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D-Index & Metrics

Neuroscience

D-Index
41
Citations
15214
World Ranking
7740
National Ranking
3320

Overview

Dorothy P. Schafer is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on neuroscience and immunology, with a significant number of publications in these main fields of study. Schafer's work spans various subfields, including neurology, immunology, molecular biology, cellular and molecular neuroscience, and developmental neuroscience.

The scientist has contributed extensively to topics related to neuroinflammation and neurodegeneration mechanisms, immune cells in cancer, immune response and inflammation, neuroscience and neuropharmacology research, neurogenesis and neuroplasticity mechanisms, tryptophan and brain disorders, and interferon and immune responses.

Recent influential papers include:

  • "Microglia states and nomenclature: A field at its crossroads" (2022) published in Neuron
  • "A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis" (2021) published in Nature
  • "Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS" (2021) published in Nature Reviews Neuroscience
  • "Neuroinflammation in Alzheimer disease" (2024) published in Nature Reviews Immunology
  • "Cytokines as emerging regulators of central nervous system synapses" (2023) published in Immunity

Schafer collaborates frequently with several researchers, including Travis E. Faust, Violeta Durán-Laforet, Anne Schaefer, Amanda Sierra, and Mikael Simons. These partnerships reflect an active engagement in collaborative research efforts.

The scientist's studies have been published in prominent journals, with frequent publication venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • Nature Communications
  • Immunity
  • Cell

Best Publications

  • Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner.

    Dorothy P. Schafer;Emily K. Lehrman;Amanda G. Kautzman;Ryuta Koyama

  • Microglia states and nomenclature: A field at its crossroads

    Unknown

  • A lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis.

    Martina Absinta;Martina Absinta;Martina Absinta;Dragan Maric;Marjan Gharagozloo;Thomas Garton

  • The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS.

    Dorothy P. Schafer;Emily K. Lehrman;Beth Stevens;Beth Stevens

  • Neuronal vulnerability and multilineage diversity in multiple sclerosis

    Lucas Schirmer;Dmitry Velmeshev;Staffan Holmqvist;Max Kaufmann

  • Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease.

    Sebastian Werneburg;Jonathan Jung;Rejani B. Kunjamma;Seung Kwon Ha

  • Microglia Function in Central Nervous System Development and Plasticity

    Dorothy P. Schafer;Beth Stevens

  • Removable cranial windows for long-term imaging in awake mice

    Glenn J Goldey;Demetris K Roumis;Lindsey L Glickfeld;Aaron M Kerlin

  • Microglia: Architects of the Developing Nervous System

    Jeffrey L. Frost;Dorothy P. Schafer

  • Mechanisms governing activity-dependent synaptic pruning in the developing mammalian CNS

    Travis E Faust;Georgia Gunner;Dorothy P Schafer

  • Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling.

    Georgia Gunner;Lucas Cheadle;Kasey M Johnson;Pinar Ayata

  • TTC, fluoro-Jade B and NeuN staining confirm evolving phases of infarction induced by middle cerebral artery occlusion.

    Fudong Liu;Dorothy P. Schafer;Louise D. McCullough;Louise D. McCullough

  • Neuroinflammation in Alzheimer disease

    Unknown

  • Neuroinflammation: Ways in Which the Immune System Affects the Brain.

    Richard M. Ransohoff;Dorothy Schafer;Angela Vincent;Nathalie E. Blachère

  • Disruption of the Axon Initial Segment Cytoskeleton Is a New Mechanism for Neuronal Injury

    Dorothy P. Schafer;Smita Jha;Fudong Liu;Trupti Akella

  • Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system.

    Dorothy P. Schafer;Beth Stevens

  • Does Paranode Formation and Maintenance Require Partitioning of Neurofascin 155 into Lipid Rafts

    Dorothy P. Schafer;Rashmi Bansal;Kristian L. Hedstrom;Steven E. Pfeiffer

  • Spectrins and AnkyrinB Constitute a Specialized Paranodal Cytoskeleton

    Yasuhiro Ogawa;Dorothy P. Schafer;Ido Horresh;Vered Bar

  • Cytokines as emerging regulators of central nervous system synapses.

    Unknown

  • Dysfunction of nodes of Ranvier: a mechanism for anti-ganglioside antibody-mediated neuropathies

    Keiichiro Susuki;Nobuhiro Yuki;Dorothy P. Schafer;Koichi Hirata

  • Synapse elimination during development and disease: immune molecules take centre stage.

    Dorothy P. Schafer;Beth Stevens

  • Microglia contribute to circuit defects in Mecp2 null mice independent of microglia-specific loss of Mecp2 expression.

    Dorothy P Schafer;Dorothy P Schafer;Christopher T Heller;Christopher T Heller;Georgia Gunner;Georgia Gunner;Molly Heller

  • A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature.

    Erica Mondo;Shannon C. Becker;Amanda G. Kautzman;Martina Schifferer

  • An engulfment assay: a protocol to assess interactions between CNS phagocytes and neurons.

    Dorothy P. Schafer;Emily K. Lehrman;Christopher T. Heller;Beth Stevens

Frequent Co-Authors

Beth Stevens
Beth Stevens Boston Children's Hospital
Matthew N. Rasband
Matthew N. Rasband Baylor College of Medicine
Richard M. Ransohoff
Richard M. Ransohoff Harvard University
Michael E. Greenberg
Michael E. Greenberg Harvard University
Louise D. McCullough
Louise D. McCullough The University of Texas Health Science Center at Houston
Martina Absinta
Martina Absinta San Raffaele Hospital
Bruce T. Lamb
Bruce T. Lamb Indiana University
Brian Popko
Brian Popko Northwestern University
Monica L. Vetter
Monica L. Vetter University of Utah
Gyongyi Szabo
Gyongyi Szabo Beth Israel Deaconess Medical Center

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