World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
100
Citations
49052
World Ranking
1490
National Ranking
91

Research.com Recognitions

  • 2009 - Fellow of the Mineralogical Society of America
  • 1991 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1984 - Member of the National Academy of Sciences
  • 1982 - Nobel Prize for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes

Overview

Aaron Klug was affiliated with the MRC Laboratory of Molecular Biology in the United Kingdom. Their research focused on fields including Neuroscience and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields such as Cognitive Neuroscience, Molecular Biology, Cellular and Molecular Neuroscience, Sensory Systems, and Developmental Biology.

The scientist's work extensively covered topics related to Neural dynamics and brain function, Hearing, Cochlea, Tinnitus, Genetics, Animal Vocal Communication and Behavior, Hearing Loss and Rehabilitation, Genetics and Neurodevelopmental Disorders, Neuroscience and Neural Engineering, and Advanced Memory and Neural Computing.

The research output included numerous publications in venues such as bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Neuroscience, The Journal of the Acoustical Society of America, Journal of Visualized Experiments, and The FASEB Journal.

  • Mechanisms underlying auditory processing deficits in Fragile X syndrome, 2020, The FASEB Journal
  • Characterization of Auditory and Binaural Spatial Hearing in a Fragile X Syndrome Mouse Model, 2020, eNeuro
  • Myelination Deficits in the Auditory Brainstem of a Mouse Model of Fragile X Syndrome, 2021, Frontiers in Neuroscience
  • Robotic stereotaxic system based on 3D skull reconstruction to improve surgical accuracy and speed, 2020, Journal of Neuroscience Methods
  • Auditory brainstem development of naked mole-rats ( Heterocephalus glaber ), 2022, Proceedings of the Royal Society B Biological Sciences

Frequent collaborators in their research included Shani Poleg, Daniel J. Tollin, Tim C. Lei, Elizabeth A. McCullagh, and Ben-Zheng Li.

Aaron Klug received several distinctions, including the Nobel Prize in 1982 for the development of crystallographic electron microscopy and structural elucidation of biologically important nucleic acid-protein complexes. Additional awards included election as a Member of the National Academy of Sciences in 1984, Fellowship of the American Association for the Advancement of Science (AAAS) in 1991, and Fellowship of the Mineralogical Society of America in 2009.

Best Publications

  • Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.

    J. Miller;A.D. McLachlan;A. Klug

  • Reconstruction of Three Dimensional Structures from Electron Micrographs

    D J De Rosier;A Klug

  • Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

    M Goedert;C M Wischik;R A Crowther;J E Walker

  • The structure of an oligo(dA)·oligo(dT) tract and its biological implications

    Hillary C. M. Nelson;John T. Finch;Bonaventura F. Luisi;Aaron Klug

  • The Reconstruction of a Three-Dimensional Structure from Projections and its Application to Electron Microscopy

    Richard Anthony Crowther;D. J. DeRosier;Aaron Klug

  • Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

    Wesley I. Sundquist;Aaron Klug

  • Structure of yeast phenylalanine tRNA at 3 A resolution.

    J. D. Robertus;Jane E. Ladner;J. T. Finch;Daniela Rhodes

  • Structure of the nucleosome core particle at 7 Å resolution

    T. J. Richmond;J. T. Finch;B. Rushton;D. Rhodes

  • Zinc fingers: a novel protein fold for nucleic acid recognition.

    Aaron Klug;Daniela Rhodes

  • The crystal structure of an all-RNA hammerhead ribozyme: a proposed mechanism for RNA catalytic cleavage.

    William G. Scott;John T. Finch;Aaron Klug

  • Structure of nucleosome core particles of chromatin

    J. T. Finch;L. C. Lutter;D. Rhodes;R. S. Brown

  • ‘Zinc fingers’: a novel protein motif for nucleic acid recognition

    Aaron Klug;Daniela Rhodes

  • Protein motifs 5. Zinc fingers.

    A. Klug;J. W. R. Schwabe

  • The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation

    Aaron Klug

  • Structural characterization of the core of the paired helical filament of Alzheimer disease

    C M Wischik;M Novak;P C Edwards;A Klug

  • Arrangement of Subunits in Flagellar Microtubules

    Linda A. Amos;A. Klug

  • Correlation between segmental mobility and the location of antigenic determinants in proteins

    E. Westhof;D. Altschuh;D. Moras;A. C. Bloomer

  • The tobacco mosaic virus particle: structure and assembly

    A. Klug

  • Diffraction by helical structures

    A. Klug;F. H. C. Crick;H. W. Wyckoff

  • Capturing the Structure of a Catalytic RNA Intermediate: The Hammerhead Ribozyme

    William G. Scott;James B. Murray;John R. P. Arnold;Barry L. Stoddard

Frequent Co-Authors

Daniela Rhodes
Daniela Rhodes Nanyang Technological University
Michel Goedert
Michel Goedert MRC Laboratory of Molecular Biology
Linda A. Amos
Linda A. Amos MRC Laboratory of Molecular Biology
David J. DeRosier
David J. DeRosier Brandeis University
Maria Grazia Spillantini
Maria Grazia Spillantini University of Cambridge
Isidro Sánchez-García
Isidro Sánchez-García University of Salamanca
Ross Jakes
Ross Jakes MRC Laboratory of Molecular Biology
Michal Minczuk
Michal Minczuk University of Cambridge
Andrew Travers
Andrew Travers MRC Laboratory of Molecular Biology

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Best Scientists Citing Aaron Klug