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Rosa B. Barkardottir

Rosa B. Barkardottir

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
19818
World Ranking
11721
National Ranking
6

Overview

Rosa B. Barkardottir is affiliated with the University of Iceland in Iceland and has a research focus primarily situated within Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Genetics, Molecular Biology, Cancer Research, Reproductive Medicine, and Pathology and Forensic Medicine.

The research themes that Barkardottir explores cover a variety of topics such as BRCA gene mutations in cancer, Genetic Associations and Epidemiology, Ovarian cancer diagnosis and treatment, Cancer-related molecular mechanisms research, Bioinformatics and Genomic Networks, Nutrition, Genetics, and Disease, and DNA Repair Mechanisms.

Their publication record includes papers across multiple scientific venues. Frequent publication venues for Barkardottir's work include the European Journal of Human Genetics, Genes, bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, and Genetics in Medicine.

Recent papers authored or co-authored by Rosa B. Barkardottir include:

  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, 2020, Nature Genetics
  • Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants, 2020, Genetics in Medicine
  • Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants, 2020, JAMA Oncology
  • Polygenic risk modeling for prediction of epithelial ovarian cancer risk, 2022, European Journal of Human Genetics
  • Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways, 2021, PLoS ONE

Barkardottir has collaborated frequently with a group of co-authors, including Irene L. Andrulis, Daniel Barrowdale, Christoph Engel, D. Gareth Evans, and Maria A. Caligo, each with multiple joint publications.

Best Publications

  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

    D Ford;D F Easton;M Stratton;S Narod

  • Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

    Julius Gudmundsson;Patrick Sulem;Andrei Manolescu;Laufey T Amundadottir

  • A common variant associated with prostate cancer in European and African populations

    Laufey T. Amundadottir;Patrick Sulem;Julius Gudmundsson;Agnar Helgason

  • Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes

    Julius Gudmundsson;Patrick Sulem;Valgerdur Steinthorsdottir;Jon T. Bergthorsson

  • Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

    Sunil R. Lakhani;Jocelyne Jacquemier;John P Sloane;Barry A. Gusterson

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.

    Thorunn Rafnar;Patrick Sulem;Simon N Stacey;Frank Geller

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • Distinct Somatic Genetic Changes Associated with Tumor Progression in Carriers of BRCA1 and BRCA2 Germ-line Mutations

    Mika Tirkkonen;Oskar Johannsson;Bjarni A. Agnarsson;Håkan Olsson

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

    Julius Gudmundsson;Patrick Sulem;Thorunn Rafnar;Jon T. Bergthorsson

  • Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

    Julius Gudmundsson;Patrick Sulem;Daniel F Gudbjartsson;Thorarinn Blondal

  • Tumour biological features of BRCA1-induced breast and ovarian cancer.

    O T Jóhannsson;I Idvall;C Anderson;Åke Borg

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

    Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  • A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

    Simon N. Stacey;Patrick Sulem;Aslaug Jonasdottir;Gisli Masson

  • Evaluation of polygenic risk scores for breast and ovarian cancer risk prediction in BRCA1 and BRCA2 mutation carriers

    Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Lesley McGuffog;Daniel Barrowdale;Andrew Lee

  • High prevalence of the 999del5 mutation in Icelandic breast and ovarian cancer patients

    Gudrun Johannesdottir;Julius Gudmundsson;Jon T. Bergthorsson;Adalgeir Arason

  • The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.

    Sunil R. Lakhani;Barry A. Gusterson;Jocelyne Jacquemier;John P. Sloane

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

    Timothy R. Rebbeck;Tara M. Friebel;Eitan Friedman;Ute Hamann

Frequent Co-Authors

Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Åke Borg
Åke Borg Lund University
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Douglas F. Easton
Douglas F. Easton University of Cambridge
Ute Hamann
Ute Hamann German Cancer Research Center
Esther M. John
Esther M. John Stanford University
Melissa C. Southey
Melissa C. Southey Monash University
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Susan L. Neuhausen
Susan L. Neuhausen City Of Hope National Medical Center

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