World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
48
Citations
10545
World Ranking
15090
National Ranking
1100

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Luciano Mueller is affiliated with Bristol-Myers Squibb (Germany) in Germany and has a research focus across multiple areas in biochemistry, genetics, molecular biology, and medicine. Their work spans key subfields including molecular biology, computational theory and mathematics, radiology and nuclear medicine, immunology, and public health, environmental and occupational health.

Mueller's recent publications cover a range of topics relevant to molecular and computational drug discovery, protein structure, immunology, and chemical analysis. Recent papers include:

  • "Perspectives on Nuclear Magnetic Resonance Spectroscopy in Drug Discovery Research," 2024, Journal of Medicinal Chemistry
  • "Ranking mAb-excipient interactions in biologics formulations by NMR spectroscopy and computational approaches," 2023, mAbs
  • "Complex peptide macrocycle optimization: combining NMR restraints with conformational analysis to guide structure-based and ligand-based design," 2023, Journal of Computer-Aided Molecular Design
  • "Orthosteric STING inhibition elucidates molecular correction of SAVI STING," 2025, Nature Communications
  • "THz-Driven Coherent Magnetization Dynamics in a Labyrinth Domain State," 2023, arXiv (Cornell University)

Their collaborative network includes frequent coauthors such as Janet Caceres-Cortes, Bradley T. Falk, Ajay N. Jain, Alexander C. Brueckner, and Christine Jorge, reflecting engagements in multidisciplinary teams.

Mueller's publications are concentrated in journals including:

  • Journal of Computer-Aided Molecular Design
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Medicinal Chemistry
  • mAbs
  • Nature Communications

The main research topics by which Mueller's work can be classified include:

  • Protein Structure and Dynamics
  • Computational Drug Discovery Methods
  • Monoclonal and Polyclonal Antibodies Research
  • Chemical Synthesis and Analysis
  • Interferon and Immune Responses
  • Mosquito-borne Diseases and Control
  • Biochemical and Molecular Research

Over the years, Mueller's contributions have been recognized through awards such as the Fellowship of the American Association for the Advancement of Science (AAAS) granted in 2018.

Best Publications

  • Sensitivity enhanced detection of weak nuclei using heteronuclear multiple quantum coherence

    Luciano Mueller

  • Tunable alignment of macromolecules by filamentous phage yields dipolar coupling interactions

    Mark R. Hansen;Luciano Mueller;Arthur Pardi

  • The Dynamic Process of β2-Adrenergic Receptor Activation

    Rie Nygaard;Yaozhong Zou;Ron O. Dror;Thomas J. Mildorf

  • Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

    Michael P. Bokoch;Yaozhong Zou;Søren G F Rasmussen;Corey W. Liu

  • Localizing the NADP+ binding site on the MurB enzyme by NMR.

    Bennett T. Farmer;Keith L. Constantine;Valentina Goldfarb;Mark S. Friedrichs

  • P.E.COSY, a simple alternative to E.COSY

    Unknown

  • The Dynamic Process of b 2 -Adrenergic Receptor Activation

    Rie Nygaard;Yaozhong Zou;Ron O. Dror;Thomas J. Mildorf

  • Solution structure of human CTLA-4 and delineation of a CD80/CD86 binding site conserved in CD28.

    William J. Metzler;Jürgen Bajorath;William Fenderson;Shyh Yu Shaw

  • Selective shaped pulse decoupling in NMR: homonuclear [carbon-13]carbonyl decoupling

    Unknown

  • Characterization of the three-dimensional solution structure of human profilin : 1H, 13C, and 15N NMR assignments and global folding pattern

    William Metzler;Keith Constantine;Mark Friedrichs;Aneka Bell

  • Sequential 1H NMR Assignments and Secondary Structure Identification of Human Ubiquitin

    Paul L. Weber;Stephen C. Brown;Luciano Mueller

  • 1H, 13C, and 15N NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins.

    Michael Wittekind;Matthias Gorlach;Mark Friedrichs;Gideon Dreyfuss

  • Characterization of the three-dimensional solution structure of human profilin: proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern

    William J. Metzler;Keith L. Constantine;Mark S. Friedrichs;Aneka J. Bell

  • Use of 1HN-1HN NOEs to Determine Protein Global Folds in Perdeuterated Proteins

    Ronald A. Venters;William J. Metzler;Leonard D. Spicer;Luciano Mueller

  • The Discovery of Asunaprevir (BMS-650032), An Orally Efficacious NS3 Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

    Paul M. Scola;Li-Qiang Sun;Alan Xiangdong Wang;Jie Chen

  • Identification of the poly-L-proline-binding site on human profilin.

    W J Metzler;A J Bell;E Ernst;T B Lavoie

  • Improved RNA Structure Determination by Detection of NOE Contacts to Exchange-Broadened Amino Protons

    Luciano Mueller;Pascale Legault;Arthur Pardi

  • NMR identification of protein surfaces using paramagnetic probes.

    Andrew M. Petros;Luciano Mueller;Kenneth D. Kopple

  • Characterization of a new four-chain coiled-coil: Influence of chain length on stability

    Robert Fairman;Hann-Guang Chao;Luciano Mueller;Thomas B. Lavoie

  • Incorporation of 1H/13C/15N-{Ile, Leu, Val} into a Perdeuterated, 15N-Labeled Protein: Potential in Structure Determination of Large Proteins by NMR

    William J. Metzler;Michael Wittekind;Valentina Goldfarb;Luciano Mueller

  • Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy.

    Michael Wittekind;Claudio Mapelli;Bennett T. Farmer;Ki-Ling Suen

  • Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.

    Michael Wittekind;Claudio Mapelli;Ving Lee;Valentina Goldfarb

Frequent Co-Authors

Arthur Pardi
Arthur Pardi University of Colorado Boulder
Brian K. Kobilka
Brian K. Kobilka Stanford University
Nicholas A. Meanwell
Nicholas A. Meanwell Bristol-Myers Squibb (Germany)
Lewis E. Kay
Lewis E. Kay University of Toronto
David G. Marsh
David G. Marsh Johns Hopkins University
Leonardo Pardo
Leonardo Pardo Autonomous University of Barcelona
David E. Shaw
David E. Shaw D. E. Shaw Research
Michael L. Gross
Michael L. Gross Washington University in St. Louis
Peter S. Linsley
Peter S. Linsley Benaroya Research Institute
Marco M. Gottardis
Marco M. Gottardis NKGen Biotech Inc

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