2011 - Herman Skolnik Award, American Chemical Society (ACS)
The scientist’s investigation covers issues in Biochemistry, Oligosaccharide, Glycoprotein, Glycolipid and Mass spectrometry. Alexander M. Lawson performs integrative study on Biochemistry and Glycopeptide in his works. Alexander M. Lawson undertakes multidisciplinary investigations into Oligosaccharide and Saccharomyces cerevisiae in his work.
Alexander M. Lawson has researched Glycoprotein in several fields, including Lectin, Mannose, Natural killer cell and Proteome. His Glycolipid study integrates concerns from other disciplines, such as Chondroitin, Chinese hamster ovary cell, Glycome, E-selectin and Protein–protein interaction. His Mass spectrometry research is included under the broader classification of Chromatography.
His primary areas of study are Biochemistry, Oligosaccharide, Chromatography, Glycoprotein and Mass spectrometry. Biochemistry is closely attributed to Molecular biology in his research. The various areas that Alexander M. Lawson examines in his Oligosaccharide study include Glycolipid, Proton NMR, Stereochemistry and Electrospray.
His work on High-performance liquid chromatography, Fast atom bombardment and Thin-layer chromatography as part of general Chromatography study is frequently linked to Glycopeptide, bridging the gap between disciplines. He combines subjects such as Mucin and Carbohydrate conformation with his study of Glycoprotein. His biological study spans a wide range of topics, including Glycosidic bond, Gas chromatography and Ion.
Biochemistry, Oligosaccharide, Mass spectrometry, Stereochemistry and Receptor are his primary areas of study. His studies link Molecular biology with Biochemistry. His Oligosaccharide research is multidisciplinary, incorporating elements of Chondroitin sulfate, Glycosaminoglycan, Chromatography, Glycolipid and Electrospray.
His Stereochemistry research incorporates themes from Branching, Organic chemistry and Ms analysis. His work in Receptor addresses issues such as Microbiology, which are connected to fields such as Cell adhesion, Hyaluronidase and Immunology. In general Glycoprotein, his work in Glycan is often linked to Borohydride linking many areas of study.
His main research concerns Oligosaccharide, Biochemistry, Electrospray, Mass spectrometry and Chondroitin sulfate. His work often combines Oligosaccharide and Saccharomyces cerevisiae studies. His study in Glycoprotein and Enzyme is carried out as part of his studies in Biochemistry.
His Glycoprotein research integrates issues from Glycolipid, Monoclonal antibody, Chondroitin and Protein–protein interaction. His Electrospray research includes elements of Glycosidic bond, Alginic acid and Mass spectrum. His studies deal with areas such as Glucuronic acid, Proteome, Disaccharide and N-Acetylgalactosamine as well as Chondroitin sulfate.
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Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions
Shigeyuki Fukui;Ten Feizi;Christine Galustian;Alexander M. Lawson.
Nature Biotechnology (2002)
Adhesion of Plasmodium falciparum-infected erythrocytes to hyaluronic acid in placental malaria.
James G. Beeson;Stephen J. Rogerson;Stephen J. Rogerson;Brian M. Cooke;John C. Reeder.
Nature Medicine (2000)
Ligands for the β-glucan receptor, dectin-1, assigned using "designer" microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides
Angelina S. Palma;Ten Feizi;Yibing Zhang;Mark S. Stoll.
Journal of Biological Chemistry (2006)
Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein.
Chun Ting Yuen;Alexander M. Lawson;Wengang Chai;Margot Larkin.
Biochemistry (1992)
Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity.
Karel Bezouška;Chun-Ting Yuen;Jacqui O’Brien;Robert A. Childs.
Nature (1994)
Negative-ion electrospray mass spectrometry of neutral underivatized oligosaccharides.
Wengang Chai;Viadimir Piskarev;Alexander M. Lawson.
Analytical Chemistry (2001)
Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids.
P T Clayton;J V Leonard;A M Lawson;K D Setchell.
Journal of Clinical Investigation (1987)
High prevalence of 2‐mono‐ and 2,6‐di‐substituted Manol‐terminating sequences among O‐glycans released from brain glycopeptides by reductive alkaline hydrolysis
Wengang Chai;Chun-Ting Yuen;Heide Kogelberg;Robert A. Carruthers.
FEBS Journal (1999)
Localization of O-Glycosylation Sites on Glycopeptide Fragments from Lactation-associated MUC1 ALL PUTATIVE SITES WITHIN THE TANDEM REPEAT ARE GLYCOSYLATION TARGETS IN VIVO
Stefan Müller;Steffen Goletz;Nicolle Packer;Andrew Gooley.
Journal of Biological Chemistry (1997)
Brain Contains HNK-1 Immunoreactive O-Glycans of the Sulfoglucuronyl Lactosamine Series that Terminate in 2-Linked or 2,6-Linked Hexose (Mannose)
Chun-Ting Yuen;Wengang Chai;R. Wendy Loveless;Alexander M. Lawson.
Journal of Biological Chemistry (1997)
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