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Biology and Biochemistry

D-Index
64
Citations
60888
World Ranking
9424
National Ranking
4153

Overview

Vladimir Makarov is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on medicine, with significant contributions in oncology, pulmonary and respiratory medicine, immunology, surgery, and cancer research.

The scientist's work spans several key topics in cancer biology and treatment, including:

  • Cancer Immunotherapy and Biomarkers
  • Renal Cell Carcinoma Treatment
  • Ferroptosis and Cancer Prognosis
  • Salivary Gland Tumors Diagnosis and Treatment
  • Immunotherapy and Immune Responses
  • CAR-T Cell Therapy Research
  • Cancer Genomics and Diagnostics

Among their recent publications are studies addressing immune landscapes, tumor biology, and genomic drivers in various cancers. Notable papers include:

  • "Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy," 2021, Cancer Cell
  • "The Immune Microenvironment and Neoantigen Landscape of Aggressive Salivary Gland Carcinomas Differ by Subtype," 2020, Clinical Cancer Research
  • "Comprehensive Genomic Analysis of Translocation Renal Cell Carcinoma Reveals Copy-Number Variations as Drivers of Disease Progression," 2020, Clinical Cancer Research
  • "H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer," 2022, Proceedings of the National Academy of Sciences
  • "KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer," 2023, Cancer Research

Makarov has frequently published in journals including:

  • Clinical Cancer Research
  • Nature Medicine
  • OncoImmunology
  • Journal of Clinical Oncology
  • Laryngo-Rhino-Otologie

The scientist has collaborated extensively with peers such as Timothy A. Chan, Fengshen Kuo, Diego Chowell, Luc G.T. Morris, and A. Ari Hakimi. These collaborations have contributed to a multidisciplinary approach to cancer research and immunology.

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer

    Naiyer A. Rizvi;Naiyer A. Rizvi;Matthew D. Hellmann;Matthew D. Hellmann;Alexandra Snyder;Alexandra Snyder;Pia Kvistborg

  • Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

    Alexandra Snyder;Vladimir Makarov;Taha Merghoub;Jianda Yuan

  • Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

    Nicholas McGranahan;Nicholas McGranahan;Andrew J. S. Furness;Rachel Rosenthal;Sofie Ramskov

  • Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.

    Nadeem Riaz;Jonathan J. Havel;Vladimir Makarov;Alexis Desrichard

  • Patterns and rates of exonic de novo mutations in autism spectrum disorders

    Benjamin M. Neale;Yan Kou;Li Liu;Avi Ma'Ayan

  • Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

    Katherine B. Chiappinelli;Pamela L. Strissel;Alexis Desrichard;Huili Li

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

    Vinod P. Balachandran;Marta Łuksza;Julia N. Zhao;Vladimir Makarov

  • Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

    Diego Chowell;Luc G. T. Morris;Claud M. Grigg;Jeffrey K. Weber

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Microduplications of 16p11.2 are Associated with Schizophrenia

    Shane E. McCarthy;Vladimir Makarov;George Kirov;Anjene M. Addington

  • Sensitive and accurate detection of copy number variants using read depth of coverage

    Seungtai Yoon;Zhenyu Xuan;Vladimir Makarov;Kenny Ye

  • A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

    Marta Łuksza;Nadeem Riaz;Vladimir Makarov;Vinod P. Balachandran

  • A map of human genome variation from population-scale sequencing

    Richard M. Durbin;David L. Altshuler;Gonçalo R. Abecasis;David R. Bentley

  • Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response

    Rajarsi Mandal;Rajarsi Mandal;Robert M. Samstein;Ken Wing Lee;Jonathan J. Havel

  • Solvation and hydration of proteins and nucleic acids: a theoretical view of simulation and experiment.

    Vladimir Makarov;B. Montgomery Pettitt;Michael Feig

  • Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

    Vladimir Vacic;Vladimir Vacic;Shane McCarthy;Dheeraj Malhotra;Dheeraj Malhotra;Fiona Murray

  • Erratum: Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses (Cell (2015) 152 (974-986))

    Katherine B. Chiappinelli;Pamela L. Strissel;Alexis Desrichard;Huili Li

  • Abstract B32: Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses

    Katherine B. Chiappinelli;Pamela L. Strissel;Alexis Desrichard;Huili Li

Frequent Co-Authors

Timothy A. Chan
Timothy A. Chan Cleveland Clinic
Jedd D. Wolchok
Jedd D. Wolchok Cornell University
Luc G. T. Morris
Luc G. T. Morris Memorial Sloan Kettering Cancer Center
Taha Merghoub
Taha Merghoub Cornell University
Joseph D. Buxbaum
Joseph D. Buxbaum Icahn School of Medicine at Mount Sinai
Jonathan Sebat
Jonathan Sebat University of California, San Diego
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Matthew D. Hellmann
Matthew D. Hellmann Memorial Sloan Kettering Cancer Center
Naiyer A. Rizvi
Naiyer A. Rizvi Columbia University Medical Center
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston

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