E V Schmidt;G Christoph;R Zeller;P Leder

  • Epacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037)

    Tara C Mitchell;Omid Hamid;David C Smith;Todd M Bauer

  • Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast

    Michael Polymenis;Emmett V. Schmidt

  • Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 (enkephalinase): direct evidence by cDNA transfection analysis

    Margaret A. Shipp;Jayanthi Vijayaraghavan;Emmett V. Schmidt;Emma L. Masteller

  • Viral RNA Mutations Are Region Specific and Increased by Ribavirin in a Full-Length Hepatitis C Virus Replication System

    Ana Maria Contreras;Yoichi Hiasa;Wenping He;Adam Terella

  • An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc.

    R M Jones;J Branda;K A Johnston;M Polymenis

  • Primary hyperparathyroidism caused by parathyroid-targeted overexpression of cyclin D1 in transgenic mice

    Yasuo Imanishi;Yoshitaka Hosokawa;Katsuhiko Yoshimoto;Katsuhiko Yoshimoto;Ernestina Schipani

  • The role of c-myc in regulation of translation initiation.

    Emmett V Schmidt

  • Phase Ib Study of Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Combination with Pembrolizumab (MK-3475) in Patients with Advanced Solid Tumors.

    Anthony W. Tolcher;Mario Sznol;Siwen Hu-Lieskovan;Kyriakos P. Papadopoulos

  • Hepatitis C Virus Expression Suppresses Interferon Signaling by Degrading STAT1

    Wenyu Lin;Won Hyeok Choe;Yoichi Hiasa;Yoshitaka Kamegaya

Frequent Co-Authors

Raymond T. Chung
Raymond T. Chung Harvard University
Timothy C. Wang
Timothy C. Wang Columbia University
Philip Leder
Philip Leder Harvard University
Nicholas J. Vogelzang
Nicholas J. Vogelzang University of Nevada Reno
Toshikazu Nakamura
Toshikazu Nakamura Osaka University
Antoni Ribas
Antoni Ribas University of California, Los Angeles
James W. Mier
James W. Mier Beth Israel Deaconess Medical Center
Thomas F. Gajewski
Thomas F. Gajewski University of Chicago
Dmitry I. Gabrilovich
Dmitry I. Gabrilovich AstraZeneca (United Kingdom)
Kazue Takahashi
Kazue Takahashi Harvard University

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