World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
45
Citations
6834
World Ranking
19146
National Ranking
1307

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Manfred Schweiger is affiliated with Freie Universität Berlin in Germany and has contributed extensively to the fields of biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their research spans various subfields including molecular biology, genetics, pathology and forensic medicine, cancer research, and surgery.

Their publication record includes studies in well-recognized journals, frequently appearing in the International Journal of Molecular Sciences, Cells, Blood, and Angewandte Chemie International Edition. The venues include:

  • International Journal of Molecular Sciences
  • Cells
  • Blood
  • Angewandte Chemie International Edition
  • Angewandte Chemie

Key research topics covered by Schweiger involve epigenetics and DNA methylation, chronic lymphocytic leukemia research, RNA modifications and cancer, genomics and chromatin dynamics, gastrointestinal motility and disorders, Helicobacter pylori-related gastroenterology studies, and virus-based gene therapy research.

  • Epigenetics and DNA Methylation
  • Chronic Lymphocytic Leukemia Research
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • Gastrointestinal motility and disorders
  • Helicobacter pylori-related gastroenterology studies
  • Virus-based gene therapy research

Recent publications by Schweiger include:

  • "Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies," 2022, Blood
  • "Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming," 2020, Scientific Reports
  • "Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells," 2020, Oncogene
  • "Light-Activation of DNA-Methyltransferases," 2021, Angewandte Chemie International Edition
  • "Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M)," 2023, Cells

Frequent collaborators in Schweiger's research network include:

  • Christina Grimm
  • Margarete Odenthal
  • Carmen Herling
  • Michael Hallek
  • Álvaro Muñoz-López

Manfred Schweiger is recognized as a member of the European Molecular Biology Organization (EMBO), indicating a level of engagement with the molecular biology research community in Europe.

Best Publications

  • Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

    Zhao-Qi Wang;B. Auer;L. Stingl;H. Berghammer

  • A novel modular mosaic of cell adhesion motifs in the extracellular domains of the neurogenic trk and trkB tyrosine kinase receptors.

    R Schneider;M Schweiger

  • Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis.

    Manfred Schweiger;Klaus Hennig;Felicitas Lerner;Marc Niere

  • Protein kinase induction in Escherichia coli by bacteriophage T7.

    H. J. Rahmsdorf;S. H. Pai;P. Ponta;P. Herrlich

  • Regulation of RNA Polymerase II-dependent Transcription by Poly(ADP-ribosyl)ation of Transcription Factors

    Shiao Li Oei;Joachim Griesenbeck;Manfred Schweiger;Mathias Ziegler

  • Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria.

    Andrés Herrero‐Yraola;Siham M.A. Bakhit;Peter Franke;Christoph Weise

  • Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes.

    H. Weirich-Schwaiger;H.G. Weirich;B. Gruber;M. Schweiger

  • In vivo and in vitro phosphorylation of DNA-dependent RNA polymerase of Escherichia coli by bacteriophage-T7-induced protein kinase.

    Wolfram Zillig;Hirota Fujiki;Werner Blum;Davorin Janekovic

  • Interaction of the Transcription Factor YY1 with Human Poly(ADP-Ribosyl) Transferase

    Shiao Li Oei;Joachim Griesenbeck;Manfred Schweiger;Victor Babich

  • In vitro Synthesis, Termination, and Release of Active Messenger RNA

    Robert L. Millette;Carol D. Trotter;Peter Herrlich;Manfred Schweiger

  • The role of poly(ADP-ribosyl)ation.

    S. L. Oei;J. Griesenbeck;M. Schweiger

  • The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module.

    R Schneider;E Schneider-Scherzer;M Thurnher;B Auer

  • Fraktionierung der iöslichen ribonucleinsäure

    Hans Georg Zachau;Mitsuhiko Tada;William B. Lawson;Manfred Schweiger

  • A human ubiquitin-conjugating enzyme homologous to yeast UBC8.

    P Kaiser;W Seufert;L Höfferer;B Kofler

  • SYNTHESIS OF PHAGE-SPECIFIC α- AND β-GLUCOSYL TRANSFERASES DIRECTED BY T-EVEN DNA in vitro

    Lawrence M. Gold;Manfred Schweiger

  • Isolation of ADP-ribosyltransferase by affinity chromatography.

    Helmut J. Burtscher;Bernhard Auer;Helmut Klocker;Manfred Schweiger

  • A Novel Function of Poly(ADP-ribosyl)ation: Silencing of RNA Polymerase II-Dependent Transcription†

    Shiao Li Oei;Joachim Griesenbeck;Mathias Ziegler;Manfred Schweiger

  • Control of gene expression in bacteriophage T7: Transcriptional controls

    H. Ponta;H. J. Rahmsdorf;S. H. Pai;M. Hirsch-Kauffmann

  • BACTERIOPHAGE T4 DNA-DEPENDENT in vitro SYNTHESIS OF LYSOZYME

    Manfred Schweiger;Lawrence M. Gold

  • Overexpression of thioredoxin in Fanconi anemia fibroblasts prevents the cytotoxic and DNA damaging effect of mitomycin C and diepoxybutane

    Werner Ruppitsch;Claudia Meißlitzer;Monica Hirsch-Kauffmann;Manfred Schweiger

Frequent Co-Authors

Erwin F. Wagner
Erwin F. Wagner Medical University of Vienna
Mathias Ziegler
Mathias Ziegler University of Bergen
Peter Herrlich
Peter Herrlich Leibniz Association
Herbert Herzog
Herbert Herzog Garvan Institute of Medical Research
Udo Heinemann
Udo Heinemann Max Delbrück Center for Molecular Medicine
Helmut Ponta
Helmut Ponta Karlsruhe Institute of Technology
Wolfram Zillig
Wolfram Zillig Max Planck Society
Peter K. Kaiser
Peter K. Kaiser Cleveland Clinic
Christoph Weise
Christoph Weise Freie Universität Berlin
Hans G. Zachau
Hans G. Zachau Ludwig-Maximilians-Universität München

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