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Biology and Biochemistry

D-Index
76
Citations
49460
World Ranking
4914
National Ranking
2359

Medicine

D-Index
77
Citations
49608
World Ranking
18229
National Ranking
9091

Overview

Steven R. Brant is affiliated with Rutgers, The State University of New Jersey in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Genetics, Surgery, Epidemiology, Immunology, and Molecular Biology as subfields of study.

The main topics covered in their work include Inflammatory Bowel Disease, Microscopic Colitis, Helicobacter pylori-related gastroenterology studies, Autoimmune and Inflammatory Disorders, Immunodeficiency and Autoimmune Disorders, Eosinophilic Esophagitis, and Diverticular Disease and Complications.

The scientist has published extensively in several venues, with frequent publications appearing in:

  • Gastroenterology
  • Inflammatory Bowel Diseases
  • UNC Libraries
  • Journal of Crohn's and Colitis
  • Clinical Gastroenterology and Hepatology

Notable recent papers authored or co-authored by Steven R. Brant include:

  • A genomic mutational constraint map using variation in 76,156 human genomes, 2023, Nature
  • Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries, 2023, Nature Genetics
  • Author Correction: A genomic mutational constraint map using variation in 76,156 human genomes, 2024, Nature
  • Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target, 2021, Gastroenterology
  • Common and Rare Variant Prediction and Penetrance of IBD in a Large, Multi-ethnic, Health System-based Biobank Cohort, 2020, Gastroenterology

The scientist collaborates frequently with other researchers, including Judy H. Cho, Dermot McGovern, John D. Rioux, Richard H. Duerr, and Mark S. Silverberg.

Best Publications

  • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

    Yasunori Ogura;Denise K. Bonen;Naohiro Inohara;Dan L. Nicolae

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

    Mark S. Silverberg;Jack Satsangi;Tariq Ahmad;Ian D. R. Arnott

  • A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

    Richard H. Duerr;Kent D. Taylor;Steven R. Brant;Steven R. Brant;John D. Rioux;John D. Rioux

  • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

    Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

    John D. Rioux;John D. Rioux;Ramnik J. Xavier;Kent D. Taylor;Mark S. Silverberg

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease.

    Manuel A. Rivas;Manuel A. Rivas;Manuel A. Rivas;Mélissa Beaudoin;Agnes Gardet;Christine Stevens

  • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease.

    Steven A McCarroll;Alan Huett;Petric Kuballa;Shannon D Chilewski

  • Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

    Isabelle Cleynen;Isabelle Cleynen;Gabrielle Boucher;Luke Jostins;Luke Jostins;Luke Jostins;L Philip Schumm

  • Genome-wide association identifies multiple ulcerative colitis susceptibility loci

    Dermot P.B. McGovern;Agnès Gardet;Leif Törkvist;Philippe Goyette

  • MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α

    Feng Wu;Michelle Zikusoka;Anil Trindade;Themistocles Dassopoulos

  • Recent Insights Into the Genetics of Inflammatory Bowel Disease

    Judy H. Cho;Steven R. Brant

  • Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan.

    Denise K. Bonen;Yasunori Ogura;Dan L. Nicolae;Naohiro Inohara

  • Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

    Mark S. Silverberg;Judy H. Cho;John D. Rioux;Dermot P B McGovern

  • Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1

    Judy H. Cho;Dan L. Nicolae;Leslee H. Gold;Carter T. Fields

  • A National Survey of the Prevalence and Impact of Clostridium difficile Infection Among Hospitalized Inflammatory Bowel Disease Patients

    Geoffrey C Nguyen;Gilaad G Kaplan;Mary L Harris;Steven R Brant

  • Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis

    Amir S. Karban;Toshihiko Okazaki;Carolien I.M. Panhuysen;Thomas Gallegos

  • Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3).

    C M Tse;S R Brant;M S Walker;J Pouyssegur

Frequent Co-Authors

Judy H. Cho
Judy H. Cho Icahn School of Medicine at Mount Sinai
John D. Rioux
John D. Rioux University of Montreal
Richard H. Duerr
Richard H. Duerr University of Pittsburgh
Mark S. Silverberg
Mark S. Silverberg University of Toronto
Dermot P.B. McGovern
Dermot P.B. McGovern Cedars-Sinai Medical Center
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Talin Haritunians
Talin Haritunians Cedars-Sinai Medical Center
Kent D. Taylor
Kent D. Taylor David Geffen School of Medicine at UCLA
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center

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