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Genetics

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Overview

Terri L. Young is affiliated with the University of Wisconsin-Madison in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant emphasis on ophthalmology and genetic factors related to ocular diseases.

The scientist's work covers various subfields including Ophthalmology, Molecular Biology, Genetics, Epidemiology, and Radiology, Nuclear Medicine and Imaging. The main topics addressed in their research include:

  • Glaucoma and retinal disorders
  • Retinal diseases and treatments
  • Genetic associations and epidemiology
  • Ophthalmology and visual impairment studies
  • Corneal surgery and disorders
  • Retinal development and disorders
  • Biomedical text mining and ontologies

Terri L. Young has contributed to several publications, with recent notable papers including:

  • Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries, 2021, Nature Communications
  • Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies, 2021, Nature Communications
  • Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci, 2023, Nature Genetics
  • SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma, 2020, Investigative Ophthalmology & Visual Science
  • Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank, 2021, Ophthalmology

The scientist frequently publishes in venues such as Nature Communications, Investigative Ophthalmology & Visual Science, JAMA Ophthalmology, bioRxiv (Cold Spring Harbor Laboratory), and UNC Libraries.

Terri L. Young collaborates regularly with multiple coauthors, among whom the most frequent are:

  • David A. Mackey
  • Alex W. Hewitt
  • Jamie E. Craig
  • Puya Gharahkhani
  • Ching-Yu Cheng

Best Publications

  • Outdoor activity and myopia in Singapore teenage children

    Mohamed Dirani;Louis Tong;Gus Gazzard;Xiaoe Zhang

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

    Virginie J M Verhoeven;Pirro G Hysi;Robert Wojciechowski;Robert Wojciechowski;Qiao Fan

  • Multicenter trial of Cryotherapy for Retinopathy of Prematurity: Ophthalmological outcomes at 10 years

    F. J. Elsas;M. Collins;J. Jones;J. A. Kimble

  • Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

    Gudmar Thorleifsson;G Bragi Walters;Alex W Hewitt;Alex W Hewitt;Gisli Masson

  • Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

    Norihiro Kato;Marie Loh;Marie Loh;Marie Loh;Fumihiko Takeuchi;Niek Verweij

  • Methodology of the Singapore Indian Chinese Cohort (SICC) Eye Study: Quantifying ethnic variations in the epidemiology of eye diseases in Asians

    R Lavanya;Vse Jeganathan;YF Zheng;P Raju

  • Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

    Yi Lu;Veronique Vitart;Kathryn P. Burdon;Chiea Chuen Khor

  • Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

    Y. Okada;X. Sim;X. Sim;M. J. Go;J. Y. Wu;J. Y. Wu

  • A second locus for familial high myopia maps to chromosome 12q

    Terri L. Young;Shawn M. Ronan;Alison B. Alvear;Scott C. Wildenberg

  • Evidence that a locus for familial high myopia maps to chromosome 18p

    Terri L. Young;Shawn M. Ronan;Leslie A. Drahozal;Scott C. Wildenberg

  • The cardiofaciocutaneous syndrome

    Amy Roberts;Judith Allanson;Suzanne K Jadico;Maria Ines Kavamura

  • Prevalence of amblyopia and strabismus in young singaporean chinese children.

    Audrey Chia;Mohamed Dirani;Yiong Huak Chan;Gus Gazzard

  • Complex trait genetics of refractive error.

    Terri L. Young;Ravikanth Metlapally;Amanda E. Shay

  • Prevalence of Refractive Error in Singaporean Chinese Children: The Strabismus, Amblyopia, and Refractive Error in Young Singaporean Children (STARS) Study

    Mohamed Dirani;Yiong-Huak Chan;Gus Gazzard;Dana Marie Hornbeak

  • Chloride Channel ClCN7 Mutations Are Responsible for Severe Recessive, Dominant, and Intermediate Osteopetrosis

    Annalisa Frattini;Alessandra Pangrazio;Lucia Susani;Cristina Sobacchi

  • New locus for autosomal dominant high myopia maps to the long arm of chromosome 17.

    Prasuna Paluru;Shawn M Ronan;Elise Heon;Marcella Devoto;Marcella Devoto

  • A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25

    Pirro G Hysi;Terri L Young;David A Mackey;David A Mackey;Toby Andrew

  • A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.

    Abbas M Solouki;Virginie J M Verhoeven;Cornelia M van Duijn;Annemieke J M H Verkerk

  • Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

    Pirro G Hysi;Ching-Yu Cheng;Henriët Springelkamp;Stuart Macgregor

Frequent Co-Authors

David A. Mackey
David A. Mackey University of Western Australia
Tien Yin Wong
Tien Yin Wong Tsinghua University
Alex W. Hewitt
Alex W. Hewitt University of Tasmania
Christopher J. Hammond
Christopher J. Hammond King's College London
Seang-Mei Saw
Seang-Mei Saw National University of Singapore
Tin Aung
Tin Aung National University of Singapore
Pirro G. Hysi
Pirro G. Hysi King's College London
Ching-Yu Cheng
Ching-Yu Cheng National University of Singapore
Stuart MacGregor
Stuart MacGregor QIMR Berghofer Medical Research Institute
Chiea Chuen Khor
Chiea Chuen Khor Agency for Science, Technology and Research

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