World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
40
Citations
4933
World Ranking
8178
National Ranking
3502

Overview

Brian A. McCool is affiliated with Wake Forest University in the United States, with a research focus largely centered on neuroscience. Their work has contributed to the understanding of neural mechanisms, particularly in the areas of cellular and molecular neuroscience, cognitive neuroscience, molecular biology, behavioral neuroscience, and social psychology.

The scientist's research spans a range of topics, including:

  • Neuroscience and Neuropharmacology Research
  • Memory and Neural Mechanisms
  • Neurotransmitter Receptor Influence on Behavior
  • Nicotinic Acetylcholine Receptors Study
  • Stress Responses and Cortisol
  • Neuroendocrine Regulation and Behavior
  • Circadian Rhythm and Melatonin

Brian A. McCool has authored several papers published in a variety of scientific journals. These include:

  • "Withdrawal from chronic ethanol exposure increases postsynaptic glutamate function of insular cortex projections to the rat basolateral amygdala" (2020) in Neuropharmacology
  • "Structural, functional, and behavioral significance of sex and gonadal hormones in the basolateral amygdala: A review of preclinical literature" (2021) in Alcohol
  • "Chronic Alcohol Dysregulates Glutamatergic Function in the Basolateral Amygdala in a Projection-and Sex-Specific Manner" (2022) in Frontiers in Cellular Neuroscience
  • "Chronic Ethanol Exposure Potentiates Cholinergic Neurotransmission in the Basolateral Amygdala" (2020) in Neuroscience
  • "Ethanol modulation of cortico-basolateral amygdala circuits: Neurophysiology and behavior" (2021) in Neuropharmacology

The frequent coauthors of Brian A. McCool include Michaela E. Price, Brian C. Parrish, Sarah E. Sizer, Kimberly F. Raab-Graham, and Haiguo Sun. This reflects collaborative work across multiple related studies.

In terms of publication venues, their work has appeared most often in:

  • Neuropharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alcohol
  • Frontiers in Cellular Neuroscience
  • Neuroscience

Brian A. McCool's primary field of study is Neuroscience, with 23 publications contributing to the larger body of knowledge in this domain. Within this, 14 publications focus on Cellular and Molecular Neuroscience, seven on Cognitive Neuroscience, and several others spread across Molecular Biology, Behavioral Neuroscience, and Social Psychology.

Best Publications

  • Substitution of a mutant alpha2a-adrenergic receptor via "hit and run" gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo.

    Parul P. Lakhlani;Leigh B. MacMillan;Tian Zhi Guo;Brian A. McCool

  • Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3

    D. M. Lovinger;B. A. McCool

  • Nonhuman primate parthenogenetic stem cells.

    Kent E. Vrana;Jason D. Hipp;Ashley M. Goss;Brian A. McCool

  • Chronic ethanol and withdrawal differentially modulate pre- and postsynaptic function at glutamatergic synapses in rat basolateral amygdala.

    Anna K. Läck;Marvin R. Diaz;Ann Chappell;Dustin W. DuBois

  • Early Social Isolation in Male Long‐Evans Rats Alters Both Appetitive and Consummatory Behaviors Expressed During Operant Ethanol Self‐Administration

    Brian A. McCool;Ann M. Chappell

  • Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: Subtype-specific coupling to ion channels

    Stephen R Ikeda;David M Lovinger;Brian A McCool;Deborah L Lewis

  • Supersensitive Kappa Opioid Receptors Promotes Ethanol Withdrawal-Related Behaviors and Reduce Dopamine Signaling in the Nucleus Accumbens

    Jamie H. Rose;Anushree N. Karkhanis;Rong Chen;Dominic Gioia

  • Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats.

    Ann M. Chappell;Eugenia Carter;Brian A. McCool;Jeff L. Weiner

  • Chronic Ethanol Ingestion Facilitates N -Methyl-d-aspartate Receptor Function and Expression in Rat Lateral/Basolateral Amygdala Neurons

    Donald W. Floyd;Ki-Yoon Jung;Brian A. McCool

  • Neurobiological mechanisms contributing to alcohol-stress-anxiety interactions.

