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Tzu-Ping Ko

Tzu-Ping Ko

D-Index & Metrics

Chemistry

D-Index
52
Citations
9615
World Ranking
13513
National Ranking
99

Overview

Tzu-Ping Ko is affiliated with Academia Sinica in Taiwan and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans several subfields including Molecular Biology, Materials Chemistry, Pharmacology, Organic Chemistry, and Plant Science.

Their research topics cover a range of scientific areas, notably:

  • Enzyme Structure and Function
  • Biochemical and Molecular Research
  • Glycosylation and Glycoproteins Research
  • Plant Biochemistry and Biosynthesis
  • Bacteriophages and Microbial Interactions
  • Carbohydrate Chemistry and Synthesis
  • Microbial Natural Products and Biosynthesis

Tzu-Ping Ko has published in several frequent scientific venues, including:

  • Nature Communications
  • Biochemical and Biophysical Research Communications
  • Journal of Biomedical Science
  • Journal of Biological Chemistry
  • Nucleic Acids Research

Significant recent publications include:

  • Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans (2020) in Proceedings of the National Academy of Sciences
  • Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase (2020) in Nature Communications
  • Structural basis of polyethylene glycol recognition by antibody (2020) in Journal of Biomedical Science
  • Crystal structure and functional implication of bacterial STING (2022) in Nature Communications
  • Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use (2022) in Journal of Biomedical Science

The scientist collaborates frequently with several coauthors, including:

  • Kai-Fa Huang (10 publications)
  • Yuan-Chih Chang (5 publications)
  • Kuen-Phon Wu (4 publications)
  • Shang-Te Danny Hsu (4 publications)
  • Rey-Ting Guo (4 publications)

Best Publications

  • Structure, mechanism and function of prenyltransferases

    Po-Huang Liang;Tzu-Ping Ko;Andrew H.-J Wang

  • Structural insight into catalytic mechanism of PET hydrolase

    Xu Han;Weidong Liu;Jian-Wen Huang;Jiantao Ma;Jiantao Ma

  • Mechanism of the Maturation Process of SARS-CoV 3CL Protease

    Min-Feng Hsu;Chih-Jung Kuo;Kai-Ti Chang;Kai-Ti Chang;Hui-Chuan Chang

  • The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein

    Tzu Ping Ko;Chen Chung Liao;Wen Yen Ku;Kin Fu Chak

  • Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases

    Rey Ting Guo;Rong Cao;Po Huang Liang;Po Huang Liang;Tzu Ping Ko

  • Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds

    Cheng Chung Lee;Cheng Chung Lee;Chih Jung Kuo;Tzu Ping Ko;Min Feng Hsu

  • Crystal Structures of Undecaprenyl Pyrophosphate Synthase in Complex with Magnesium, Isopentenyl Pyrophosphate, and Farnesyl Thiopyrophosphate ROLES OF THE METAL ION AND CONSERVED RESIDUES IN CATALYSIS

    Rey-Ting Guo;Tzu-Ping Ko;Annie P.-C. Chen;Annie P.-C. Chen;Chih-Jung Kuo

  • Structural studies reveal the molecular mechanism of PETase

    Chun-Chi Chen;Xu Han;Tzu-Ping Ko;Weidong Liu;Weidong Liu

  • Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.

    Han-Yu Sun;Sheng-Wei Lin;Sheng-Wei Lin;Tzu-Ping Ko;Jia-Fu Pan

  • Terpyridine-platinum(II) complexes are effective inhibitors of mammalian topoisomerases and human thioredoxin reductase 1.

    Yan-Chung Lo;Tzu-Ping Ko;Wen-Chi Su;Tsann-Long Su

  • The Three-Dimensional Structure of Canavalin from Jack Bean (Canavalia ensiformis)

    Tzu-Ping Ko;J. D. Ng;A. Mcpherson

  • Crystal structure of yeast cytosine deaminase. Insights into enzyme mechanism and evolution

    Tzu Ping Ko;Jing Jer Lin;Chih Yung Hu;Yi Hsin Hsu

  • Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation

    Kai-Fa Huang;Yi-Liang Liu;Wei-Ju Cheng;Tzu-Ping Ko

  • Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation

    Tao-Hsin Chang;Tao-Hsin Chang;Fu-Lien Hsieh;Fu-Lien Hsieh;Tzu-Ping Ko;Kuo-Hsun Teng;Kuo-Hsun Teng

  • Structures of three crystal forms of the sweet protein thaumatin.

    T.-P. Ko;J. Day;A. Greenwood;A. McPherson

  • Mechanism of product chain length determination and the role of a flexible loop in Escherichia coli undecaprenyl-pyrophosphate synthase catalysis.

    Tzu-Ping Ko;Yi-Kai Chen;Howard Robinson;Pei-Chun Tsai

  • Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase.

    Faik N. Musayev;Martino L. Di Salvo;Tzu Ping Ko;Verne Schirch

  • Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: implications in virion assembly and immunogenicity.

    Cheng-Chung Lee;Tzu-Ping Ko;Chia-Cheng Chou;Masato Yoshimura

  • Crystal Structure of Type-III Geranylgeranyl Pyrophosphate Synthase from Saccharomyces cerevisiae and the Mechanism of Product Chain Length Determination

    Tao-Hsin Chang;Rey-Ting Guo;Tzu-Ping Ko;Andrew H.-J. Wang;Andrew H.-J. Wang

  • Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.

    Yu Ming Chang;Wen Yih Jeng;Tzu Ping Ko;Yao Jen Yeh

  • Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans.

    Tzu Jing Yang;Tzu Jing Yang;Yen Chen Chang;Yen Chen Chang;Tzu Ping Ko;Piotr Draczkowski

  • The Refined Crystal Structure of an Eel Pout Type III Antifreeze Protein RD1 at 0.62-Å Resolution Reveals Structural Microheterogeneity of Protein and Solvation

    Tzu Ping Ko;Howard Robinson;Yi Gui Gao;Chi Hing C. Cheng

Frequent Co-Authors

Andrew H.-J. Wang
Andrew H.-J. Wang Academia Sinica
Po-Huang Liang
Po-Huang Liang Academia Sinica
Eric Oldfield
Eric Oldfield University of Illinois at Urbana-Champaign
Yanhe Ma
Yanhe Ma Chinese Academy of Sciences
Alexander McPherson
Alexander McPherson University of California, Irvine
Chu Fang Lo
Chu Fang Lo National Cheng Kung University
Jei-Fu Shaw
Jei-Fu Shaw I-Shou University
Shih-Hsiung Wu
Shih-Hsiung Wu University of Wisconsin--Madison
Shin-Ru Shih
Shin-Ru Shih Chang Gung University
Juergen Wiegel
Juergen Wiegel University of Georgia

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