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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
9275
World Ranking
16247
National Ranking
1140

Overview

Dirk Koczan is affiliated with the University of Rostock in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a notable focus on several subfields including Molecular Biology, Genetics, Oncology, Cancer Research, and Immunology.

The scientist's work covers a range of topics, particularly emphasizing areas such as Reproductive Biology and Fertility, Reproductive Physiology in Livestock, Protein Degradation and Inhibitors, Cancer Research and Treatments, Neuroblastoma Research and Treatments, Cancer-related Molecular Pathways, and Cancer-related molecular mechanisms research.

Frequently publishing in journals like Frontiers in Immunology, Cells, BMC Genomics, Cell Death Discovery, and EBioMedicine, Dirk Koczan has contributed multiple papers to these venues. Their recent papers include:

  • Cyclin-dependent kinase inhibitors exert distinct effects on patient-derived 2D and 3D glioblastoma cell culture models, 2021, Cell Death Discovery
  • ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars-A Combined In Vitro and In Silico Study, 2020, Cells
  • Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis, 2020, EBioMedicine
  • Trophoblast cell differentiation in the bovine placenta: differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis, 2020, BMC Molecular and Cell Biology
  • Implementation of a combined CDK inhibition and arginine-deprivation approach to target arginine-auxotrophic glioblastoma multiforme cells, 2022, Cell Death and Disease

Dirk Koczan's frequent coauthors include Claudia Maletzki, Jens Vanselow, Michael Hecker, Brit Fitzner, and Uwe K. Zettl, reflecting a collaborative research environment.

Best Publications

  • Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis.

    Harald H. Hofstetter;Saleh M. Ibrahim;Dirk Koczan;Niels Kruse

  • Gene Expression Signatures for Tumor Progression, Tumor Subtype, and Tumor Thickness in Laser-Microdissected Melanoma Tissues

    Jochen Jaeger;Dirk Koczan;Hans Juergen Thiesen;Saleh M. Ibrahim

  • Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation

    Dirk Woetzel;Rene Huber;Peter Kupfer;Dirk Pohlers

  • Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli

    Juliane Günther;Dirk Koczan;Wei Yang;Gerd Nürnberg

  • Interleukin-6–dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family–independent survival pathway closely associated with Stat3 activation

    Katja Brocke-Heidrich;Katja Brocke-Heidrich;Katja Brocke-Heidrich;Antje K. Kretzschmar;Antje K. Kretzschmar;Antje K. Kretzschmar;Gabriele Pfeifer;Gabriele Pfeifer;Gabriele Pfeifer;Christian Henze;Christian Henze;Christian Henze

  • Autoantibodies against the exocrine pancreas in autoimmune pancreatitis: gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process.

    J. Matthias Löhr;J. Matthias Löhr;J. Matthias Löhr;Ralf Faissner;Dirk Koczan;Peter Bewerunge

  • Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules.

    Dirk Koczan;Reinhard Guthke;Hans-Jürgen Thiesen;Saleh M Ibrahim

  • Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept

    Dirk Koczan;Susanne Drynda;Michael Hecker;Andreas Drynda

  • Increased osteoblast viability at alkaline pH in vitro provides a new perspective on bone regeneration.

    Anne-Marie Galow;Alexander Rebl;Dirk Koczan;Sebastian M. Bonk

  • A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas

    Fei Ling Lim;Marielle Soulez;Dirk Koczan;Hans-Jürgen Thiesen

  • Molecular signatures and new candidates to target the pathogenesis of rheumatoid arthritis.

    U. Ungethuem;T. Haeupl;H. Witt;H. Witt;D. Koczan

  • Constitutive upregulation of the transforming growth factor-β pathway in rheumatoid arthritis synovial fibroblasts

    Dirk Pohlers;Andreas Beyer;Andreas Beyer;Dirk Koczan;Thomas Wilhelm

  • E2F1 in Melanoma Progression and Metastasis

    Vijay Alla;David Engelmann;Annett Niemetz;Jens Pahnke

  • Microarray analysis of differentially expressed genes in placental tissue of pre-eclampsia: up-regulation of obesity-related genes

    T. Reimer;D. Koczan;B. Gerber;D. Richter

  • MicroRNA Expression Changes during Interferon-Beta Treatment in the Peripheral Blood of Multiple Sclerosis Patients

    Michael Hecker;Madhan Thamilarasan;Dirk Koczan;Ina Schröder

  • FasL:Fas Ratio–A Prognostic Factor in Breast Carcinomas

    Toralf Reimer;Christina Herrnring;Dirk Koczan;Dagmar Richter

  • High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis

    Peter Ruschpler;Peter Lorenz;Wolfram Eichler;Dirk Koczan

  • Gene expression profiling of the nervous system in murine experimental autoimmune encephalomyelitis

    Saleh M. Ibrahim;Eilhard Mix;Tobias Böttcher;Dirk Koczan

  • Mechanisms of hypoxic gene regulation of angiogenesis factor Cyr61 in melanoma cells.

    Manfred Kunz;Steffen Moeller;Dirk Koczan;Peter Lorenz

  • Anoxia-Induced Up-Regulation of Interleukin-8 in Human Malignant Melanoma: A Potential Mechanism for High Tumor Aggressiveness

    Manfred Kunz;Anke Hartmann;Egbert Flory;Atiye Toksoy

Frequent Co-Authors

Michael Hecker
Michael Hecker University of Greifswald
Reinhard Guthke
Reinhard Guthke Leibniz Association
Uwe Haberkorn
Uwe Haberkorn Heidelberg University
Jörn Bullerdiek
Jörn Bullerdiek University of Bremen
Olaf Wolkenhauer
Olaf Wolkenhauer University of Rostock
Thomas Häupl
Thomas Häupl Charité - University Medicine Berlin
Mauro Magnani
Mauro Magnani University of Urbino
Bernd Kreikemeyer
Bernd Kreikemeyer University of Rostock
Roland Eils
Roland Eils Charité - University Medicine Berlin
Benedikt Brors
Benedikt Brors German Cancer Research Center

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