Miles Parkes mainly focuses on Genetics, Genome-wide association study, Genetic association, Inflammatory bowel disease and Disease. His biological study deals with issues like Allele, which deal with fields such as Genotyping, Missense mutation and Human leukocyte antigen. Miles Parkes focuses mostly in the field of Genetic association, narrowing it down to topics relating to Candidate gene and, in certain cases, Colorectal cancer and Expression quantitative trait loci.
His Inflammatory bowel disease research is multidisciplinary, incorporating elements of Genome, Immunology and Ulcerative colitis. His study looks at the intersection of Disease and topics like Genotype with Genetic heterogeneity, Chromosome 3 and Gene mapping. The study incorporates disciplines such as Population stratification, Human genetics and CDKN2BAS in addition to Allele frequency.
His primary areas of study are Inflammatory bowel disease, Genetics, Immunology, Disease and Ulcerative colitis. His Inflammatory bowel disease research incorporates elements of Crohn's disease, Cancer research, Genetic predisposition and Candidate gene. His study in Genome-wide association study, Genetic association, Single-nucleotide polymorphism, Locus and Allele are all subfields of Genetics.
He interconnects Case-control study, ATG16L1 and Genotype in the investigation of issues within Immunology. His Disease study combines topics from a wide range of disciplines, such as Immunosuppression and Genome. His work deals with themes such as Surgery and Colitis, which intersect with Ulcerative colitis.
His scientific interests lie mostly in Inflammatory bowel disease, Internal medicine, Crohn's disease, Ulcerative colitis and Disease. His Inflammatory bowel disease study combines topics in areas such as Cancer research, Irritable bowel syndrome, Immunology, Vaccination and Gene. The Immunology study combines topics in areas such as Allele and Age of onset.
His work focuses on many connections between Internal medicine and other disciplines, such as Gastroenterology, that overlap with his field of interest in Azathioprine. His studies deal with areas such as Colonoscopy, Primary sclerosing cholangitis and Diagnostic odds ratio, Confidence interval as well as Ulcerative colitis. The various areas that Miles Parkes examines in his Disease study include Transcriptome, Response to treatment, Computational biology, Cohort and Candidate gene.
Inflammatory bowel disease, Ulcerative colitis, Internal medicine, Crohn's disease and Gastroenterology are his primary areas of study. In his study, which falls under the umbrella issue of Inflammatory bowel disease, Enteropathy, Allele and Age of onset is strongly linked to Immunology. His studies in Ulcerative colitis integrate themes in fields like Antibody receptor, Immune system, Immunity and Mutation rate.
His study on Clinical trial, Infliximab, Pouchitis and Disease management is often connected to Government as part of broader study in Internal medicine. His Crohn's disease research is within the category of Disease. His Disease study integrates concerns from other disciplines, such as Intensive care medicine, Response to treatment and Quality of life.
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock.
Nature (2007)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr.
Nature (2012)
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho.
Nature Genetics (2008)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang.
Nature Genetics (2010)
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Daniel J. Klionsky;Hagai Abeliovich;Patrizia Agostinis;Devendra K. Agrawal.
Autophagy (2008)
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.
Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke.
Nature Genetics (2011)
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
Miles Parkes;Jeffrey C Barrett;Natalie J Prescott;Mark Tremelling.
Nature Genetics (2007)
Genome-wide association study identifies eight loci associated with blood pressure
Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin.
Nature Genetics (2009)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock.
Nature Genetics (2007)
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
J Z Liu;S van Sommeren;H Huang;S C Ng.
Nature Genetics (2015)
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