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Neuroscience

D-Index
37
Citations
7653
World Ranking
8709
National Ranking
3695

Overview

David Z.Z. He is affiliated with Creighton University in the United States. Their research primarily focuses on neuroscience and biochemistry, genetics, and molecular biology, with significant contributions to sensory systems, molecular biology, cognitive neuroscience, neurology, and cancer research. The main topics covered in their work include hearing, cochlea, tinnitus, genetics, vestibular and auditory disorders, cancer-related molecular mechanisms research, hearing loss and rehabilitation, ion channels and receptors, synthesis of organic compounds, and calcium signaling and nucleotide metabolism.

The scientist has authored numerous recent papers, including:

  • Molecular and cytological profiling of biological aging of mouse cochlear inner and outer hair cells, 2022, Cell Reports
  • BRAF inhibition protects against hearing loss in mice, 2020, Science Advances
  • Profiling mouse cochlear cell maturation using 10× Genomics single-cell transcriptomics, 2022, Frontiers in Cellular Neuroscience
  • Endolymphatic Potential Measured From Developing and Adult Mouse Inner Ear, 2020, Frontiers in Cellular Neuroscience
  • Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction, 2022, Science Advances

Frequent coauthors contributing to the research include Huizhan Liu, Yi Li, Kimberlee P. Giffen, Marisa Zallocchi, and Lei Chen.

Publications have often appeared in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Cellular Neuroscience, Science Advances, JCI Insight, and Frontiers in Neurology.

David Z.Z. He has contributed to book publications as well, including "Hair Cells: From Molecules to Function, Volume II," published by Frontiers Media in 2022.

Best Publications

  • Prestin is the motor protein of cochlear outer hair cells.

    Jing Zheng;Weixing Shen;David Z. Z. He;Kevin B. Long

  • Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier.

    M. Charles Liberman;Jiangang Gao;David Z. Z. He;Xudong Wu;Xudong Wu

  • Intracellular anions as the voltage sensor of prestin, the outer hair cell motor protein

    Dominik Oliver;David Z. Z. He;Nikolaj Klöcker;Jost Ludwig

  • Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification

    Peter Dallos;Xudong Wu;Mary Ann Cheatham;Jiangang Gao

  • Acetylcholine, outer hair cell electromotility, and the cochlear amplifier

    Peter Dallos;David Z. Z. He;Xi Lin;István Sziklai

  • Characterization of transcriptomes of cochlear inner and outer hair cells.

    Huizhan Liu;Jason L. Pecka;Qian Zhang;Garrett A. Soukup

  • Somatic stiffness of cochlear outer hair cells is voltage-dependent

    David Z. Z. He;Peter Dallos

  • First appearance and development of electromotility in neonatal gerbil outer hair cells

    David Z.Z. He;Burt N. Evans;Peter Dallos

  • Mechanoelectrical transduction of adult outer hair cells studied in a gerbil hemicochlea

    David Z. Z. He;Shuping Jia;Peter Dallos

  • Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing.

    Paul T. Ranum;Paul T. Ranum;Alexander T. Goodwin;Hidekane Yoshimura;Hidekane Yoshimura;Diana L. Kolbe

  • Regeneration of Stereocilia of Hair Cells by Forced Atoh1 Expression in the Adult Mammalian Cochlea

    Shi Ming Yang;Wei Chen;Wei Wei Guo;Shuping Jia

  • Motility-associated hair-bundle motion in mammalian outer hair cells.

    Shuping Jia;David Z Z He

  • Molecular Epidemiology and Functional Assessment of Novel Allelic Variants of SLC26A4 in Non-Syndromic Hearing Loss Patients with Enlarged Vestibular Aqueduct in China

    Yongyi Yuan;Weiwei Guo;Jie Tang;Guozheng Zhang

  • Prestin and the Dynamic Stiffness of Cochlear Outer Hair Cells

    David Z Z He;Shuping Jia;Peter Dallos

  • Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells

    Huizhan Liu;Lei Chen;Kimberlee P. Giffen;Sean T. Stringham

  • Mechanoelectric Transduction of Adult Inner Hair Cells

    Shuping Jia;Peter Dallos;David Z Z He

  • Fate of Mammalian Cochlear Hair Cells and Stereocilia after Loss of the Stereocilia

    Shuping Jia;Shiming Yang;Weiwei Guo;David Z.Z. He

  • Transcriptomes of cochlear inner and outer hair cells from adult mice

    Yi Li;Yi Li;Huizhan Liu;Kimberlee P. Giffen;Lei Chen

  • Organ of Corti and Stria Vascularis: Is there an Interdependence for Survival?

    Huizhan Liu;Yi Li;Yi Li;Lei Chen;Qian Zhang

  • Properties of voltage-dependent somatic stiffness of cochlear outer hair cells.

    David Z.Z. He;Peter Dallos

  • Effect of acetylcholine and GABA on the transfer function of electromotility in isolated outer hair cells

    István Sziklai;David Z.Z. He;Peter Dallos

  • From Zebrafish to Mammal: Functional Evolution of Prestin, the Motor Protein of Cochlear Outer Hair Cells

    Xiaodong Tan;Jason L. Pecka;Jie Tang;Oseremen E. Okoruwa

  • Apoptosis in inner ear sensory hair cells.

    Seth Morrill;David Z.Z. He

Frequent Co-Authors

Peter Dallos
Peter Dallos Northwestern University
Jian Zuo
Jian Zuo Creighton University
Bernd Fritzsch
Bernd Fritzsch University of Nebraska Medical Center
Yu-Qiang Ding
Yu-Qiang Ding Fudan University
M. Charles Liberman
M. Charles Liberman Massachusetts Eye and Ear Infirmary
John Wood
John Wood University College London
Marlies Knipper
Marlies Knipper University of Tübingen
Richard Salvi
Richard Salvi University at Buffalo, State University of New York
David W. Burt
David W. Burt University of Queensland
Ning Pan
Ning Pan University of California, Davis

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