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European Journal of Medicinal Chemistry
H-index 58

European Journal of Medicinal Chemistry

Ranking & Metrics

Discipline name Position Best Scientists Publications D-Index
Chemistry 96 499 985 54

Additional Metrics

Number of Best Scientists*: 1257
Documents by Best Scientists*: 1651
Top 100 Ranked Scientists*: 25
SCIMAGO H-index: 215
SCIMAGO SJR: 1.142
Impact Factor: 5.9

Overview

Top Research Topics at European Journal of Medicinal Chemistry?

The aim of the journal is to expand the discussion of research in Stereochemistry, Biochemistry, Chemical synthesis, Cytotoxicity and Structure–activity relationship. European Journal of Medicinal Chemistry holds forums on Stereochemistry that merges themes from other disciplines such as Biological activity and In vitro. Many of the studies tackled connect In vitro with a similar field of study like In vivo.

It connects the study in Biochemistry with the closely related area of Cancer cell. In addition to Chemical synthesis research, the journal aims to explore topics under Organic chemistry, Carboxamide and Antibacterial agent. While European Journal of Medicinal Chemistry focused on Antibacterial agent, it was also able to explore topics like Antibacterial activity and Antimicrobial.

The concepts on Cytotoxicity presented in European Journal of Medicinal Chemistry can also apply to other research fields, including Cell culture, HeLa and Cytotoxic T cell. The journal focuses on Structure–activity relationship but sometimes tackles the closely related topic of Pharmacology which is concerned with Receptor. The Apoptosis research presented in it explores the relationship between Cancer research and the closely related topic of Cancer.

  • Stereochemistry (47.78%)
  • Biochemistry (21.52%)
  • Chemical synthesis (16.39%)

What are the most cited papers published in the journal?

  • Biologically active dihydropyrimidones of the Biginelli-type--a literature survey. (1078 citations)
  • The role of antioxidants in the chemistry of oxidative stress: A review. (1029 citations)
  • A review of anti-infective and anti-inflammatory chalcones. (778 citations)

Research areas of the most cited articles at European Journal of Medicinal Chemistry:

The published articles mainly tackle studies in Stereochemistry, Chemical synthesis, Biochemistry, Antibacterial agent and Organic chemistry. The published papers hold forums on Stereochemistry that merge themes from other disciplines such as Biological activity, In vitro, Structure–activity relationship and Cytotoxicity. In addition to Chemical synthesis research, the published papers aim to explore topics under Bicyclic molecule, Medicinal chemistry, Enzyme inhibitor, In vivo and Carboxamide.

What topics the last edition of the journal is best known for?

  • Enzyme
  • Gene
  • Organic chemistry

The previous edition focused in particular on these issues:

The journal mainly tackles studies in In vivo, Cancer research, Structure–activity relationship, Cell growth and Moiety. Research in In vitro and the interrelating topic of Inhibitory effect, Derivative (chemistry) and Halogen were among the subjects of interest in the In vivo studies discussed in it. While Cancer research is the focus of European Journal of Medicinal Chemistry, it also provided insights into the studies of Cell cycle checkpoint, Cancer and Apoptosis.

Issues in Structure–activity relationship were discussed, taking into consideration concepts from other disciplines like Suzuki reaction, Macromolecule, Combinatorial chemistry, Divergent synthesis and Antifungal. The journal holds forums on Moiety that merges themes from other disciplines such as Indole test, Biochemistry, Kinase, Fibroblast and DNA replication. Pharmacophore research discussed in it aim to provide more information in the subject of Stereochemistry.

The most cited articles from the last journal are:

  • Facile and divergent optimization of chromazonarol enabled the identification of simplified drimane meroterpenoids as novel pharmaceutical leads. (0 citations)
  • Positioning of an unprecedented 1,5-oxaza spiroquinone scaffold into SMYD2 inhibitors in epigenetic space. (0 citations)
  • Design, synthesis, and mechanistic investigations of phenylalanine derivatives containing a benzothiazole moiety as HIV-1 capsid inhibitors with improved metabolic stability. (0 citations)

Papers citation over time

A key indicator for each journal is its effectiveness in reaching other researchers with the papers published at that venue.

The chart below presents the interquartile range (first quartile 25%, median 50% and third quartile 75%) of the number of citations of articles over time.

The top authors publishing in European Journal of Medicinal Chemistry (based on the number of publications) are:

  • Claudiu T. Supuran (109 papers) absent at the last edition,
  • Jan Balzarini (69 papers) absent at the last edition,
  • Hong-Min Liu (66 papers) absent at the last edition,
  • Erik De Clercq (65 papers) published 1 paper at the last edition, 5 less than at the previous edition,
  • Ettore Novellino (57 papers) absent at the last edition.

The overall trend for top authors publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top authors.

