Donald P. Cain

Overview

Best Publications

• Neurobiological effects of intraventricular propionic acid in rats: possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders.

  Derrick F. MacFabe;Donald P. Cain;Karina Rodriguez-Capote;Andrew E. Franklin

  545
  Citations

• Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder.

  Derrick F. MacFabe;Nathan E. Cain;Francis Boon;Klaus-Peter Ossenkopp

  450
  Citations

• Spatial learning without NMDA receptor-dependent long-term potentiation.

  Deborah Saucier;Donald P. Cain

  430
  Citations

• Partial reversal of the effect of maternal care on cognitive function through environmental enrichment.

  T.W Bredy;R.A Humpartzoomian;D.P Cain;M.J Meaney

  337
  Citations

• Long-term potentiation and kindling: How similar are the mechanisms?

  Donald P. Cain

  251
  Citations

• Contribution of sex differences in the acute stress response to sex differences in water maze performance in the rat.

  Jason Beiko;Rebecca Lander;Elizabeth Hampson;Francis Boon

  245
  Citations

• Intracerebroventricular Injection of Propionic Acid, an Enteric Bacterial Metabolic End-Product, Impairs Social Behavior in the Rat: Implications for an Animal Model of Autism

  Sandy R. Shultz;Derrick F. MacFabe;Klaus Peter Ossenkopp;Shannon Scratch

  238
  Citations

• Detailed behavioral analysis of water maze acquisition under systemic NMDA or muscarinic antagonism: nonspatial pretraining eliminates spatial learning deficits.

  Deborah Saucier;Eric L. Hargreaves;Francis Boon;C. H. Vanderwolf

  234
  Citations

• Repeated mild lateral fluid percussion brain injury in the rat causes cumulative long-term behavioral impairments, neuroinflammation, and cortical loss in an animal model of repeated concussion.

  Sandy Richard Shultz;Feng Bao;Vanessa Omana;Charlotte Chiu

  221
  Citations

• Detailed behavioral analysis of water maze acquisition under APV or CNQX: contribution of sensorimotor disturbances to drug-induced acquisition deficits.

  Donald Peter Cain;Deborah Saucier;Jeff Hall;Eric L. Hargreaves

  206
  Citations

• Intracerebroventricular injections of the enteric bacterial metabolic product propionic acid impair cognition and sensorimotor ability in the Long-Evans rat: further development of a rodent model of autism.

  Sandy R. Shultz;Derrick F. MacFabe;Samantha Martin;Jordana Jackson

  189
  Citations

• Testing the NMDA, Long-term Potentiation, and Cholinergic Hypotheses of Spatial Learning

  Donald Peter Cain

  170
  Citations

• Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse

  R. Anderson;J.C. Barnes;T.V.P. Bliss;D.P. Cain

  170
  Citations

• The role of the olfactory bulb in limbic mechanisms.

  Unknown

  170
  Citations

• Retardation of amygdala kindling by antagonism of NMD-aspartate and muscarinic cholinergic receptors: evidence for the summation of excitatory mechanisms in kindling.

  Donald P. Cain;Kathryn A. Desborough;Douglas J. McKitrick

  161
  Citations

• Sub-concussive brain injury in the Long-Evans rat induces acute neuroinflammation in the absence of behavioral impairments

  Sandy R. Shultz;Derrick F. MacFabe;Kelly A. Foley;Roy Taylor

  157
  Citations

• Hyperactivity, hyper-reactivity, and sensorimotor deficits induced by low doses of the N-methyl-d-aspartate non-competitive channel blocker MK801

  Eric L. Hargreaves;Donald P. Cain

  149
  Citations

• Olfactory bulbectomy and mucosal damage: effects on copulation, irritability, and interspecific aggression in male rats.

  Donald P. Cain;George Paxinos

  146
  Citations

• A Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat Brain

  Derrick F. MacFabe;Karina Rodríguez-Capote;Jennifer E. Hoffman;Andrew E. Franklin

  143
  Citations

• LTP, NMDA, genes and learning

  Donald Peter Cain

  138
  Citations

• Epileptiform effects of met-enkephalin, β-endorphin and morphine: Kindling of generalized seizures and potentiation of epileptiform effects by handling

  Donald P. Cain;Michael E. Corcoran

  134
  Citations