Genes and Development

Top Research Topics at Genes & Development?

The main research concerns discussed in Genes & Development are Cell biology, Genetics, Molecular biology, Gene and Transcription factor. Cell biology research is the primary subject tackled in the journal with a focus on Signal transduction. In the Genetics research discussed, Mutant, RNA splicing, DNA, Mutation and Saccharomyces cerevisiae are all tackled.

RNA splicing research presented in it encompasses a variety of subjects, including Alternative splicing, Exon and Intron. The journal explores topics in Molecular biology which can be helpful for research in disciplines like RNA, Enhancer, Transcription (biology) and Promoter, RNA polymerase II. In particular, the Gene works presented emphasize discussions on Gene expression.

More specifically, the research on Transcription factor in the journal is related to DNA-binding protein. The research on Cellular differentiation discussed in it draws on the closely related field of Stem cell. Genes & Development features Chromatin research that overlaps with concepts in Histone.

• Cell biology (44.83%)
• Genetics (30.15%)
• Molecular biology (28.31%)

What are the most cited papers published in the journal?

• DNA methylation patterns and epigenetic memory (5576 citations)
• CDK inhibitors: positive and negative regulators of G1-phase progression (5323 citations)
• Cellular survival: a play in three Akts (3868 citations)

Research areas of the most cited articles at Genes & Development:

The published papers are organized to reinforce research efforts on Cell biology, Molecular biology, Genetics, Transcription factor and Gene. The most cited articles tackle studies in Cellular differentiation and the interrelated subject of Embryonic stem cell to gain insights into Cell biology. The journal papers with studies in Molecular biology featured incorporate elements of Enhancer, Promoter, Transcription (biology), Gene expression and DNA-binding protein.

What topics the last edition of the journal is best known for?

• Gene
• DNA
• Gene expression

The previous edition focused in particular on these issues:

The journal mostly deals with topics like Cell biology, Chromatin, Cancer research, Transcription factor and RNA. The studies on Cell biology discussed can also contribute to research in the domains of Enhancer, Transcription (biology), Gene expression, DNA and Epigenetics. Topics in Cancer research were tackled in line with various other fields like Cancer cell, Cancer, Metastasis, Carcinogenesis and KRAS.

While Transcription factor is the focus of Genes & Development, it also provided insights into the studies of Embryonic stem cell and Stem cell. In addition to RNA research, it aims to explore topics under Kinesin, Microtubule, MRNA transport and Binding site. The study of Gene, which falls within the realm of Genetics, was the main focus of the presentations.

The most cited articles from the last journal are:

• TFs for TEs: the transcription factor repertoire of mammalian transposable elements. (12 citations)
• Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks (11 citations)
• Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex (11 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

Top authors and change over time

The top authors publishing in Genes & Development (based on the number of publications) are:

• James L. Manley (54 papers) absent at the last edition,
• Danny Reinberg (48 papers) published 2 papers at the last edition,
• Ronald A. DePinho (38 papers) published 2 papers at the last edition,
• Robert Tjian (37 papers) absent at the last edition,
• Stephen J. Elledge (37 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Top affiliations and change over time

Only papers with recognized affiliations are considered

The top affiliations publishing in Genes & Development (based on the number of publications) are:

• Harvard University (703 papers) published 9 papers at the last edition, 3 more than at the previous edition,
• Howard Hughes Medical Institute (370 papers) published 5 papers at the last edition, 2 more than at the previous edition,
• University of California, San Francisco (279 papers) published 4 papers at the last edition the same number as at the previous edition,
• Massachusetts Institute of Technology (273 papers) published 3 papers at the last edition, 1 more than at the previous edition,
• National Institutes of Health (232 papers) published 8 papers at the last edition, 3 more than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2021 edition, 5.61% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 35.64% were posted by at least one author from the top 10 institutions publishing in the journal. Another 17.82% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 22.77% of all publications and 23.76% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

• Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
• Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
• Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
• Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
• Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.