World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
43
Citations
6359
World Ranking
17273
National Ranking
685

Biology and Biochemistry

D-Index
52
Citations
8950
World Ranking
16755
National Ranking
529

Overview

Massimo Castagnola is affiliated with the Catholic University of the Sacred Heart in Italy. Their research spans fields primarily in Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on several interrelated subfields and topics.

The main subfields of study include Molecular Biology, Physiology, Cell Biology, Oncology, and Pulmonary and Respiratory Medicine. Their work often intersects with topics such as Salivary Gland Disorders and Functions, S100 Proteins and Annexins, Oral microbiology and periodontitis research, Antimicrobial Peptides and Activities, Iron Metabolism and Disorders, Cellular Mechanics and Interactions, and Alzheimer's disease research and treatments.

Among recent publications, several papers demonstrate the breadth of Castagnola's research interests and contributions:

  • "Saliva, a bodily fluid with recognized and potential diagnostic applications," 2021, Journal of Separation Science
  • "Molecular pathways triggered by COVID-19 in different organs: ACE2 receptor-expressing cells under attack? A review," 2020, PubMed
  • "Multiple Herpes Simplex Virus-1 (HSV-1) Reactivations Induce Protein Oxidative Damage in Mouse Brain: Novel Mechanisms for Alzheimer's Disease Progression," 2020, Microorganisms
  • "Top-Down Proteomics of Human Saliva Highlights Anti-inflammatory, Antioxidant, and Antimicrobial Defense Responses in Alzheimer Disease," 2021, Frontiers in Neuroscience
  • "Thymosin β4 Is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis," 2022, International Journal of Molecular Sciences

Frequent co-authors in Castagnola's body of work reflect a collaborative research environment. These include Federica Iavarone, Irene Messana, Tiziana Cabras, Gavino Faa, and Alessandra Olianas, each contributing to a significant number of joint publications.

Research outputs are commonly published in journals such as the International Journal of Molecular Sciences, PubMed, Annals of Research in Oncology, Cancers, and Frontiers in Neuroscience. This distribution indicates a strong presence in both molecular biology and clinical oncology research domains.

Best Publications

  • The Multiple Functions of Hemoglobin

    Bruno Giardina;Irene Messana;Roberto Scatena;Massimo Castagnola

  • Facts and artifacts in proteomics of body fluids. What proteomics of saliva is telling us

    Irene Messana;Rosanna Inzitari;Chiara Fanali;Tiziana Cabras

  • Salivary biomarkers and proteomics: future diagnostic and clinical utilities.

    Massimo Castagnola;E Scarano;Gc Passali;Irene Messana

  • Proteomic approach in the identification of fertility pattern in seminal plasma of fertile men

    Domenico Milardi;Giuseppe Grande;Federica Vincenzoni;Irene Messana

  • Saliva and the Control of Its Secretion

    Jörgen Ekström;Nina Khosravani;Massimo Castagnola;Irene Messana

  • Human erythrocyte metabolism is modulated by the O2-linked transition of hemoglobin

    Irene Messana;Mario Orlando;Loredana Cassiano;Lucia Pennacchietti

  • Trafficking and Postsecretory Events Responsible for the Formation of Secreted Human Salivary Peptides A Proteomics Approach

    Irene Messana;Tiziana Cabras;Elisabetta Pisano;Maria Teresa Sanna

  • A cascade of 24 histatins (histatin 3 fragments) in human saliva: suggestions for a pre-secretory sequential cleavage pathway

    Massimo Castagnola;Rosanna Inzitari;Diana Valeria Rossetti;Chiara Olmi

  • Proteomic study of salivary peptides and proteins in patients with Sjögren's syndrome before and after pilocarpine treatment

    G. Peluso;M. De Santis;R. Inzitari;C. Fanali

  • Blood bank conditions and RBCs: the progressive loss of metabolic modulation

    I. Messana;L. Ferroni;F. Misiti;G. Girelli

  • Characterization of the human salivary basic proline-rich protein complex by a proteomic approach.

    Irene Messana;Tiziana Cabras;Rosanna Inzitari;Alessandro Lupi

  • Responsiveness to 6-n-Propylthiouracil (PROP) Is Associated with Salivary Levels of Two Specific Basic Proline-Rich Proteins in Humans

    Tiziana Cabras;Melania Melis;Massimo Castagnola;Alessandra Padiglia

  • Peptides of human gingival crevicular fluid determined by HPLC-ESI-MS.

    Elisabetta Pisano;Tiziana Cabras;Caterina Montaldo;Vincenzo Piras

  • Globular structure of human ovulatory cervical mucus

    Roberto Brunelli;Massimiliano Papi;Giuseppe Arcovito;Adriano Bompiani

  • Alterations of the salivary secretory peptidome profile in children affected by type 1 diabetes

    Tiziana Cabras;Elisabetta Pisano;Andrea Mastinu;Gloria Denotti

  • Age-dependent modifications of the human salivary secretory protein complex

    Tiziana Cabras;Elisabetta Pisano;Roberto Boi;Alessandra Olianas

  • Biotechnological implications of the salivary proteome

    Massimo Castagnola;Tiziana Cabras;Alberto Vitali;Maria Teresa Sanna

  • Peptide analysis by capillary (zone) electrophoresis.

    Irene Messana;Diana Valeria Rossetti;Loredana Cassiano;Francesco Misiti

  • Hypo-Phosphorylation of Salivary Peptidome as a Clue to the Molecular Pathogenesis of Autism Spectrum Disorders

    Massimo Castagnola;Irene Messana;Rosanna Inzitari;Chiara Fanali

  • Cord blood mononuclear cell responsiveness to beta-lactoglobulin : T-cell activity in atopy-prone and non-atopy-prone newborns

    Marco Piastra;Achille Stabile;Giuseppina Fioravanti;Massimo Castagnola

  • Proteomics of human seminal plasma: identification of biomarker candidates for fertility and infertility and the evolution of technology.

    Domenico Milardi;Giuseppe Grande;Federica Vincenzoni;Massimo Castagnola

Frequent Co-Authors

Bruno Giardina
Bruno Giardina Catholic University of the Sacred Heart
Giulia Morace
Giulia Morace University of Milan
Luciano Polonelli
Luciano Polonelli University of Parma
Renato Longhi
Renato Longhi National Academies of Sciences, Engineering, and Medicine
Mauro Fasano
Mauro Fasano University of Insubria
Giuseppe Leone
Giuseppe Leone Catholic University of the Sacred Heart
Gianfranco Ferraccioli
Gianfranco Ferraccioli Catholic University of the Sacred Heart
Antonio Bianconi
Antonio Bianconi Rome International Centre Materials Science Superstripes
Andrea Urbani
Andrea Urbani University of Padua
Francisco Amado
Francisco Amado University of Aveiro

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring biology and biochemistry can open doors to diverse careers in healthcare and research. Students interested in health and nutrition may want to consider the best dietetics programs to gain expertise in food science and clinical nutrition.

For those drawn to clinical settings, starting with medical assistant courses online can provide foundational skills and fast-track entry into the medical field. If you’re already a medical assistant, the ma to lpn bridge program offers a pathway for career advancement and increased responsibilities.

For those seeking flexibility, the rise of online biology degree options makes it easier to balance studies with work or family commitments. Accelerated programs can help you graduate sooner and enter the workforce or further study with less delay.

Whether you plan to support patient care, specialize in nutrition, or conduct advanced research, these online pathways can help you reach your professional goals in the biological sciences.

Best Scientists Citing Massimo Castagnola

Trending Scientists

Recently Published Articles