World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
115
Citations
46972
World Ranking
4561
National Ranking
2477

Overview

Donald O. Castell was affiliated with the Medical University of South Carolina in the United States throughout their career. Their research primarily contributed to the field of Medicine, with a focus on Surgery, Gastroenterology, Speech and Hearing, Hepatology, and Genetics.

The primary topics associated with Donald O. Castell's work included:

  • Gastroesophageal reflux and treatments
  • Esophageal and gastrointestinal pathology
  • Eosinophilic esophagitis
  • Dysphagia assessment and management
  • Esophageal cancer research and treatment
  • Liver disease and transplantation
  • Helicobacter pylori-related gastroenterology studies

The scientist published research papers in several notable venues, with multiple contributions to:

  • Gastroenterology
  • Neurogastroenterology & Motility
  • The American Journal of Gastroenterology
  • Gut
  • World Journal of Hepatology

Recent published papers included:

  • "Normal values and regional differences in oesophageal impedance-pH metrics: a consensus analysis of impedance-pH studies from around the world," 2020, published in Gut
  • "Development of quality indicators for the diagnosis and management of achalasia," 2021, published in Neurogastroenterology & Motility
  • "Spectrum of esophageal motility disorders in patients with liver cirrhosis," 2020, published in World Journal of Hepatology
  • "Dysphagia lusoria: utility of high-resolution impedance manometry to identify true disease," 2021, published in Neurogastroenterology & Motility
  • "Editorial: simultaneous prolonged monitoring of the acid pocket and oesophageal reflux," 2020, published in Alimentary Pharmacology & Therapeutics

Frequent collaborators included Sabine Roman, Edoardo Savarino, C. Prakash Gyawali, Philip O. Katz, and Puja S. Elias, each having coauthored multiple works with the scientist.

Best Publications

  • Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease

    Kenneth R. DeVault;Donald O. Castell

  • Symptomatic gastroesophageal reflux: Incidence and precipitating factors

    Otto T. Nebel;Michael F. Fornes;Donald O. Castell

  • Gastro-oesophageal reflux monitoring: review and consensus report on detection and definitions of acid, non-acid, and gas reflux

    Daniel Sifrim;D Castell;P J Kahrilas

  • Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy. A multicentre study using combined ambulatory impedance-pH monitoring

    Inder Mainie;Radu Tutuian;Steven Shay;Marcelo Vela

  • Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: Effect of omeprazole * **

    Marcelo F. Vela;Luciana Camacho-Lobato;Ramesh Srinivasan;Radu Tutuian

  • Classification of oesophageal motility abnormalities

    S J Spechler;D O Castell

  • Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of "abnormal" contractions.

    Joel E. Richter;Wallace C. Wu;Doree N. Johns;John N. Blackwell

  • Twenty-four hour ambulatory simultaneous impedance and pH monitoring: A multicenter report of normal values from 60 healthy volunteers

    Steven Shay;Radu Tutuian;Daniel Sifrim;Marcelo Vela

  • The symptom index: a clinically important parameter of ambulatory 24-hour esophageal pH monitoring.

    Wiener Gj;Richter Je;Copper Jb;Wu Wc

  • MBS Measurement Tool for Swallow Impairment—MBSImp: Establishing a Standard

    Bonnie Martin-Harris;Martin B. Brodsky;Yvonne Michel;Donald O. Castell

  • Esophageal Testing of Patients With Noncardiac Chest Pain or Dysphagia. Results of Three Years' Experience With 1161 Patients

    Philip O. Katz;Christine B. Dalton;Joel E. Richter;Wallace C. Wu

  • Esomeprazole (40 mg) compared with lansoprazole (30 mg) in the treatment of erosive esophagitis

    Donald O Castell;Peter J Kahrilas;Joel E Richter;Nimish B Vakil

  • Abnormal sensory perception in patients with esophageal chest pain

    Joel E. Richter;Charles F. Barish;Donald O. Castell

  • Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup survey conducted on behalf of the American Gastroenterological Association

    Reza Shaker;Donald O Castell;Philip S Schoenfeld;Stuart J Spechler

  • Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy

    Joel E. Richter;Donald O. Castell

  • Ambulatory 24-hour esophageal pH monitoring. Reproducibility and variability of pH parameters.

    G J Wiener;T M Morgan;J B Copper;W C Wu

  • Ineffective esophageal motility (IEM): the primary finding in patients with nonspecific esophageal motility disorder.

    Louis P. Leite;Brian T. Johnston;Jeffrey Barrett;June A. Castell

  • Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: A controlled study in normal subjects

    Paolo L. Peghini;Philip O. Katz;Donald O. Castell

  • Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group.

    S. Roman;C. P. Gyawali;E. Savarino;R. Yadlapati

  • Combined multichannel intraluminal impedance–pH monitoring to select patients with persistent gastro-oesophageal reflux for laparoscopic Nissen fundoplication

    I. Mainie;R. Tutuian;A. Agrawal;D. Adams

Frequent Co-Authors

Joel E. Richter
Joel E. Richter University of South Florida
Stuart J. Spechler
Stuart J. Spechler Baylor University Medical Center
Peter J. Kahrilas
Peter J. Kahrilas Northwestern University
John E. Pandolfino
John E. Pandolfino Northwestern University
Daniel Sifrim
Daniel Sifrim Queen Mary University of London
Edoardo Savarino
Edoardo Savarino University of Padua
Albert J. Bredenoord
Albert J. Bredenoord University of Amsterdam
Michael F. Vaezi
Michael F. Vaezi Vanderbilt University Medical Center
Laurence A. Bradley
Laurence A. Bradley University of Alabama at Birmingham
Reza Shaker
Reza Shaker Medical College of Wisconsin

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