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Chemistry

D-Index
63
Citations
19463
World Ranking
8282
National Ranking
2397

Overview

Romas J. Kazlauskas is affiliated with the University of Minnesota in the United States and has a focused research profile within the field of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple specialized subfields including Molecular Biology, Materials Chemistry, Genetics, Biotechnology, and Organic Chemistry.

Their main research topics include:

  • Enzyme Catalysis and Immobilization
  • Enzyme Structure and Function
  • Microbial Metabolic Engineering and Bioproduction
  • Bacterial Genetics and Biotechnology
  • Enzyme Production and Characterization
  • RNA and protein synthesis mechanisms
  • Protein Structure and Dynamics

The scientist has contributed to several peer-reviewed publications in notable venues. Their recent papers include:

  • From nature to industry: Harnessing enzymes for biocatalysis, 2023, Science
  • Consensus Finder web tool to predict stabilizing substitutions in proteins, 2020, Methods in enzymology on CD-ROM/Methods in enzymology
  • High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase, 2021, Applied and Environmental Microbiology
  • Plasmid hypermutation using a targeted artificial DNA replisome, 2021, Science Advances
  • Larger active site in an ancestral hydroxynitrile lyase increases catalytically promiscuous esterase activity, 2020, PLoS ONE

Romas J. Kazlauskas frequently collaborates with several other researchers. Among the most common co-authors are Robert L. Evans, Colin T. Pierce, Bryan J. Jones, Christine Luo, and Bo Guan, with several joint publications alongside each.

The main publication venues where their work appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • Science
  • Methods in enzymology on CD-ROM/Methods in enzymology
  • Applied and Environmental Microbiology

Best Publications

  • Engineering the third wave of biocatalysis

    Uwe T. Bornscheuer;G. W. Huisman;Romas J. Kazlauskas;Romas J. Kazlauskas;S. Lutz

  • Hydrolases in Organic Synthesis: Regio- and Stereoselective Biotransformations

    Uwe Theo Bornscheuer;Romas Joseph Kazlauskas

  • A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa

    Romas J. Kazlauskas;Romas J. Kazlauskas;Alexandra N. E. Weissfloch;Aviva T. Rappaport;Louis A. Cuccia

  • Biocatalysis in ionic liquids – advantages beyond green technology

    Seongsoon Park;Romas J Kazlauskas;Romas J Kazlauskas;Romas J Kazlauskas

  • Improved Preparation and Use of Room-Temperature Ionic Liquids in Lipase-Catalyzed Enantio- and Regioselective Acylations

    Seongsoon Park;Romas J. Kazlauskas

  • Catalytic Promiscuity in Biocatalysis: Using Old Enzymes to Form New Bonds and Follow New Pathways

    Uwe T. Bornscheuer;Romas J. Kazlauskas

  • Improving enzyme properties: when are closer mutations better?

    Krista L. Morley;Romas J. Kazlauskas

  • Hydrolase-catalyzed biotransformations in deep eutectic solvents.

    Johnathan T. Gorke;Friedrich Srienc;Romas J. Kazlauskas

  • A Structural Basis for the Chiral Preferences of Lipases

    Miroslaw Cygler;Pawel Grochulski;Romas J. Kazlauskas;Joseph D. Schrag

  • How the Same Core Catalytic Machinery Catalyzes 17 Different Reactions: the Serine-Histidine-Aspartate Catalytic Triad of α/β-Hydrolase Fold Enzymes

    Alissa Rauwerdink;Romas J. Kazlauskas

  • Toward advanced ionic liquids. Polar, enzyme-friendly solvents for biocatalysis

    Johnathan Gorke;Friedrich Srienc;Romas J Kazlauskas

  • Enhancing catalytic promiscuity for biocatalysis.

    Romas J Kazlauskas

  • Analogs of reaction intermediates identify a unique substrate binding site in Candida rugosa lipase.

    Pawel Grochulski;Francois Bouthillier;Romas J. Kazlauskas;Alessio N. Serreqi

  • Biotransformations with Lipases

    Romas J. Kazlauskas;Uwe T. Bornscheuer

  • Finding better protein engineering strategies.

    Romas J Kazlauskas;Uwe T Bornscheuer

  • QUANTITATIVE SCREENING OF HYDROLASE LIBRARIES USING PH INDICATORS: IDENTIFYING ACTIVE AND ENANTIOSELECTIVE HYDROLASES

    Lana E. Janes;A. Christina Löwendahl;Romas J. Kazlauskas

  • Enantiopreference of Lipase from Pseudomonas cepacia toward Primary Alcohols

    Alexandra N. E. Weissfloch;Romas J. Kazlauskas

  • A 2-Propanol Treatment Increases the Enantioselectivity of Candida rugosa Lipase toward Esters of Chiral Carboxylic Acids

    Ian J. Colton;Sharmin N. Ahmed;Romas J. Kazlauskas;Romas J. Kazlauskas

  • Manganese-Substituted Carbonic Anhydrase as a New Peroxidase

    Krzysztof Okrasa;Romas J. Kazlauskas

  • Resolution of Binaphthols and Spirobiindanols Using Cholesterol Esterase

    Romas J. Kazlauskas;Romas J. Kazlauskas

Frequent Co-Authors

Uwe T. Bornscheuer
Uwe T. Bornscheuer University of Greifswald
Friedrich Srienc
Friedrich Srienc University of Minnesota
Byung-Gee Kim
Byung-Gee Kim Seoul National University
Antony M. Dean
Antony M. Dean University of Minnesota
George M. Whitesides
George M. Whitesides Harvard University
Miroslaw Cygler
Miroslaw Cygler University of Saskatchewan
Karl Hult
Karl Hult Royal Institute of Technology
Jian-He Xu
Jian-He Xu East China University of Science and Technology
Robert H. Marchessault
Robert H. Marchessault McGill University

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