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Biology and Biochemistry

D-Index
62
Citations
11881
World Ranking
10948
National Ranking
119

Overview

Pablo I. Nikel is affiliated with the Technical University of Denmark in Denmark. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a substantial body of work spanning 242 publications in this area. Their studies extensively cover several subfields, including Molecular Biology, Genetics, Ecology, Biomedical Engineering, and Environmental Engineering.

The main topics addressed in Nikel's research include:

  • Microbial Metabolic Engineering and Bioproduction
  • Bacterial Genetics and Biotechnology
  • Enzyme Catalysis and Immobilization
  • CRISPR and Genetic Engineering
  • Microbial Community Ecology and Physiology
  • Biofuel production and bioconversion
  • Microbial Fuel Cells and Bioremediation

Nikel has contributed multiple research articles published in frequent venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbial Biotechnology
  • Nature Communications
  • Metabolic Engineering
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

Among the recent papers associated with Nikel's work are:

  • "Industrial biotechnology of Pseudomonas putida: advances and prospects" (2020, Applied Microbiology and Biotechnology)
  • "Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress" (2021, The ISME Journal)
  • "Engineering Native and Synthetic Pathways in Pseudomonas putida for the Production of Tailored Polyhydroxyalkanoates" (2020, Biotechnology Journal)
  • "Synthetic control of plasmid replication enables target- and self-curing of vectors and expedites genome engineering of Pseudomonas putida" (2020, Metabolic Engineering Communications)
  • "Growth-coupled selection of synthetic modules to accelerate cell factory development" (2021, Nature Communications)

Frequent collaborators in Nikel's research include:

  • Daniel C. Volke
  • Nicolas T. Wirth
  • Manuel Nieto-Domínguez
  • Víctor de Lorenzo
  • Enrico Orsi

Best Publications

  • The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes

    Rafael Silva-Rocha;Esteban Martínez-García;Belen Calles;Max Chavarría

  • Pseudomonas putida as a functional chassis for industrial biocatalysis: From native biochemistry to trans-metabolism.

    Pablo I. Nikel;Víctor de Lorenzo

  • Biotechnological domestication of pseudomonads using synthetic biology

    Pablo I. Nikel;Esteban Martínez-García;Víctor de Lorenzo

  • Pseudomonas putida KT2440 Strain Metabolizes Glucose through a Cycle Formed by Enzymes of the Entner-Doudoroff, Embden-Meyerhof-Parnas, and Pentose Phosphate Pathways *

    Pablo Ivan Nikel;Max Chavarria;Tobias Fuhrer;Uwe Sauer

  • The revisited genome of Pseudomonas putida KT2440 enlightens its value as a robust metabolic chassis.

    Eugeni Belda;Eugeni Belda;Ruben G. A. van Heck;Maria Jose Lopez-Sanchez;Stephane Cruveiller

  • Bioremediation 3.0: Engineering pollutant-removing bacteria in the times of systemic biology.

    Pavel Dvořák;Pablo Ivan Nikel;Jiří Damborský;Victor de Lorenzo

  • Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non-traditional microorganisms.

    Patricia Calero;Pablo I. Nikel

  • Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway

    Pavel Dvorak;Lukas Chrast;Pablo I. Nikel;Radek Fedr

  • Pseudomonas 2.0: genetic upgrading of P. putida KT2440 as an enhanced host for heterologous gene expression

    Esteban Martínez-García;Pablo Ivan Nikel;Tomás Aparicio;Victor de Lorenzo

  • The Entner–Doudoroff pathway empowers Pseudomonas putida KT2440 with a high tolerance to oxidative stress

    Max Chavarría;Max Chavarría;Pablo I. Nikel;Danilo Pérez-Pantoja;Víctor de Lorenzo

  • From dirt to industrial applications: Pseudomonas putida as a Synthetic Biology chassis for hosting harsh biochemical reactions.

    Pablo Ivan Nikel;Max Chavarría;Antoine Danchin;Victor de Victor de Lorenzo

  • Industrial biotechnology of Pseudomonas putida: advances and prospects

    Anna Weimer;Michael Kohlstedt;Daniel C Volke;Pablo I Nikel

  • Genome reduction boosts heterologous gene expression in Pseudomonas putida.

    Sarah Lieder;Pablo Ivan Nikel;Victor de Lorenzo;Ralf Takors

  • The metabolic cost of flagellar motion in Pseudomonas putida KT2440.

    Esteban Martínez-García;Pablo Ivan Nikel;Max Chavarría;Victor de Lorenzo

  • New recombinant Escherichia coli strain tailored for the production of poly(3-hydroxybutyrate) from agroindustrial by-products.

    Pablo I. Nikel;Pablo I. Nikel;Alejandra de Almeida;Evelia C. Melillo;Miguel A. Galvagno;Miguel A. Galvagno

  • New transposon tools tailored for metabolic engineering of gram-negative microbial cell factories.

    Esteban Martínez-García;Tomás Aparicio;Víctor de Lorenzo;Pablo I. Nikel

  • Revolutionizing agriculture with synthetic biology.

    Eleanore T. Wurtzel;Claudia E. Vickers;Claudia E. Vickers;Andrew D. Hanson;A. Harvey Millar

  • Poly(3-hydroxybutyrate) synthesis from glycerol by a recombinant Escherichia coli arcA mutant in fed-batch microaerobic cultures

    Pablo I. Nikel;Pablo I. Nikel;M. Julia Pettinari;Miguel A. Galvagno;Miguel A. Galvagno;Beatriz S. Méndez

  • Accelerated genome engineering of Pseudomonas putida by I-SceI―mediated recombination and CRISPR-Cas9 counterselection

    Nicolas Wirth;Ekaterina Kozaeva;Pablo Ivan Nikel

  • Engineering an anaerobic metabolic regime in Pseudomonas putida KT2440 for the anoxic biodegradation of 1,3-dichloroprop-1-ene

    Pablo I. Nikel;Víctor de Lorenzo

Frequent Co-Authors

Víctor de Lorenzo
Víctor de Lorenzo Spanish National Research Council
Antoine Danchin
Antoine Danchin Institut Cochin
Christoph Wittmann
Christoph Wittmann Saarland University
Ka-Yiu San
Ka-Yiu San Rice University
Uwe Sauer
Uwe Sauer ETH Zurich
Diethard Mattanovich
Diethard Mattanovich BOKU University
George N. Bennett
George N. Bennett Rice University
Helle Krogh Johansen
Helle Krogh Johansen University of Copenhagen
Hans-Peter Klenk
Hans-Peter Klenk Newcastle University
Claire M. Fraser
Claire M. Fraser University of Maryland, Baltimore

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