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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
46172
World Ranking
9943
National Ranking
4350

Overview

Andrew J. Gentles is a researcher affiliated with Stanford University in the United States. Their work spans multiple fields of study, primarily focusing on medicine, biochemistry, genetics and molecular biology, as well as immunology and microbiology. Within these broader areas, their research delves into several subfields, including immunology, molecular biology, oncology, cancer research, and hematology.

Their recent scholarly contributions include papers published in high-impact journals. Notable publications are:

  • Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling, 2021, Science
  • Lymph node colonization induces tumor-immune tolerance to promote distant metastasis, 2022, Cell
  • CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities, 2020, Nature
  • Atlas of clinically distinct cell states and ecosystems across human solid tumors, 2021, Cell
  • The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma, 2021, Cancer Cell

Andrew J. Gentles' research topics cover diverse areas related to cancer and immunology. Key topics of their work include:

  • Single-cell and spatial transcriptomics
  • CAR-T cell therapy research
  • Cancer immunotherapy and biomarkers
  • Cancer genomics and diagnostics
  • Immunotherapy and immune responses
  • Immune cell function and interaction
  • T-cell and B-cell immunology

They have collaborated frequently with several coauthors, indicating strong research partnerships in their field. Regular collaborators include Aaron M. Newman, Bogdan Luca, John B. Sunwoo, Sylvia K. Plevritis, and Ravindra Majeti.

Andrew J. Gentles has published extensively across several scientific venues, with multiple contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Blood
  • Cell Reports
  • Nature Communications

Best Publications

  • Robust enumeration of cell subsets from tissue expression profiles

    Aaron M. Newman;Chih Long Liu;Michael R. Green;Andrew J. Gentles

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Determining cell type abundance and expression from bulk tissues with digital cytometry.

    Aaron M. Newman;Chloé B. Steen;Chloé B. Steen;Chih Long Liu;Andrew J. Gentles

  • The prognostic landscape of genes and infiltrating immune cells across human cancers

    Andrew J Gentles;Aaron M Newman;Chih Long Liu;Scott V Bratman;Scott V Bratman

  • Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

    Tathiane M Malta;Artem Sokolov;Andrew J Gentles;Tomasz Burzykowski

  • The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

    Stephen B. Willingham;Jens Peter Volkmer;Andrew J. Gentles;Debashis Sahoo

  • Annotation, submission and screening of repetitive elements in Repbase: RepbaseSubmitter and Censor

    Oleksiy Kohany;Andrew J Gentles;Lukasz Hankus;Jerzy Jurka

  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

    Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Matthew J. Wakefield;Bronwen Aken;Chris T. Amemiya

  • Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

    Mark P. Chao;Siddhartha Jaiswal;Siddhartha Jaiswal;Rachel Weissman-Tsukamoto;Ash A. Alizadeh

  • Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.

    Evan W. Weber;Kevin R. Parker;Elena Sotillo;Rachel C. Lynn

  • Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.

    Andrew J. Gentles;Sylvia K. Plevritis;Ravindra Majeti;Ash A. Alizadeh

  • A Simple Method for Estimating Interactions Between a Treatment and a Large Number of Covariates

    Lu Tian;Ash A. Alizadeh;Andrew J. Gentles;Robert Tibshirani

  • Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation

    Michael R. Green;Shingo Kihira;Chih Long Liu;Ramesh V. Nair

  • Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma.

    Michael R. Green;Andrew J. Gentles;Ramesh V. Nair;Jonathan M. Irish;Jonathan M. Irish

  • Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker

    Max Jan;Mark P. Chao;Adriel C. Cha;Ash A. Alizadeh

  • Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance

    Youngtae Jeong;Ngoc T. Hoang;Ngoc T. Hoang;Alexander Lovejoy;Henning Stehr

  • Amino acid runs in eukaryotic proteomes and disease associations

    Samuel Karlin;Luciano Brocchieri;Aviv Bergman;Jan Mrázek

  • CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.

    Kyuho Han;Sarah E. Pierce;Amy Li;Kaitlyn Spees

  • A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients

    Andrew J. Gentles;Ash A. Alizadeh;Su In Lee;June Helen Myklebust

  • Abstract PR09: The prognostic landscape of genes and infiltrating immune cells across human cancers

    Andrew J. Gentles;Aaron M. Newman;Chih Long Liu;Scott V. Bratman

Frequent Co-Authors

Ash A. Alizadeh
Ash A. Alizadeh Stanford University
Maximilian Diehn
Maximilian Diehn Stanford University
Chih Long Liu
Chih Long Liu Stanford University
Yasodha Natkunam
Yasodha Natkunam Stanford University
Ronald Levy
Ronald Levy Stanford University
Jerzy Jurka
Jerzy Jurka Genetic Information Research Institute
Robert B. West
Robert B. West Stanford University
Ranjana H. Advani
Ranjana H. Advani Stanford University
Samuel Karlin
Samuel Karlin Stanford University
Houtan Noushmehr
Houtan Noushmehr Henry Ford Health System

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