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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
11060
World Ranking
14451
National Ranking
6079

Research.com Recognitions

  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2004 - Fellow of American Physical Society (APS) Citation For his creative, stimulating, and seminal contributions to various subjects in Fluid Dynamics, namely to fluid singularities, single bubble sonoluminescence, electrohydrodynamics, and sedimentation
  • 2004 - Fellow of John Simon Guggenheim Memorial Foundation
  • 1997 - Fellow of Alfred P. Sloan Foundation

Overview

Michael Brenner is affiliated with the University of Alabama at Birmingham in the United States. Their research spans several interrelated fields including Biochemistry, Genetics and Molecular Biology, Medicine, and Neuroscience.

Brenner's scholarly output includes work in notable subfields such as Molecular Biology, Oncology, Neurology, Cellular and Molecular Neuroscience, and Immunology. Their research emphasizes topics like RNA Research and Splicing, RNA regulation and disease, CAR-T cell therapy research, RNA Interference and Gene Delivery, Neurological diseases and metabolism, Nerve injury and regeneration, as well as Hereditary Neurological Disorders.

Recent papers authored or co-authored by Michael Brenner include:

  • Regulation of GFAP Expression, 2021, ASN NEURO
  • GFAP at 50, 2020, ASN NEURO
  • ImmGen at 15, 2020, Nature Immunology
  • Type II Alexander disease caused by splicing errors and aberrant overexpression of an uncharacterized GFAP isoform, 2020, Human Mutation
  • Endothelial cell sphingosine 1-phosphate receptor 1 restrains VE-cadherin cleavage and attenuates experimental inflammatory arthritis, 2024, JCI Insight

Frequent co-authors of Brenner are:

  • Albee Messing
  • Vladimir Jojic
  • Susan M. Goodman
  • R. Wang
  • Anvita Singaraju

Most publications have appeared in the following venues:

  • ASN NEURO
  • Annals of the Rheumatic Diseases
  • Nature Immunology
  • Human Mutation
  • JCI Insight

Michael Brenner has received several professional recognitions, including:

  • Fellow of the American Academy of Arts and Sciences, 2014
  • Fellow of John Simon Guggenheim Memorial Foundation, 2004
  • Fellow of American Physical Society (APS), 2004 - Citation for creative, stimulating, and seminal contributions to fluid dynamics, including fluid singularities, single bubble sonoluminescence, electrohydrodynamics, and sedimentation
  • Fellow of Alfred P. Sloan Foundation, 1997

Best Publications

  • Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease.

    Michael Brenner;Anne B. Johnson;Odile Boespflug-Tanguy;Diana Rodriguez

  • hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo.

    Lang Zhuo;Martin Theis;Ikuri Alvarez-Maya;Michael Brenner

  • GFAP promoter directs astrocyte-specific expression in transgenic mice

    M. Brenner;W. C. Kisseberth;Yuan Su;F. Besnard

  • Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology

    M A McCall;R G Gregg;R R Behringer;M Brenner

  • GFAP promoter elements required for region‐specific and astrocyte‐specific expression

    Youngjin Lee;Albee Messing;Mu Su;Michael Brenner

  • Suppression of protein synthesis in brain during hibernation involves inhibition of protein initiation and elongation.

    Kai U. Frerichs;Carolyn B. Smith;Michael Brenner;Donald J. DeGracia

  • Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice

    A Messing;Mark Head;K Galles;EJ Galbreath

  • Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease.

    Rong Li;Anne B. Johnson;Gajja Salomons;James E. Goldman

  • GFAP mutations, age at onset, and clinical subtypes in Alexander disease

    M. Prust;J. Wang;H. Morizono;A. Messing

  • GFAP and its role in Alexander disease.

    Roy A. Quinlan;Michael Brenner;James E. Goldman;Albee Messing

  • Role of GFAP in CNS injuries.

    Michael Brenner

  • Structure and transcriptional regulation of the GFAP gene

    Michael Brenner

  • Multiple interacting sites regulate astrocyte-specific transcription of the human gene for glial fibrillary acidic protein.

    F. Besnard;M. Brenner;Y. Nakatani;R. Chao

  • High susceptibility to cerebral ischemia in GFAP-null mice.

    Hiroshi Nawashiro;Michael Brenner;Shinji Fukui;Katsuji Shima

  • Global forebrain ischemia results in differential cellular expression of interleukin-1beta (IL-1beta) and its receptor at mRNA and protein level.

    Tiina R Sairanen;Perttu J Lindsberg;Perttu J Lindsberg;Michael Brenner;Anna-Leena Sirén

  • Infantile Alexander disease: spectrum of GFAP mutations and genotype-phenotype correlation.

    Diana Rodriguez;Fernande Gauthier;Enrico Bertini;Marianna Bugiani

  • GFAP mutations in Alexander disease.

    Rong Li;Albee Messing;James E. Goldman;Michael Brenner

  • Conditional Ablation of Cerebellar Astrocytes in Postnatal Transgenic Mice

    Catherine L. Delaney;Michael Brenner;Albee Messing

  • The Alexander Disease–Causing Glial Fibrillary Acidic Protein Mutant, R416W, Accumulates into Rosenthal Fibers by a Pathway That Involves Filament Aggregation and the Association of αB-Crystallin and HSP27

    Ming Der Perng;Mu Su;Shu Fang Wen;Rong Li

  • Cryogenic spinal cord injury induces astrocytic gene expression of insulin-like growth factor I and insulin-like growth factor binding protein 2 during myelin regeneration.

    Yao Dl;West Nr;Bondy Ca;Brenner M

Frequent Co-Authors

Albee Messing
Albee Messing University of Wisconsin–Madison
James E. Goldman
James E. Goldman Columbia University
John M. Hallenbeck
John M. Hallenbeck National Institutes of Health
Roy A. Quinlan
Roy A. Quinlan Durham University
Henry deF. Webster
Henry deF. Webster National Institutes of Health
Ernst Freese
Ernst Freese MRC Laboratory of Molecular Biology
Carolyn A. Bondy
Carolyn A. Bondy National Institutes of Health
Rob C. Hoeben
Rob C. Hoeben Leiden University Medical Center
Jun-ichi Tomizawa
Jun-ichi Tomizawa National Institute of Genetics

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