    Yuval Silberman;Michal Bajo;Ann M. Chappell;Daniel T. Christian

  • Ethanol modulation of synaptic plasticity

    Brian A. McCool

  • Cloning of human transketolase cDNAs and comparison of the nucleotide sequence of the coding region in Wernicke-Korsakoff and non-Wernicke-Korsakoff individuals.

    B.A. McCool;S.G. Plonk;P.R. Martin;C.K. Singleton

  • Dopamine D3-Like Receptors Modulate Anxiety-Like Behavior and Regulate GABAergic Transmission in the Rat Lateral/Basolateral Amygdala

    Marvin R Diaz;Ann M Chappell;Daniel T Christian;Nancy J Anderson

  • Locomotor Sensitization to Ethanol Impairs NMDA Receptor-Dependent Synaptic Plasticity in the Nucleus Accumbens and Increases Ethanol Self-Administration

    Karina Possa Abrahao;Olusegun J Ariwodola;Tracy R Butler;Andrew R Rau

  • Effects of chronic alcohol exposure on dopamine uptake in rat nucleus accumbens and caudate putamen

    Evgeny A. Budygin;Erik B. Oleson;Tiffany A. Mathews;Anna K. Läck

  • Ifenprodil inhibition of the 5-Hydroxytryptamine3 receptor

    B.A. Mccool;D.M. Lovinger

  • SOCIAL ISOLATION REARING INCREASES NUCLEUS ACCUMBENS DOPAMINE AND NOREPINEPHRINE RESPONSES TO ACUTE ETHANOL IN ADULTHOOD

    Anushree N. Karkhanis;Jason L. Locke;Brian A. McCool;Jeffrey L. Weiner

  • Chronic ethanol ingestion modulates proanxiety factors expressed in rat central amygdala

    Anna K. Läck;Donald W. Floyd;Brian A. McCool

  • Chronic Intermittent Ethanol and Withdrawal Differentially Modulate Basolateral Amygdala AMPA-type Glutamate Receptor Function and Trafficking

    Daniel T. Christian;Nancy J. Alexander;Marvin R. Diaz;Stacey Robinson

  • Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats.

    Melissa Morales;Molly M. McGinnis;Brian A. McCool

  • Effects of Chronic Ethanol Consumption on Rat GABAA and Strychnine-sensitive Glycine Receptors Expressed by Lateral/ Basolateral Amygdala Neurons

    Brian A. McCool;Gerald D. Frye;Marisa D. Pulido;Shaleen K. Botting

  • Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells.

    Brian A. McCool;Jean-Phillipe Pin;Michael M. Harpold;Paul F. Brust

  • Characterization of strychnine-sensitive glycine receptors in acutely isolated adult rat basolateral amygdala neurons

    Brian A McCool;Shaleen K Botting

Frequent Co-Authors

Jeff L. Weiner
Jeff L. Weiner Wake Forest University
David M. Lovinger
David M. Lovinger National Institutes of Health
David Friedman
David Friedman Columbia University
Sara R. Jones
Sara R. Jones Wake Forest University
Derek A. Hamilton
Derek A. Hamilton University of New Mexico
George R. Siggins
George R. Siggins Scripps Research Institute
Thomas L. Kash
Thomas L. Kash University of North Carolina at Chapel Hill
Danny G. Winder
Danny G. Winder Vanderbilt University
Robert O. Messing
Robert O. Messing The University of Texas at Austin
Stephen R. Ikeda
Stephen R. Ikeda National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Neuroscience can open doors to a wide variety of online degree options and career pathways. For those looking to make an impact in social services, pursuing the cheapest online master's in social work is a cost-effective way to gain specialized training and qualify for roles in mental health and counseling.

If you're interested in applied behavior analysis, consider enrolling in the cheapest bcba online program to become a Board Certified Behavior Analyst—an in-demand credential for working with individuals with developmental challenges.

Want to accelerate your career? There are options to earn a fast track social work degree online, allowing motivated learners to quickly advance into the workforce while still gaining essential skills.

A classic pathway is the online psychology degree, which provides foundational knowledge for many neuroscience-related fields, including research, clinical services, and education.

By exploring these related degrees, students can align their interests in neuroscience with flexible, affordable, and accredited online programs—empowering a diverse range of career opportunities.

Best Scientists Citing Brian A. McCool

Trending Scientists

Recently Published Articles