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Biology and Biochemistry

D-Index
56
Citations
9162
World Ranking
14638
National Ranking
1155

Overview

Rosalind E. Jenkins is affiliated with the University of Liverpool in the United Kingdom. Their research spans multiple topics within biochemistry, genetics, molecular biology, and medicine, reflecting a multidisciplinary approach to understanding biological processes and disease mechanisms.

Their recent publications demonstrate involvement in various areas such as drug-induced liver injury, cancer biology, immunology, and cellular homeostasis. Notable papers include:

  • The application of cytokeratin-18 as a biomarker for drug-induced liver injury (2021) published in Archives of Toxicology
  • Ras protein abundance correlates with Ras isoform mutation patterns in cancer (2023) published in Oncogene
  • Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation (2020) published in Toxicological Sciences
  • Glycation of Host Proteins Increases Pathogenic Potential of Porphyromonas gingivalis (2021) published in International Journal of Molecular Sciences
  • The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells (2021) published in Journal of Biological Chemistry

Frequent co-authors collaborating with Jenkins include Mandy J. Peffers, Emily J. Clarke, Victoria James, Stine Jacobsen, and Christopher E. Goldring. These collaborations suggest ongoing work in related research areas and a network of scientific partnerships.

Jenkins's work is regularly published in a variety of scientific venues, with frequent contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Archives of Toxicology
  • Toxicological Sciences
  • International Journal of Molecular Sciences
  • Scientific Reports

Their main fields of study are focused on Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad areas, Jenkins explores several subfields, including Molecular Biology, Pharmacology, Rheumatology, Epidemiology, and Immunology.

The primary research topics covered include:

  • Extracellular vesicles in disease
  • Osteoarthritis Treatment and Mechanisms
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Protein Kinase Regulation and GTPase Signaling
  • Genomics, phytochemicals, and oxidative stress
  • Pharmacogenetics and Drug Metabolism

Best Publications

  • Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

    Catherine C. Bell;Delilah F. G. Hendriks;Sabrina M. L. Moro;Ewa Ellis

  • Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics.

    Neil R. Kitteringham;Rosalind E. Jenkins;Catherine S. Lane;Victoria L. Elliott

  • The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

    Peter Huebener;Jean-Philippe Pradere;Celine Hernandez;Geum-Youn Gwak

  • Molecular forms of HMGB1 and keratin-18 as mechanistic biomarkers for mode of cell death and prognosis during clinical acetaminophen hepatotoxicity

    Daniel J. Antoine;Rosalind E. Jenkins;James W. Dear;Dominic P. Williams

  • Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

    Ian M. Copple;Adam Lister;Akua D. Obeng;Neil R. Kitteringham

  • Human leukocyte antigen (HLA)-B*57:01-restricted activation of drug-specific T cells provides the immunological basis for flucloxacillin-induced liver injury

    Manal M. Monshi;Lee Faulkner;Andrew Gibson;Rosalind E. Jenkins

  • High-Mobility Group Box-1 Protein and Keratin-18, Circulating Serum Proteins Informative of Acetaminophen-Induced Necrosis and Apoptosis In Vivo

    Daniel J. Antoine;Dominic P. Williams;Anja Kipar;Rosalind E. Jenkins

  • Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

    Neil R. Kitteringham;Azman Abdullah;Azman Abdullah;Joanne Walsh;Laura Randle

  • Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

    Benjamin L. Woolbright;Kenneth Dorko;Daniel J. Antoine;Joanna I. Clarke

  • The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.

    Ian M. Copple;Christopher E. Goldring;Rosalind E. Jenkins;Alvin J. L. Chia

  • Pancreatic cancer cells overexpress gelsolin family capping proteins which contribute to their cell motility

    Christopher C Thompson;Felicity J Ashcroft;Sabina Patel;Gabriella Saraga

  • Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo.

    Rosalind E. Jenkins;Xiaoli Meng;Victoria L. Elliott;Neil R. Kitteringham

  • A method for the rapid depletion of albumin and immunoglobulin from human plasma.

    Carrie Greenough;Rosalind E. Jenkins;Neil R. Kitteringham;Munir Pirmohamed

  • Arrays for protein expression profiling: towards a viable alternative to two-dimensional gel electrophoresis?

    Rosalind E. Jenkins;Stephen R. Pennington

  • Mass spectrometric characterization of circulating and functional antigens derived from piperacillin in patients with cystic fibrosis

    Paul Whitaker;Xiaoli Meng;Xiaoli Meng;Sidonie N. Lavergne;Sidonie N. Lavergne;Sabah El-Ghaiesh

  • Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation.

    Hayley E. Callan;Rosalind E. Jenkins;James L. Maggs;Sidonie N. Lavergne

  • Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis

    Rosalind E. Jenkins;Mark J. Taylor;Nichola J. Gilvary;Albert E. Bianco

  • S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility

    T Nedjadi;N Kitteringham;F Campbell;R E Jenkins

  • Abnormal carbohydrate composition of the major penetrating membrane protein of En(a-) human erythrocytes.

    M J Tanner;R E Jenkins;D J Anstee;J R Clamp

  • DNA sequence amplification in human prostate cancer identified by chromosome microdissection: potential prognostic implications

    C. Van Den Berg;Xin-Yuan Guan;D. Von Hoff;R. Jenkins

Frequent Co-Authors

B. Kevin Park
B. Kevin Park University of Liverpool
Dean J. Naisbitt
Dean J. Naisbitt University of Liverpool
Munir Pirmohamed
Munir Pirmohamed University of Liverpool
John P. Neoptolemos
John P. Neoptolemos Heidelberg University
James L. Maggs
James L. Maggs University of Liverpool
Neil French
Neil French University of Liverpool
Hartmut Jaeschke
Hartmut Jaeschke University of Kansas
Paul M. O'Neill
Paul M. O'Neill University of Liverpool
Murray E. Selkirk
Murray E. Selkirk Imperial College London
Mark J. Taylor
Mark J. Taylor Liverpool School of Tropical Medicine

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