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76
Citations
58683
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4908
National Ranking
367

Overview

Miles Parkes is affiliated with the University of Cambridge in the United Kingdom. Their research predominantly focuses on Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in the subfields of Genetics, Epidemiology, Surgery, Immunology, and Infectious Diseases.

The scientist's main areas of study include inflammatory bowel disease (IBD), microscopic colitis, gut microbiota and health, gastrointestinal motility and disorders, Helicobacter pylori-related gastroenterology studies, SARS-CoV-2 and COVID-19 research, and immunodeficiency and autoimmune disorders.

Parkes has authored several papers, notable examples include:

  • British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic, 2020, Gut
  • A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn's disease (PROFILE): a multicentre, open-label randomised controlled trial, 2024, The Lancet. Gastroenterology & Hepatology
  • Somatic Evolution in Non-neoplastic IBD-Affected Colon, 2020, Cell
  • Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries, 2023, Nature Genetics
  • COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study, 2022, The Lancet. Gastroenterology & Hepatology

Frequent co-authors in Parkes's publications include:

  • Tim Raine
  • Nicholas A. Kennedy
  • Peter M. Irving
  • Ailsa Hart
  • Tariq Ahmad

Parkes's work appears commonly in the following publication venues:

  • Journal of Crohn's and Colitis
  • The Lancet. Gastroenterology & Hepatology
  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gut

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr

  • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

    Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho

  • Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

    Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang

  • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

    Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal

  • Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

    J Z Liu;S van Sommeren;H Huang;S C Ng

  • British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

    Christopher Andrew Lamb;Christopher Andrew Lamb;Nicholas A Kennedy;Tim Raine;Philip Anthony Hendy;Philip Anthony Hendy

  • Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

    Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke

  • Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

    Katrina M de Lange;Loukas Moutsianas;James C Lee;Christopher A Lamb

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

    Miles Parkes;Jeffrey C Barrett;Natalie J Prescott;Mark Tremelling

  • Disease-specific alterations in the enteric virome in inflammatory bowel disease.

    Jason M. Norman;Scott A. Handley;Megan T. Baldridge;Lindsay Droit

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12.

    J Satsangi;M Parkes;E Louis;L Hashimoto

  • Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

    David Ellinghaus;Luke Jostins;Sarah L. Spain;Adrian Cortes

  • Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

    Isabelle Cleynen;Isabelle Cleynen;Gabrielle Boucher;Luke Jostins;Luke Jostins;Luke Jostins;L Philip Schumm

  • New IBD genetics: common pathways with other diseases

    C W Lees;J C Barrett;M Parkes;J Satsangi

  • Meta-analysis and imputation refines the association of 15q25 with smoking quantity

    Jason Z. Liu;Federica Tozzi;Dawn M. Waterworth;Sreekumar G. Pillai

  • Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

    Sergey Nejentsev;Joanna M. M. Howson;Neil M. Walker;Jeffrey Szeszko

Frequent Co-Authors

Jack Satsangi
Jack Satsangi University of Oxford
Tariq Ahmad
Tariq Ahmad Yale University
James Lee
James Lee The Francis Crick Institute
Derek P. Jewell
Derek P. Jewell University of Oxford
Carl A. Anderson
Carl A. Anderson Wellcome Sanger Institute
Christopher G. Mathew
Christopher G. Mathew King's College London
Jeremy D. Sanderson
Jeremy D. Sanderson Guy's and St Thomas' NHS Foundation Trust
Natalie J. Prescott
Natalie J. Prescott King's College London
Willem H. Ouwehand
Willem H. Ouwehand University of Cambridge
Matthew A. Brown
Matthew A. Brown Guy's and St Thomas' NHS Foundation Trust

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