World's Best Scientists 2026 revealed!
Liana G. Apostolova

Liana G. Apostolova

D-Index & Metrics

Neuroscience

D-Index
77
Citations
33500
World Ranking
1799
National Ranking
865

Overview

Liana G. Apostolova is affiliated with Indiana University in the United States and specializes in medical research, with a principal focus on neurodegenerative diseases and cognitive disorders. Their scholarly output largely concentrates on the study of dementia, Alzheimer's disease, and the neurological mechanisms underlying cognitive decline.

Their research spans multiple subfields of medicine, including:

  • Psychiatry and Mental health
  • Physiology
  • Cognitive Neuroscience
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging

The main topics addressed in their work include:

  • Dementia and Cognitive Impairment Research
  • Alzheimer's disease research and treatments
  • Functional Brain Connectivity Studies
  • Advanced Neuroimaging Techniques and Applications
  • Bioinformatics and Genomic Networks
  • Health, Environment, Cognitive Aging
  • Genetic Associations and Epidemiology

Recent publications highlight contributions to key studies in Alzheimer's disease and related fields. Some notable papers by Apostolova include:

  • "Donanemab in Early Symptomatic Alzheimer Disease", 2023, published in JAMA
  • "Donanemab in Early Alzheimer's Disease", 2021, published in New England Journal of Medicine
  • "New insights into atypical Alzheimer's disease in the era of biomarkers", 2021, published in The Lancet Neurology
  • "Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study", 2020, published in Nature Communications
  • "Aducanumab: Appropriate Use Recommendations", 2021, published in The Journal of Prevention of Alzheimer s Disease

Their research has been disseminated primarily through frequent publication in venues such as:

  • Alzheimer s & Dementia (123 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (10 publications)
  • Journal of Alzheimer s Disease (6 publications)
  • JAMA Neurology (5 publications)
  • Brain (4 publications)

Collaborations have been a significant part of their career, with frequent coauthors including researchers who have contributed extensively in the field of Alzheimer's and cognitive neuroscience. Notable coauthors are:

  • Andrew J. Saykin
  • Gil D. Rabinovici
  • Shannon L. Risacher
  • María C. Carrillo
  • Sujuan Gao

Best Publications

  • Donanemab in Early Alzheimer's Disease.

    Mark A Mintun;Albert C Lo;Cynthia Duggan Evans;Alette M Wessels

  • Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

    Y. Iturria-Medina;R. C. Sotero;P. J. Toussaint;J. M. Mateos-Pérez

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

    Paul M. Thompson;Jason L. Stein;Sarah E. Medland;Derrek P. Hibar

  • Identification of common variants associated with human hippocampal and intracranial volumes

    Jason L Stein;Sarah E Medland;Sarah E Medland;Alejandro Arias Vasquez;Alejandro Arias Vasquez;Derrek P Hibar

  • Four distinct trajectories of tau deposition identified in Alzheimer’s disease

    Jacob W Vogel;Alexandra L Young;Neil P Oxtoby;Ruben Smith

  • Conversion of mild cognitive impairment to Alzheimer disease predicted by hippocampal atrophy maps.

    Liana G. Apostolova;Rebecca A. Dutton;Ivo D. Dinov;Kiralee M. Hayashi

  • New insights into atypical Alzheimer's disease in the era of biomarkers.

    Jonathan Graff-Radford;Keir X X Yong;Liana G Apostolova;Femke H Bouwman

  • Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study.

    John M Ringman;Sally A Frautschy;Edmond Teng;Aynun N Begum

  • Neuropsychiatric Manifestations in Mild Cognitive Impairment: A Systematic Review of the Literature

    Liana G. Apostolova;Jeffrey L. Cummings

  • Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

    Jacob W. Vogel;Yasser Iturria-Medina;Olof T. Strandberg;Ruben Smith

  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    Eric M Reiman;Joseph F Arboleda-Velasquez;Yakeel T Quiroz;Matthew J Huentelman

  • Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease

    Unknown

  • Hippocampal atrophy and ventricular enlargement in normal aging, mild cognitive impairment (MCI), and Alzheimer Disease.

    Liana G. Apostolova;Amity E. Green;Sona Babakchanian;Kristy S. Hwang

  • Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal

    Liana G. Apostolova;Lisa Mosconi;Paul M. Thompson;Amity E. Green

  • Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.

    Taylor W. Schmitz;R. Nathan Spreng;Michael W. Weiner;Paul Aisen

  • 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease

    Liana G. Apostolova;Ivo D. Dinov;Rebecca A. Dutton;Kiralee M. Hayashi

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations.

    John M Ringman;Joseph O'Neill;Daniel Geschwind;Luis Medina

  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

    Alzheimer's Disease Neuroimaging Initiative

  • Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls.

    Jonathan H. Morra;Zhuowen Tu;Liana G. Apostolova;Amity E. Green

  • Comparison of AdaBoost and Support Vector Machines for Detecting Alzheimer's Disease Through Automated Hippocampal Segmentation

    J.H. Morra;Zhuowen Tu;L.G. Apostolova;A.E. Green

Frequent Co-Authors

Paul M. Thompson
Paul M. Thompson University of Southern California
Shannon L. Risacher
Shannon L. Risacher Indiana University
Jeffrey L. Cummings
Jeffrey L. Cummings University of Nevada, Las Vegas
Arthur W. Toga
Arthur W. Toga University of Southern California
Clifford R. Jack
Clifford R. Jack Mayo Clinic
Martin R. Farlow
Martin R. Farlow Indiana University
Tatiana Foroud
Tatiana Foroud Indiana University
Michael W. Weiner
Michael W. Weiner University of California, San Francisco
Kwangsik Nho
Kwangsik Nho Indiana University
Charles DeCarli
Charles DeCarli University of California, Davis

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