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D-Index & Metrics

Biology and Biochemistry

D-Index
42
Citations
5402
World Ranking
19511
National Ranking
1509

Overview

Matthias Brock is affiliated with the University of Nottingham in the United Kingdom. Their academic work primarily focuses on Medicine, with notable specialization in subfields such as Epidemiology, Infectious Diseases, Oncology, Plant Science, and Pharmacology.

The scientist's research topics broadly cover:

  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Fungal Biology and Applications
  • Mycotoxins in Agriculture and Food
  • Plant Pathogens and Fungal Diseases
  • CAR-T cell therapy research
  • Antimicrobial Peptides and Activities

Matthias Brock has authored several papers in collaboration with frequent co-authors, including Roberta Peres da Silva, Stefan Warmuth, Tea Gunde, Daniel Snell, and Christian Hess.

Some recent publications include:

  • New colours for old in the blue-cheese fungus Penicillium roqueforti (2024) in npj Science of Food
  • Longitudinal multimodal imaging-compatible mouse model of triazole-sensitive and -resistant invasive pulmonary aspergillosis (2022) in Disease Models & Mechanisms
  • Engineering of a trispecific tumor-targeted immunotherapy incorporating 4-1BB co-stimulation and PD-L1 blockade (2021) in OncoImmunology
  • Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model (2021) in Virulence
  • Propionate metabolism in a human pathogenic fungus: proteomic and biochemical analyses (2020) in IMA Fungus

Frequent venues for their publications encompass Cancer Research, Microbiology Spectrum, Fungal Biology, IMA Fungus, and Virulence, highlighting a consistent engagement with journals that focus on medical and fungal research.

Best Publications

  • Candida albicans Scavenges Host Zinc via Pra1 during Endothelial Invasion

    Francesco Citiulo;Ilse D. Jacobsen;Pedro Miramón;Lydia Schild

  • On the mechanism of action of the antifungal agent propionate.

    Matthias Brock;Wolfgang Buckel

  • Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein.

    Marc Hetzel;Matthias Brock;Thorsten Selmer;Antonio J. Pierik

  • Oxidation of propionate to pyruvate in Escherichia coli. Involvement of methylcitrate dehydratase and aconitase.

    Matthias Brock;Claudia Maerker;Alexandra Schütz;Uwe Völker;Uwe Völker

  • Bioluminescent Aspergillus fumigatus, a New Tool for Drug Efficiency Testing and In Vivo Monitoring of Invasive Aspergillosis

    Matthias Brock;Grégory Jouvion;Sabrina Droin-Bergère;Olivier Dussurget

  • Deletion of the Aspergillus fumigatus lysine biosynthesis gene lysF encoding homoaconitase leads to attenuated virulence in a low-dose mouse infection model of invasive aspergillosis

    Burghard Liebmann;Thomas W. Mühleisen;Meike Müller;Matthias Hecht

  • A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress

    Elena Geib;Elena Geib;Markus Gressler;Iuliia Viediernikova;Falk Hillmann

  • Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages.

    Silvia Slesiona;Markus Gressler;Michael Mihlan;Christoph Zaehle

  • Fungal metabolism in host niches.

    Matthias Brock

  • Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans.

    Judith Behnsen;Priyanka Narang;Mike Hasenberg;Frank Gunzer

  • Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus

    Venelina Sugareva;Venelina Sugareva;Albert Härtl;Matthias Brock;Matthias Brock;Katrin Hübner;Katrin Hübner

  • Multifactorial Induction of an Orphan PKS-NRPS Gene Cluster in Aspergillus terreus

    Markus Gressler;Christoph Zaehle;Kirstin Scherlach;Christian Hertweck;Christian Hertweck

  • Terrein Biosynthesis in Aspergillus terreus and Its Impact on Phytotoxicity

    Christoph Zaehle;Markus Gressler;Ekaterina Shelest;Elena Geib

  • Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis.

    Oumaïma Ibrahim-Granet;Marc Dubourdeau;Jean-Paul Latgé;Patrick Ave

  • Methylcitrate synthase from Aspergillus nidulans: implications for propionate as an antifungal agent

    Matthias Brock;Reinhard Fischer;Reinhard Fischer;Dietmar Linder;Wolfgang Buckel

  • Nutrient acquisition by pathogenic fungi: Nutrient availability, pathway regulation, and differences in substrate utilization

    Christian B. Fleck;Felicitas Schöbel;Matthias Brock

  • A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster

    Markus Gressler;Peter Hortschansky;Elena Geib;Matthias Brock;Matthias Brock

  • In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

    Oumaïma Ibrahim-Granet;Grégory Jouvion;Tobias M Hohl;Tobias M Hohl;Sabrina Droin-Bergère

  • Embryonated Eggs as an Alternative Infection Model To Investigate Aspergillus fumigatus Virulence

    Ilse D. Jacobsen;Katharina Grosse;Silvia Slesiona;Bernhard Hube

  • An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein

    Marc Hetzel;Matthias Brock;Thorsten Selmer;Antonio J. Pierik

Frequent Co-Authors

Bernhard Hube
Bernhard Hube Leibniz Association
Ilse D. Jacobsen
Ilse D. Jacobsen Leibniz Association
Axel A. Brakhage
Axel A. Brakhage Leibniz Association
Wolfgang Buckel
Wolfgang Buckel Philipp University of Marburg
Christian Hertweck
Christian Hertweck Friedrich Schiller University Jena
Jean-Marc Cavaillon
Jean-Marc Cavaillon Institut Pasteur
Guilhem Janbon
Guilhem Janbon Institut Pasteur
Reinhard Fischer
Reinhard Fischer Karlsruhe Institute of Technology
Gustavo H. Goldman
Gustavo H. Goldman Universidade de São Paulo

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