Only papers with recognized affiliations are considered

The top affiliations publishing in European Journal of Medicinal Chemistry (based on the number of publications) are:

  • Chinese Academy of Sciences (320 papers) absent at the last edition,
  • China Pharmaceutical University (308 papers) absent at the last edition,
  • Centre national de la recherche scientifique (238 papers) absent at the last edition,
  • Rega Institute for Medical Research (205 papers) published 1 paper at the last edition, 14 less than at the previous edition,
  • Shenyang Pharmaceutical University (186 papers) published 2 papers at the last edition, 22 less than at the previous edition.

The overall trend for top affiliations publishing in this journal is outlined below. The chart shows the number of publications at each edition of the journal for top affiliations.

Publication chance based on affiliation

The publication chance index shows the ratio of articles published by the best research institutions in the journal edition to all articles published within that journal. The best research institutions were selected based on the largest number of articles published during all editions of the journal.

The chart below presents the percentage ratio of articles from top institutions (based on their ranking of total papers).Top affiliations were grouped by their rank into the following tiers: top 1-10, top 11-20, top 21-50, and top 51+. Only articles with a recognized affiliation are considered.

During the most recent 2022 edition, 0.00% of publications had an unrecognized affiliation. Out of the publications with recognized affiliations, 26.67% were posted by at least one author from the top 10 institutions publishing in the journal. Another 0.00% included authors affiliated with research institutions from the top 11-20 affiliations. Institutions from the 21-50 range included 0.00% of all publications and 73.33% were from other institutions.

Returning Authors Index

A very common phenomenon observed among researchers publishing scientific articles is the intentional selection of journals they have already attended in the past. In particular, it is worth analyzing the case when the authors participate in the same journal from year to year.

The Returning Authors Index presented below illustrates the ratio of authors who participated in both a given as well as the previous edition of the journal in relation to all participants in a given year.

Returning Institution Index

The graph below shows the Returning Institution Index, illustrating the ratio of institutions that participated in both a given and the previous edition of the conference in relation to all affiliations present in a given year.

The experience to innovation index

Our experience to innovation index was created to show a cross-section of the experience level of authors publishing in a journal. The index includes the authors publishing at the last edition of a journal, grouped by total number of publications throughout their academic career (P) and the total number of citations of these publications ever received (C).

The group intervals were selected empirically to best show the diversity of the authors' experiences, their labels were selected as a convenience, not as judgment. The authors were divided into the following groups:

  • Novice - P < 5 or C < 25 (the number of publications less than 5 or the number of citations less than 25),
  • Competent - P < 10 or C < 100 (the number of publications less than 10 or the number of citations less than 100),
  • Experienced - P < 25 or C < 625 (the number of publications less than 25 or the number of citations less than 625),
  • Master - P < 50 or C < 2500 (the number of publications less than 50 or the number of citations less than 2500),
  • Star - P ≥ 50 and C ≥ 2500 (both the number of publications greater than 50 and the number of citations greater than 2500).

The chart below illustrates experience levels of first authors in cases of publications with multiple authors.

Top Publications

  • β-lactam antibiotics: An overview from a medicinal chemistry perspective.

    Lidia Moreira Lima;Bianca Nascimento Monteiro da Silva;Gisele Barbosa;Eliezer J. Barreiro

    (2020)
    544 Citations
  • Alzheimer's disease and its treatment by different approaches: A review.

    Sukriti Srivastava;Razi Ahmad;Sunil Kumar Khare

    (2021)
    427 Citations
  • Recent developments of gallic acid derivatives and their hybrids in medicinal chemistry: A review

    Nourah A. Al Zahrani;Reda M. El-Shishtawy;Abdullah M. Asiri

    (2020)
    330 Citations
  • hERG toxicity assessment: Useful guidelines for drug design.

    Amanda Garrido;Alban Lepailleur;Serge M. Mignani;Patrick Dallemagne

    (2020)
    303 Citations
  • Bioactive pyrrole-based compounds with target selectivity.

    Giovanna Li Petri;Virginia Spanò;Roberto Spatola;Ralph Holl

    (2020)
    227 Citations
  • Applications of fluorine-containing amino acids for drug design.

    Haibo Mei;Jianlin Han;Karel D. Klika;Kunisuke Izawa

    (2020)
    225 Citations
  • Antibacterial activities with the structure-activity relationship of coumarin derivatives

    Hua-Li Qin;Zai-Wei Zhang;Lekkala Ravindar;K.P. Rakesh

    (2020)
    210 Citations
  • Indole-based derivatives as potential antibacterial activity against methicillin-resistance Staphylococcus aureus (MRSA).

    Hua-Li Qin;Jing Liu;Wan-Yin Fang;L. Ravindar

    (2020)
    182 Citations
  • Recent advances in biological activities of rhodium complexes: Their applications in drug discovery research.

    Marzieh Sohrabi;Mina Saeedi;Bagher Larijani;Mohammad Mahdavi

    (2021)
    174 Citations
  • Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review.

    Hua-Li Qin;Zai-Wei Zhang;Ravindar Lekkala;Hamed Alsulami

    (2020)
    167 Citations

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