World's Best Scientists 2026 revealed!
David M. Irwin

David M. Irwin

D-Index & Metrics

Genetics

D-Index
59
Citations
13689
World Ranking
3231
National Ranking
121

Overview

David M. Irwin is affiliated with the University of Toronto in Canada. Their research spans across multiple fields related to biochemistry, genetics, molecular biology, and medicine, with a focus on understanding molecular mechanisms in infectious diseases and genetics.

The main fields of study associated with their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, the subfields of study are diverse and include:

  • Molecular Biology
  • Infectious Diseases
  • Genetics
  • Animal Science and Zoology
  • Epidemiology

The topics frequently addressed in their research reveal a focus oriented towards viral infections, genetics, and host pathogen interactions. Key topics include:

  • SARS-CoV-2 and COVID-19 Research
  • Animal Virus Infections Studies
  • Viral gastroenteritis research and epidemiology
  • RNA and protein synthesis mechanisms
  • Gut microbiota and health
  • Genetic diversity and population structure
  • Genetic and phenotypic traits in livestock

David M. Irwin has published extensively in notable scientific journals, with frequent publication venues being:

  • Frontiers in Microbiology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Frontiers in Genetics
  • Research Square (Research Square)

Notable recent papers include:

  • Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration, 2020, Nature Communications
  • Decoding the RNA viromes in rodent lungs provides new insight into the origin and evolutionary patterns of rodent-borne pathogens in Mainland Southeast Asia, 2021, Microbiome
  • Base Composition and Host Adaptation of the SARS-CoV-2: Insight From the Codon Usage Perspective, 2021, Frontiers in Microbiology
  • Emergence of SARS-like coronavirus poses new challenge in China, 2020, Journal of Infection
  • Virus diversity, wildlife-domestic animal circulation and potential zoonotic viruses of small mammals, pangolins and zoo animals, 2023, Nature Communications

The scientist collaborates frequently with a group of coauthors, some of whom have contributed extensively to their body of work. These include:

  • Yongyi Shen
  • Shuyi Zhang
  • Xuejuan Shen
  • Junpeng Zhang
  • Xianghui Liang

Best Publications

  • Evolution of the cytochrome b gene of mammals.

    David M. Irwin;Thomas D. Kocher;Allan C. Wilson

  • DNA damage promotes jumping between templates during enzymatic amplification

    Svante Pääbo;D.M. Irwin;A.C. Wilson

  • The genomics of selection in dogs and the parallel evolution between dogs and humans

    Guo-dong Wang;Weiwei Zhai;He-chuan Yang;He-chuan Yang;Ruo-xi Fan

  • Out of southern East Asia: the natural history of domestic dogs across the world.

    Guo-Dong Wang;Weiwei Zhai;He-Chuan Yang;He-Chuan Yang;He-Chuan Yang;Lu Wang

  • Adaptive evolution of energy metabolism genes and the origin of flight in bats

    Yong-Yi Shen;Lu Liang;Lu Liang;Zhou-Hai Zhu;Wei-Ping Zhou;Wei-Ping Zhou

  • Draft genome sequence of the Tibetan antelope

    Ri Li Ge;Qingle Cai;Yong Yi Shen;Yong Yi Shen;A. San

  • Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes

    Yan Bo Sun;Zi Jun Xiong;Xue Yan Xiang;Shi Ping Liu

  • Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens

    Ming-Shan Wang;Yan Li;Min-Sheng Peng;Li Zhong

  • De novo origin of human protein-coding genes.

    Dong-Dong Wu;David M. Irwin;David M. Irwin;Ya-Ping Zhang;Ya-Ping Zhang

  • Cytochromeb gene of marine mammals: Phylogeny and evolution

    David M. Irwin;Úlfur Árnason

  • Human genes encoding prothrombin and ceruloplasmin map to 11p11-q12 and 3q21-24, respectively.

    N. J. Royle;D. M. Irwin;M. L. Koschinsky;R. T. A. MacGillivray

  • Population variation revealed high altitude adaptation of Tibetan Mastiffs

    Yan Li;Dong-Dong Wu;Dong-Dong Wu;Adam R. Boyko;Guo-Dong Wang;Guo-Dong Wang

  • Glucagon-like peptide 1 increases insulin sensitivity in depancreatized dogs.

    H Sandhu;S R Wiesenthal;P E MacDonald;R H McCall

  • Trout and chicken proglucagon: alternative splicing generates mRNA transcripts encoding glucagon-like peptide 2.

    D M Irwin;J Wong

  • Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair

    Dong-Dong Wu;Dong-Dong Wu;David M Irwin;Ya-Ping Zhang;Ya-Ping Zhang

  • Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation

    Li Yu;Guo Dong Wang;Jue Ruan;Yong Bin Chen

  • Molecular evolution of vertebrate goose-type lysozyme genes.

    David M. Irwin;Zhiyuan M. Gong

  • Domestication genomics: evidence from animals.

    Guo-Dong Wang;Hai-Bing Xie;Min-Sheng Peng;David Irwin

  • Evaluating the Roles of Energetic Functional Constraints on Teleost Mitochondrial-Encoded Protein Evolution

    Yan-Bo Sun;Yan-Bo Sun;Yong-Yi Shen;Yong-Yi Shen;David M. Irwin;Ya-Ping Zhang;Ya-Ping Zhang

  • Isogenic strain construction and gene mapping in Candida albicans.

    David M. Irwin;W A Fonzi;Daniel Wai Hung Ho;sebnem ozemri sag

Frequent Co-Authors

Ya-Ping Zhang
Ya-Ping Zhang Kunming Institute of Zoology
Shuyi Zhang
Shuyi Zhang Shenyang Agricultural University
Allan C. Wilson
Allan C. Wilson University of California, Berkeley
Robert W. Murphy
Robert W. Murphy University of Toronto
Yong-Gang Yao
Yong-Gang Yao Chinese Academy of Sciences
Chung-I Wu
Chung-I Wu Sun Yat-sen University
Ali Esmailizadeh
Ali Esmailizadeh Shahid Bahonar University of Kerman
Wen Wang
Wen Wang Northwestern Polytechnical University
John H. Youson
John H. Youson University of Toronto
Michael B. Wheeler
Michael B. Wheeler University of Toronto

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA can open doors to many healthcare and science careers. If you are considering alternative or complementary degree options, plenty of flexible online programs can help you quickly advance in related fields.

For those with a background in nursing, rn to bsn programs with no clinicals provide a convenient way to upskill without traditional clinical requirements. Busy professionals who wish to advance further may be interested in the fastest dnp program, which can lead to higher leadership roles in healthcare.

If your career goals involve entering the medical field quickly, consider medical assistant programs accelerated that offer training and certification in as little as six weeks. For those seeking maximum flexibility in doctoral-level nursing, dnp programs online provide accessible options for advancing your education and career without leaving your current job.

Exploring these related online degrees can help you find the best pathway to pursue your interests in genetics, healthcare, and biomedical research.

Best Scientists Citing David M. Irwin

Trending Scientists