What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Biochemistry, Enzyme, Alcohol dehydrogenase, Isozyme and Ethanol metabolism.
All of his Biochemistry and Carboxylesterase and Isoelectric focusing investigations are sub-components of the entire Biochemistry study.
His work deals with themes such as Zinc, Metal and Phosphate, which intersect with Enzyme.
His Alcohol dehydrogenase study incorporates themes from Proteomics, Quantitative proteomics, Branched-chain alpha-keto acid dehydrogenase complex, ADH1B and NAD+ kinase.
His Isozyme research focuses on subjects like Gene, which are linked to Hydrolase, Molecular biology and Topoisomerase.
His Ethanol metabolism research incorporates themes from ALDH2, Aldehyde dehydrogenase and Acetaldehyde.
His most cited work include:
- Purification and characterization of a human liver cocaine carboxylesterase that catalyzes the production of benzoylecgonine and the formation of cocaethylene from alcohol and cocaine. (140 citations)
- Human liver alcohol dehydrogenase: purification and kinetic characterization of the beta 2 beta 2, beta 2 beta 1, alpha beta 2, and beta 2 gamma 1 "Oriental" isoenzymes. (128 citations)
- Catalytic properties of human liver alcohol dehydrogenase isoenzymes. (111 citations)
What are the main themes of his work throughout his whole career to date?
William F. Bosron spends much of his time researching Biochemistry, Alcohol dehydrogenase, Ethanol, Enzyme and Isozyme.
His Biochemistry study frequently draws connections between related disciplines such as Molecular biology.
His Alcohol dehydrogenase research includes elements of Amino acid, NAD+ kinase, Coenzyme binding and Stereochemistry.
He focuses mostly in the field of Ethanol, narrowing it down to matters related to Internal medicine and, in some cases, Enzyme assay.
His Enzyme research is multidisciplinary, incorporating perspectives in Alpha, Metal and Magnesium.
In his work, Allele is strongly intertwined with Protein subunit, which is a subfield of Isozyme.
He most often published in these fields:
- Biochemistry (66.29%)
- Alcohol dehydrogenase (57.30%)
- Ethanol (35.96%)
What were the highlights of his more recent work (between 2001-2010)?
- Biochemistry (66.29%)
- Carboxylesterase (14.61%)
- Isozyme (29.21%)
In recent papers he was focusing on the following fields of study:
Biochemistry, Carboxylesterase, Isozyme, Formaldehyde dehydrogenase and Stereochemistry are his primary areas of study.
His Biochemistry study frequently links to adjacent areas such as Hepatic stellate cell.
His Carboxylesterase study is related to the wider topic of Enzyme.
His Enzyme research is multidisciplinary, incorporating elements of Metabolite, Prodrug and Hydrolysis.
William F. Bosron combines subjects such as Molecular biology, Peptide, Alcohol dehydrogenase and Mass spectrometry with his study of Isozyme.
He has included themes like Cofactor and Active site in his Formaldehyde dehydrogenase study.
Between 2001 and 2010, his most popular works were:
- Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis. (106 citations)
- HYDROLYSIS OF IRINOTECAN AND ITS OXIDATIVE METABOLITES, 7-ETHYL-10-[4-N-(5-AMINOPENTANOIC ACID)-1-PIPERIDINO] CARBONYLOXYCAMPTOTHECIN AND 7-ETHYL-10-[4-(1-PIPERIDINO)-1-AMINO]-CARBONYLOXYCAMPTOTHECIN, BY HUMAN CARBOXYLESTERASES CES1A1, CES2, AND A NEWLY EXPRESSED CARBOXYLESTERASE ISOENZYME, CES3 (105 citations)
- A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme. (92 citations)
In his most recent research, the most cited papers focused on:
William F. Bosron focuses on Biochemistry, Isozyme, Carboxylesterase, Enzyme and Gene expression.
His research in the fields of Alcohol dehydrogenase, Peptide and Label-free quantification overlaps with other disciplines such as Selected reaction monitoring.
His work carried out in the field of Isozyme brings together such families of science as Proteomics and Quantitative proteomics.
His Carboxylesterase research includes themes of Thioester, Metabolite, Prodrug, Hydrolysis and Stereochemistry.
His Enzyme research is mostly focused on the topic Enzyme inhibitor.
The various areas that William F. Bosron examines in his Gene expression study include Hydrolase, Molecular biology and Topoisomerase.
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