D-Index & Metrics Best Publications
Genetics
UK
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 104 Citations 62,751 337 World Ranking 4083 National Ranking 401
Genetics D-index 102 Citations 62,342 304 World Ranking 423 National Ranking 66

Research.com Recognitions

Awards & Achievements

2023 - Research.com Genetics in United Kingdom Leader Award

Fellow of The Academy of Medical Sciences, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Mutation
  • Genetics

Christopher G. Mathew spends much of his time researching Genetics, Genome-wide association study, Genetic association, Single-nucleotide polymorphism and Inflammatory bowel disease. His Genetics study focuses mostly on Fanconi anemia, Fanconi anemia, complementation group C, Allele, Candidate gene and IRGM. His Genome-wide association study research includes elements of Bioinformatics, Copy-number variation, Disease, Locus and Genetic architecture.

His Genetic association study incorporates themes from Psoriasis, Genetic predisposition, Methylenetetrahydrofolate reductase, Blood pressure and Expression quantitative trait loci. His Single-nucleotide polymorphism research incorporates themes from Hemodynamics, ATG16L1 and Allele frequency. Christopher G. Mathew has researched Inflammatory bowel disease in several fields, including Common disease-common variant, Nonsynonymous substitution, NOD2, Ulcerative colitis and Genetic linkage.

His most cited work include:

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls (7922 citations)
  • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease (3117 citations)
  • Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease (2233 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Genetics, Immunology, Inflammatory bowel disease, Genome-wide association study and Gene. His study in Locus, Genetic association, Single-nucleotide polymorphism, Fanconi anemia and Allele is carried out as part of his studies in Genetics. His studies deal with areas such as Psoriasis and Candidate gene as well as Genetic association.

His study focuses on the intersection of Immunology and fields such as Crohn's disease with connections in the field of Gastroenterology. His Inflammatory bowel disease research is multidisciplinary, relying on both Genetic linkage and Ulcerative colitis. His Genome-wide association study research integrates issues from Odds ratio, Genetic predisposition, Case-control study, Allele frequency and Genetic architecture.

He most often published in these fields:

  • Genetics (63.64%)
  • Immunology (22.73%)
  • Inflammatory bowel disease (23.30%)

What were the highlights of his more recent work (between 2012-2021)?

  • Genetics (63.64%)
  • Genome-wide association study (24.72%)
  • Inflammatory bowel disease (23.30%)

In recent papers he was focusing on the following fields of study:

Christopher G. Mathew mostly deals with Genetics, Genome-wide association study, Inflammatory bowel disease, Internal medicine and Genetic association. Gene, Single-nucleotide polymorphism, Allele, Locus and Phenotype are among the areas of Genetics where Christopher G. Mathew concentrates his study. His research investigates the connection with Single-nucleotide polymorphism and areas like Genetic predisposition which intersect with concerns in University hospital and Tissue damage.

His Genome-wide association study research includes themes of Odds ratio, Psychosis, Allele frequency, Disease and Genetic architecture. His Inflammatory bowel disease study combines topics in areas such as Lamina propria, Cancer research and Ulcerative colitis. His biological study spans a wide range of topics, including Exome sequencing, Exome, Missense mutation, Genotyping and Missing heritability problem.

Between 2012 and 2021, his most popular works were:

  • Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease (421 citations)
  • Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease (421 citations)
  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (328 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Mutation
  • Genetics

Christopher G. Mathew mainly focuses on Genetics, Genome-wide association study, Inflammatory bowel disease, Genetic association and Allele. His DNA replication, Chromosome instability and Gene duplication study, which is part of a larger body of work in Genetics, is frequently linked to DNA-binding protein and Replisome, bridging the gap between disciplines. The subject of his Genome-wide association study research is within the realm of Single-nucleotide polymorphism.

The various areas that he examines in his Inflammatory bowel disease study include Cancer research, Genotype and Ulcerative colitis. His research in Genetic association focuses on subjects like Missense mutation, which are connected to Exome. His work carried out in the field of Allele brings together such families of science as Immune system and ITGB8.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock.
Nature (2007)

8473 Citations

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Luke Jostins;Stephan Ripke;Rinse K Weersma;Richard H Duerr.
Nature (2012)

4404 Citations

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Jeffrey C. Barrett;Sarah Hansoul;Dan L. Nicolae;Judy H. Cho.
Nature Genetics (2008)

3041 Citations

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Andre Franke;Dermot P B McGovern;Jeffrey C. Barrett;Kai Wang.
Nature Genetics (2010)

2861 Citations

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer.
Nature (2011)

2667 Citations

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

Jochen Hampe;Andre Franke;Philip Rosenstiel;Philip Rosenstiel;Andreas Till.
Nature Genetics (2007)

2119 Citations

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Carl A. Anderson;Gabrielle Boucher;Charlie W. Lees;Andre Franke.
Nature Genetics (2011)

1509 Citations

Genome-wide association study identifies eight loci associated with blood pressure

Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin.
Nature Genetics (2009)

1383 Citations

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.

Miles Parkes;Jeffrey C Barrett;Natalie J Prescott;Mark Tremelling.
Nature Genetics (2007)

1370 Citations

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

Jochen Hampe;Andrew Cuthbert;Peter J. P. Croucher;Muddassar M. Mirza.
The Lancet (2001)

1349 Citations

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