Michael D. Been

Overview

Best Publications

• Rna ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods.

  Thomas R. Cech;Arthur J. Zaug;Michael D. Been

  1074
  Citations

• A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA.

  Anne T. Perrotta;Michael D. Been

  484
  Citations

• The Tetrahymena ribozyme acts like an RNA restriction endonuclease

  Arthur J. Zaug;Michael D. Been;Thomas R. Cech

  451
  Citations

• Imidazole Rescue of a Cytosine Mutation in a Self-Cleaving Ribozyme

  Anne T. Perrotta;I-hung Shih;Michael D. Been

  374
  Citations

• One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity.

  Michael D. Been;Thomas R. Cech

  309
  Citations

• Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis delta virus RNA sequence.

  Anne T. Perrotta;Michael D. Been

  288
  Citations

• Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA

  Michael D. Been;Richard R. Burgess;James J. Champoux

  272
  Citations

• Exon circularization in mammalian nuclear extracts.

  Zvi Pasman;Michael D. Been;Mariano Garcia-Blanco

  235
  Citations

• Self-cleaving ribozymes of hepatitis delta virus RNA.

  Michael D. Been;Gene S. Wickham

  217
  Citations

• Group I permuted intron-exon (PIE) sequences self-splice to produce circular exons.

  M. Puttaraju;Michael Been

  186
  Citations

• Numerous group I introns with variable distributions in the ribosomal DNA of a lichen fungus

  Paula T. DePriest;Michael D. Been

  176
  Citations

• The self-cleaving domain from the genomic RNA of hepatitis delta virus: sequence requirements and the effects of denaturant

  Anne T. Perrotta;Michael D. Been

  174
  Citations

• Catalytic Strategies of the Hepatitis Delta Virus Ribozymes

  I-hung Shih;Michael D Been

  157
  Citations

• RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme

  Michael D. Been;Thomas R. Cech

  155
  Citations

• Secondary structure of the self-cleaving RNA of hepatitis delta virus: applications to catalytic RNA design.

  Michael D. Been;Anne T. Perrotta;Sarah P. Rosenstein

  135
  Citations

• Group I intron self-splicing with adenosine: evidence for a single nucleoside-binding site.

  Michael D. Been;Anne T. Perrotta

  132
  Citations

• Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage

  I-hung Shih;Michael D. Been

  118
  Citations

• A circular trans-acting hepatitis delta virus ribozyme

  M. Puttaraju;Anne T. Perrotta;Michael D. Been

  117
  Citations

• A nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes.

  Timothy S. Wadkins;Anne T. Perrotta;Adrian R. Ferré-D'amaré;Jennifer A. Doudna

  115
  Citations

• A pH-sensitive RNA tertiary interaction affects self-cleavage activity of the HDV ribozymes in the absence of added divalent metal ion

  Timothy S Wadkins;I-hung Shih;Anne T Perrotta;Michael D Been

  113
  Citations