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Didier Dulon

Didier Dulon

D-Index & Metrics

Neuroscience

D-Index
40
Citations
4820
World Ranking
8189
National Ranking
379

Overview

Didier Dulon is affiliated with Inserm in France and specializes in neuroscience, particularly focusing on sensory systems and auditory processes. Their research spans related subfields including molecular biology, neurology, cognitive neuroscience, and physiology, contributing notably to the understanding of hearing and cochlear function.

The scientist's main topics of work encompass hearing, cochlea, tinnitus, and genetics, with additional research interests in vestibular and auditory disorders. They also explore RNA regulation and disease mechanisms, ion channels and receptors, cellular transport and secretion, genetics and neurodevelopmental disorders, and autism spectrum disorder research.

Recent publications reflect these areas of expertise and include:

  • Synaptic Release Potentiation at Aging Auditory Ribbon Synapses, 2021, Frontiers in Aging Neuroscience
  • The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses, 2022, iScience
  • Otoferlin as a multirole Ca2+ signaling protein: from inner ear synapses to cancer pathways, 2023, Frontiers in Cellular Neuroscience
  • Clarin-2 gene supplementation durably preserves hearing in a model of progressive hearing loss, 2024, Molecular Therapy
  • Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels, 2023, International Journal of Molecular Sciences

Dulon has collaborated frequently with a number of researchers, including:

  • Yohan Bouleau
  • Thibault Peineau
  • Steven Condamine
  • Susanna Pietropaolo
  • Baptiste Plion

Their work has been published in several venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cellular Neuroscience
  • Frontiers in Aging Neuroscience
  • iScience
  • Molecular Therapy

Best Publications

  • Increasing Intracellular Free Calcium Induces Circumferential Contractions in Isolated Cochlear Outer Hair Cells

    Didier Dulon;Gary Zajic;Jochen Schacht

  • Acetylcholine-induced potassium current of guinea pig outer hair cells: its dependence on a calcium influx through nicotinic-like receptors

    C Blanchet;C Erostegui;M Sugasawa;D Dulon

  • Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes

    Sedigheh Delmaghani;Sedigheh Delmaghani;Sedigheh Delmaghani;Jean Defourny;Jean Defourny;Jean Defourny;Asadollah Aghaie;Asadollah Aghaie;Asadollah Aghaie;Maryline Beurg

  • Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells.

    Didier Dulon;Didier Dulon;Gary Zajic;Jean Marie Aran;Jochen Schacht

  • Control of Exocytosis by Synaptotagmins and Otoferlin in Auditory Hair Cells

    Maryline Beurg;Nicolas Michalski;Saaid Safieddine;Yohan Bouleau

  • Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.

    Didier Dulon;Saaid Safieddine;Sherri M. Jones;Christine Petit;Christine Petit

  • Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses

    Nicolas Antoine Michalski;Nicolas Antoine Michalski;Nicolas Antoine Michalski;Juan D Goutman;Sarah Marie Auclair;Jacques Boutet de Monvel;Jacques Boutet de Monvel;Jacques Boutet de Monvel

  • Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.

    Alice Emptoz;Vincent Michel;Andrea Lelli;Omar Akil

  • Potassium-depolarization induces motility in isolated outer hair cells by an osmotic mechanism

    Didier Dulon;Jean Marie Aran;Jochen Schacht

  • Localization and developmental expression of BK channels in mammalian cochlear hair cells.

    A Hafidi;M Beurg;D Dulon

  • Contribution of BK Ca2+-Activated K+ Channels to Auditory Neurotransmission in the Guinea Pig Cochlea

    Liam J. Skinner;Véronique Enée;Maryline Beurg;Hak Hyun Jung

  • Calcium- and Otoferlin-Dependent Exocytosis by Immature Outer Hair Cells

    Maryline Beurg;Saaid Safieddine;Isabelle Roux;Yohan Bouleau

  • ATP activates non-selective cation channels and calcium release in inner hair cells of the guinea-pig cochlea.

    M Sugasawa;C Erostegui;C Blanchet;D Dulon

  • Osmotically induced motility of outer hair cells: implications for Menière's disease

    D. Dulon;J. M. Aran;J. Schacht

  • Photo-released intracellular Ca2+ evokes reversible mechanical responses in supporting cells of the guinea-pig organ of Corti.

    D. Dulon;C. Blanchet;E. Laffon

  • Expression of small-conductance calcium-activated potassium channels (SK) in outer hair cells of the rat cochlea.

    Didier Dulon;Lin Luo;Chunyan Zhang;Allen F. Ryan

  • Comparative uptake of gentamicin, netilmicin, and amikacin in the guinea pig cochlea and vestibule.

    D Dulon;J M Aran;G Zajic;J Schacht

  • Extracellular ATP elevates cytosolic Ca2+ in cochlear inner hair cells.

    Didier Dulon;Patrice Mollard;Jean-Marie Aran

  • Cholinergic Responses in Developing Outer Hair Cells of the Rat Cochlea

    Didier Dulon;Marc Lenoir

  • Gentamicin Uptake by Cochlear Hair Cells Precedes Hearing Impairment during Chronic Treatment

    Hakim Hiel;Jean Paul Erre;Catherine Aurousseau;Rabia Bouali

  • Dynamic changes following combined treatment with gentamicin and ethacrynic acid with and without acoustic stimulation. Cellular uptake and functional correlates.

    Tetsuro Hayashida;Hakim Hiel;Didier Dulon;Jean Paul Erre

Frequent Co-Authors

Christine Petit
Christine Petit Université Paris Cité
Paul Avan
Paul Avan University of Clermont Auvergne
Timothy J. Mitchell
Timothy J. Mitchell University of Birmingham
Henrique von Gersdorff
Henrique von Gersdorff Oregon Health & Science University
E. Sylvester Vizi
E. Sylvester Vizi Institute of Experimental Medicine
James C. Saunders
James C. Saunders University of Pennsylvania
Steve D.M. Brown
Steve D.M. Brown Medical Research Council
Ralf Schneggenburger
Ralf Schneggenburger École Polytechnique Fédérale de Lausanne
Alain Sans
Alain Sans University of Montpellier

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