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Biology and Biochemistry

D-Index
53
Citations
6714
World Ranking
16394
National Ranking
6776

Overview

Michael G. O'Rand is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans several areas within biochemistry, genetics, molecular biology, and medicine, with notable contributions particularly in reproductive biology and molecular mechanisms related to sperm and testicular function.

Their frequent publication venues include UNC Libraries, where the majority of their work has appeared, as well as Scientific Reports and Drug Delivery and Translational Research. This distribution reflects a focus on both institutional archival publications and peer-reviewed scientific journals.

O'Rand's main fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad fields, their subfields of study include:

  • Molecular Biology
  • Reproductive Medicine
  • Public Health, Environmental and Occupational Health
  • Insect Science
  • Immunology

The primary topics addressed in their papers are:

  • Sperm and Testicular Function
  • Heat shock proteins research
  • RNA Interference and Gene Delivery
  • RNA Research and Splicing
  • Reproductive Biology and Fertility
  • Insect and Pesticide Research
  • Bee Products Chemical Analysis

Their notable recent papers include:

  • Interactions of the male contraceptive target EPPIN with semenogelin-1 and small organic ligands (2023, Scientific Reports)
  • Site-directed Mutagenesis of Rabbit Proacrosin: Identification of Residues Involved in Zona Pellucida Binding (2021, UNC Libraries)
  • Association of NASP with HSP90 in Mouse Spermatogenic Cells: Stimulation of ATPase Activity and Transport of Linker Histones into Nuclei (2021, UNC Libraries)
  • Processing of the Sperm Protein Sp17 during the Acrosome Reaction and Characterization as a Calmodulin Binding Protein (2021, UNC Libraries)
  • Linker Histones Stimulate HSPA2 ATPase Activity Through NASP Binding and Inhibit CDC2/Cyclin B1 Complex Formation During Meiosis in the Mouse (2020, UNC Libraries)

O'Rand frequently collaborates with several researchers, among whom are:

  • Richard T. Richardson
  • Katherine G. Hamil
  • Esther E. Widgren
  • Erick J. R. Silva
  • Oleg Alekseev

Best Publications

  • Reversible immunocontraception in male monkeys immunized with eppin.

    M. G. O'Rand;E. E. Widgren;P. Sivashanmugam;R. T. Richardson

  • Characterization of the rabbit sperm membrane autoantigen, RSA, as a lectin-like zona binding protein.

    Michael G. O'Rand;Esther E. Widgren;Susan J. Fisher

  • Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis.

    Richard T Richardson;Perumal Sivashanmugam;Susan H Hall;Katherine G Hamil

  • Sequence of a rabbit sperm zona pellucida binding protein and localization during the acrosome reaction.

    Richard T. Richardson;Noriyuki Yamasaki;Michael G. O'Rand

  • Characterization of the Histone H1-binding Protein, NASP, as a Cell Cycle-regulated Somatic Protein

    Richard T. Richardson;Iglika N. Batova;Esther E. Widgren;Lian Xing Zheng

  • Sperm-egg recognition and barriers to interspecies fertilization.

    Michael G. O'Rand

  • Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation.

    Richard T. Richardson;Oleg M. Alekseev;Gail Grossman;Esther E. Widgren

  • Antimicrobial Activity of Human EPPIN, an Androgen-Regulated, Sperm-Bound Protein with a Whey Acidic Protein Motif

    Suresh Yenugu;Richard T. Richardson;Perumal Sivashanmugam;Zengjun Wang

  • HE2beta and HE2gamma, new members of an epididymis-specific family of androgen-regulated proteins in the human.

    Katherine G. Hamil;P. Sivashanmugam;Richard T. Richardson;Gail Grossman

  • Identification and distribution of actin in spermatogenic cells and spermatozoa of the rabbit

    Jeffrey E. Welch;Michael G. O'Rand

  • Association of Eppin with Semenogelin on Human Spermatozoa

    Zengjun Wang;E.E. Widgren;P. Sivashanmugam;M.G. O'Rand

  • Inhibition of Fertility and Sperm-Zona Binding by Antiserum to the Rabbit Sperm Membrane Autoantigen RSA-1

    Michael G. O’rand

  • Identification of zona binding proteins of rabbit, pig, human, and mouse spermatozoa on nitrocellulose blots

    Michael G. O'Rand;Jessica E. Matthews;Jeffrey E. Welch;Susan J. Fisher

  • Sequence and localization of the mouse sperm autoantigenic protein, Sp17.

    Min Kong;Richard T. Richardson;Esther E. Widgren;Michael G. O’Rand

  • Localization of zona pellucida binding sites on rabbit spermatozoa and induction of the acrosome reaction by solubilized zonae

    Michael G. O'Rand;Susan J. Fisher

  • Monoclonal antibodies to rabbit sperm autoantigens. I. Inhibition of in vitro fertilization and localization on the egg.

    Michael G. O’Rand;Grace P. Irons;James P. Porter

  • Semen parameters and fertilization of human oocytes in vitro: a multivariable analysis

    Luther M. Talbert;Mary G. Hammond;Jouko Halme;Michael O’Rand

  • Characterization of an Eppin Protein Complex from Human Semen and Spermatozoa

    Zengjun Wang;Esther E. Widgren;Richard T. Richardson;Michael G. O'Rand

  • Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17.

    I.A. Lea;R.T. Richardson;E.E. Widgren;M.G. O'Rand

  • Characterization of Sp17: a ubiquitous three domain protein that binds heparin

    Ying Wen;Richard T. Richardson;Esther E. Widgren;Michael G. O'rand

Frequent Co-Authors

Frank S. French
Frank S. French University of North Carolina at Chapel Hill
Christopher D. Pilcher
Christopher D. Pilcher University of California, San Francisco
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Jan Münch
Jan Münch University of Ulm
William F. Marzluff
William F. Marzluff University of North Carolina at Chapel Hill
Warner C. Greene
Warner C. Greene University of California, San Francisco
Steven M. Ruben
Steven M. Ruben Celera Corporation
Brian Herman
Brian Herman The University of Texas Health Science Center at San Antonio
Paul A. Moore
Paul A. Moore MacroGenics (United States)
Michael A. Tainsky
Michael A. Tainsky Wayne State University

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