His main research concerns Cell biology, Reactive oxygen species, Signal transduction, PI3K/AKT/mTOR pathway and Protein kinase B. His Cell biology research incorporates elements of Cell cycle and Apoptosis. His Reactive oxygen species research includes elements of Molecular biology and Superoxide dismutase.
His research investigates the connection between Molecular biology and topics such as Protein kinase A that intersect with issues in MAPK/ERK pathway and Cell growth. Zhuo Zhang focuses mostly in the field of Signal transduction, narrowing it down to matters related to Carcinogenesis and, in some cases, Cancer prevention and Pharmacology. His PI3K/AKT/mTOR pathway research is multidisciplinary, incorporating perspectives in Cancer research, Angiogenesis and Transfection.
Carcinogenesis, Cell biology, Cancer research, Reactive oxygen species and Molecular biology are his primary areas of study. His Carcinogenesis study combines topics in areas such as Autophagy, Malignant transformation, Signal transduction and Carcinogen. Zhuo Zhang interconnects Apoptosis, Cell and Vanadate in the investigation of issues within Cell biology.
His Cancer research research includes themes of Protein kinase B, PI3K/AKT/mTOR pathway, Immunology and Internal medicine. His studies deal with areas such as Oxidative stress, SOD2, Superoxide dismutase and Catalase as well as Reactive oxygen species. His work deals with themes such as Cell culture, Cell signaling, Cell growth and Environmental exposure, which intersect with Molecular biology.
Zhuo Zhang mainly focuses on Carcinogenesis, Cancer research, Carcinogen, Reactive oxygen species and Cancer. Zhuo Zhang combines subjects such as Autophagy, Malignant transformation, Cell growth and Cell biology with his study of Carcinogenesis. His Cell biology study combines topics from a wide range of disciplines, such as Apoptosis and Cadmium.
His Cancer research study also includes
His primary areas of investigation include Carcinogenesis, Cancer research, Carcinogen, Reactive oxygen species and Malignant transformation. As a member of one scientific family, Zhuo Zhang mostly works in the field of Carcinogenesis, focusing on Cell and, on occasion, STAT3 and Gene knockdown. The Cancer research study combines topics in areas such as Colorectal cancer, In vitro, Immunology and NEDD9.
The research on Cell biology and Biochemistry is part of his Reactive oxygen species project. His Cell biology study frequently draws parallels with other fields, such as Oxidative stress. His research on Malignant transformation also deals with topics like
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G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
Ning Gao;Daniel C. Flynn;Zhuo Zhang;Xiao-Song Zhong.
American Journal of Physiology-cell Physiology (2004)
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
Bach Cuc Nguyen;Karine Lefort;Anna Mandinova;Dario Antonini.
Genes & Development (2006)
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer.
Ning Gao;Zhuo Zhang;Bing-Hua Jiang;Bing-Hua Jiang;Xianglin Shi.
Biochemical and Biophysical Research Communications (2003)
Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways.
Poyil Pratheeshkumar;Amit Budhraja;Young-Ok Son;Xin Wang.
PLOS ONE (2012)
Vanadate-induced Expression of Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor through Phosphatidylinositol 3-Kinase/Akt Pathway and Reactive Oxygen Species
Ning Gao;Min Ding;Jenny Z. Zheng;Zhuo Zhang.
Journal of Biological Chemistry (2002)
Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis
Chuanshu Huang;Zhuo Zhang;Min Ding;Jingxia Li.
Journal of Biological Chemistry (2000)
Cancer Prevention with Promising Natural Products: Mechanisms of Action and Molecular Targets
Poyil Pratheeshkumar;Chakkenchath Sreekala;Zhuo Zhang;Amit Budhraja.
Anti-cancer Agents in Medicinal Chemistry (2012)
Vanadate-induced cell growth regulation and the role of reactive oxygen species.
Zhuo Zhang;Chuanshu Huang;Jingxia Li;Stephen S. Leonard.
Archives of Biochemistry and Biophysics (2001)
p38 Signaling-mediated Hypoxia-inducible Factor 1α and Vascular Endothelial Growth Factor Induction by Cr(VI) in DU145 Human Prostate Carcinoma Cells
Ning Gao;Bing-Hua Jiang;Stephen S. Leonard;Linda Corum.
Journal of Biological Chemistry (2002)
Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest
Zhuo Zhang;Zhuo Zhang;Stephen S Leonard;Stephen S Leonard;Chuanshu Huang;Val Vallyathan.
Free Radical Biology and Medicine (2003)
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