Tomoaki Shirao

Best Publications

• Role of actin cytoskeleton in dendritic spine morphogenesis.

  Yuko Sekino;Nobuhiko Kojima;Tomoaki Shirao

  407
  Citations

• Modulatory Role of Drebrin on the Cytoskeleton within Dendritic Spines in the Rat Cerebral Cortex

  Kensuke Hayashi;Ryoki Ishikawa;Li-Hong Ye;Xiao-Ling He

  304
  Citations

• AMPA receptor downscaling at the onset of Alzheimer’s disease pathology in double knockin mice

  Eric H. Chang;Mary J. Savage;Dorothy G. Flood;Justin M. Thomas

  292
  Citations

• Change in the shape of dendritic spines caused by overexpression of drebrin in cultured cortical neurons.

  Kensuke Hayashi;Tomoaki Shirao

  287
  Citations

• Drebrin-dependent actin clustering in dendritic filopodia governs synaptic targeting of postsynaptic density-95 and dendritic spine morphogenesis.

  Hideto Takahashi;Yuko Sekino;Satoshi Tanaka;Toshiyuki Mizui

  277
  Citations

• Loss of proteins regulating synaptic plasticity in normal aging of the human brain and in Alzheimer disease.

  Kimmo J Hatanpaa;Krystyna R. Isaacs;Tomoaki Shirao;Daniel R. Brady

  270
  Citations

• DREBRIN, A DEVELOPMENT-ASSOCIATED BRAIN PROTEIN FROM RAT EMBRYO, CAUSES THE DISSOCIATION OF TROPOMYOSIN FROM ACTIN FILAMENTS

  R. Ishikawa;K. Hayashi;T. Shirao;Yinhuan Xue

  246
  Citations

• Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease.

  Y. Harigaya;M. Shoji;T. Shirao;S. Hirai

  226
  Citations

• Interactions of drebrin and gephyrin with profilin.

  Akiko Mammoto;Takuya Sasaki;Takeshi Asakura;Ikuko Hotta

  208
  Citations

• Drebrin A is a postsynaptic protein that localizes in vivo to the submembranous surface of dendritic sites forming excitatory synapses

  Chiye Aoki;Yuko Sekino;Kenji Hanamura;Sho Fujisawa

  147
  Citations

• Synaptic dysfunction and disruption of postsynaptic drebrin-actin complex : A study of neurological disorders accompanied by cognitive deficits

  Nobuhiko Kojima;Tomoaki Shirao

  143
  Citations

• Immunochemical homology of 3 developmentally regulated brain proteins and their developmental change in neuronal distribution

  Tomoaki Shirao;Kunihiko Obata

  139
  Citations

• Drebrin A regulates dendritic spine plasticity and synaptic function in mature cultured hippocampal neurons.

  Anton Ivanov;Monique Esclapez;Christophe Pellegrino;Tomoaki Shirao

  138
  Citations

• Actin filaments and microtubules in dendritic spines

  Tomoaki Shirao;Christian González-Billault

  123
  Citations

• Two acidic proteins associated with brain development in chick embryo.

  Tomoaki Shirao;Kunihiko Obata

  118
  Citations

• Down-regulation of drebrin A expression suppresses synaptic targeting of NMDA receptors in developing hippocampal neurones.

  Hideto Takahashi;Toshiyuki Mizui;Tomoaki Shirao

  116
  Citations

• Identification of a synaptic vesicle-specific 38,000-dalton protein by monoclonal antibodies.

  Kunihiko Obata;Hiroshi Nishiye;Hiroshi Nishiye;Shinobu C. Fujita;Tomoaki Shirao

  115
  Citations

• Clustering and anchoring mechanisms of molecular constituents of postsynaptic scaffolds in dendritic spines.

  Tomoaki Shirao;Yuko Sekino

  103
  Citations

• Overexpression of drebrin A in immature neurons induces the accumulation of F-actin and PSD-95 into dendritic filopodia, and the formation of large abnormal protrusions.

  Toshiyuki Mizui;Hideto Takahashi;Yuko Sekino;Tomoaki Shirao

  100
  Citations

• High level of adenosine A1 receptor-like immunoreactivity in the CA2/CA3a region of the adult rat hippocampus.

  T. Ochiishi;Y. Saitoh;A. Yukawa;M. Saji

  95
  Citations