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Engineering and Technology

D-Index
32
Citations
4780
World Ranking
9547
National Ranking
2702

Overview

Pras Pathmanathan is affiliated with the US Food and Drug Administration in the United States. Their research work centers primarily on medicine, with a strong focus on cardiology and cardiovascular medicine. The subfields of study associated with their publications also include statistics and probability, electrical and electronic engineering, biomedical engineering, and artificial intelligence.

The topics covered in Pras Pathmanathan's work reflect a concentration on cardiac electrophysiology and arrhythmias, statistical methods in clinical trials, cardiovascular function and risk factors, and ECG monitoring and analysis. Additionally, their research involves machine learning applications in healthcare, gene regulatory network analysis, and computational drug discovery methods.

Their frequent co-authors include:

  • Richard A. Gray (6 co-publications)
  • Steven Niederer (5 co-publications)
  • Brent A. Craven (4 co-publications)
  • Tina Morrison (3 co-publications)
  • Tammo Delhaas (3 co-publications)

Pras Pathmanathan has published in a variety of scientific journals, with multiple contributions in:

  • PLoS Computational Biology (4 publications)
  • Frontiers in Physiology (3 publications)
  • Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences (2 publications)
  • Annals of Biomedical Engineering (2 publications)
  • European Heart Journal (1 publication)

Selected recent papers include:

  • The 'Digital Twin' to enable the vision of precision cardiology, 2020, European Heart Journal
  • Creation and application of virtual patient cohorts of heart models, 2020, Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • Chaste: Cancer, Heart and Soft Tissue Environment, 2020, The Journal of Open Source Software
  • Considering discrepancy when calibrating a mechanistic electrophysiology model, 2020, Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences
  • A Quantitative Systems Pharmacology Perspective on the Importance of Parameter Identifiability, 2022, Bulletin of Mathematical Biology

Best Publications

  • The 'Digital Twin' to enable the vision of precision cardiology.

    Jorge Corral-Acero;Francesca Margara;Maciej Marciniak;Cristobal Rodero

  • Chaste: an open source C++ library for computational physiology and biology.

    Gary R. Mirams;Christopher J. Arthurs;Miguel O. Bernabeu;Rafel Bordas

  • Verification of cardiac tissue electrophysiology simulators using an N-version benchmark

    Steven Alexander Niederer;Eric Kerfoot;Alan P. Benson;Miguel O. Bernabeu

  • Chaste: A test-driven approach to software development for biological modelling☆

    Joe Pitt-Francis;Pras Pathmanathan;Miguel O. Bernabeu;Rafel Bordas

  • An integrative computational model for intestinal tissue renewal

    I. M.M. Van Leeuwen;I. M.M. Van Leeuwen;G. R. Mirams;A. Walter;A. Fletcher

  • Advancing Regulatory Science With Computational Modeling for Medical Devices at the FDA's Office of Science and Engineering Laboratories

    Tina M. Morrison;Pras Pathmanathan;Mariam Adwan;Edward Margerrison

  • Uncertainty and variability in computational and mathematical models of cardiac physiology

    Gary R. Mirams;Pras Pathmanathan;Richard A. Gray;Peter Challenor

  • Patient-Specific Cardiovascular Computational Modeling: Diversity of Personalization and Challenges.

    Richard A. Gray;Pras Pathmanathan

  • Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?

    Ross H. Johnstone;Eugene T.Y. Chang;Rémi Bardenet;Teun P. de Boer

  • A hybrid approach to multi-scale modelling of cancer

    J. M. Osborne;A. Walter;S. K. Kershaw;G. R. Mirams

  • A computational study of discrete mechanical tissue models.

    P Pathmanathan;J Cooper;A Fletcher;G Mirams

  • Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials

    Nejib Zemzemi;Nejib Zemzemi;Miguel O Bernabeu;Javier Saiz;Jonathan Cooper

  • Predicting Tumor Location by Modeling the Deformation of the Breast

    P. Pathmanathan;D.J. Gavaghan;J.P. Whiteley;S.J. Chapman

  • Chaste: using agile programming techniques to develop computational biology software

    Joe Pitt-Francis;Miguel O Bernabeu;Jonathan Cooper;Alan Garny

  • A numerical guide to the solution of the bidomain equations of cardiac electrophysiology

    Pras Pathmanathan;Miguel O. Bernabeu;Rafel Bordas;Jonathan Cooper

  • Creation and application of virtual patient cohorts of heart models

    S. A. Niederer;Y. Aboelkassem;C. D. Cantwell;C. Corrado

  • Chaste: Cancer, Heart and Soft Tissue Environment

    Fergus R. Cooper;Ruth E. Baker;Miguel O. Bernabeu;Rafel Bordas

  • Comprehensive Uncertainty Quantification and Sensitivity Analysis for Cardiac Action Potential Models.

    Pras Pathmanathan;Jonathan M. Cordeiro;Richard A. Gray

  • Predicting Tumour Location by Simulating Large Deformations of the Breast Using a 3D Finite Element Model and Nonlinear Elasticity

    Pras Pathmanathan;David Gavaghan;Jonathan Whiteley;Sir Michael Brady

  • A numerical method for cardiac mechanoelectric simulations.

    Pras Pathmanathan;Jonathan P. Whiteley

  • CARDIAC ELECTROMECHANICS: THE EFFECT OF CONTRACTION MODEL ON THE MATHEMATICAL PROBLEM AND ACCURACY OF THE NUMERICAL SCHEME

    P. Pathmanathan;S. J. Chapman;D. J. Gavaghan;J. P. Whiteley

  • Verification of computational models of cardiac electro-physiology

    Pras Pathmanathan;Richard A. Gray

  • Uncertainty quantification of fast sodium current steady-state inactivation for multi-scale models of cardiac electrophysiology.

    Pras Pathmanathan;Matthew S. Shotwell;David J. Gavaghan;Jonathan M. Cordeiro

  • Applicability Analysis of Validation Evidence for Biomedical Computational Models

    Pras Pathmanathan;Richard A. Gray;Vicente J. Romero;Tina M. Morrison

  • The significant effect of the choice of ionic current integration method in cardiac electro‐physiological simulations

    Pras Pathmanathan;Gary R. Mirams;James Southern;Jonathan P. Whiteley

  • Ensuring reliability of safety-critical clinical applications of computational cardiac models.

    Pras Pathmanathan;Richard A. Gray

Frequent Co-Authors

Helen M. Byrne
Helen M. Byrne University of Oxford
Philip K. Maini
Philip K. Maini University of Oxford
Oliver E. Jensen
Oliver E. Jensen University of Manchester
Keith Worden
Keith Worden University of Sheffield
Kevin Burrage
Kevin Burrage Queensland University of Technology
Poul M. F. Nielsen
Poul M. F. Nielsen University of Auckland
Bradley J. Roth
Bradley J. Roth Oakland University
Gernot Plank
Gernot Plank Medical University of Graz
Martyn P. Nash
Martyn P. Nash University of Auckland
Peter D. Lee
Peter D. Lee University College London

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