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Leoni A. Kunz-Schughart

Leoni A. Kunz-Schughart

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
21577
World Ranking
11697
National Ranking
833

Overview

Leoni A. Kunz-Schughart is affiliated with TU Dresden in Germany, with a research focus predominantly in the fields of biochemistry, genetics, and molecular biology, alongside significant contributions to medicine. Their specialized subfields include molecular biology, biotechnology, oncology, biomedical engineering, and cancer research.

The scientist's research encompasses a broad array of topics such as cancer research and treatments, cancer-related hypoxia and metabolism, heat shock proteins, techniques for cell image analysis, cancer cells and metastasis, virus-based gene therapy research, and laser-plasma interactions and diagnostics.

Leoni A. Kunz-Schughart has published numerous papers in various scientific venues. Notable recent publications include:

  • "GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy," 2021, Theranostics
  • "MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity," 2021, Nature Methods
  • "Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer," 2021, Communications Biology
  • "Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline," 2020, SZTE Publicatio Repozitórium (University of Szeged)
  • "Validation of CD98hc as a Therapeutic Target for a Combination of Radiation and Immunotherapies in Head and Neck Squamous Cell Carcinoma," 2022, Cancers

Their frequent publication venues reflect the scope of their research and include:

  • Cancers
  • Scientific Reports
  • arXiv (Cornell University)
  • Theranostics
  • Nature Methods

Collaborations form an integral part of the scientist's work, with repeated co-authors including Soňa Michlíková, Oleg Chen, Anna Dubrovska, Lisa Eckhardt, and Adriana M. De Mendoza. These collaborations contribute to advancing research in a multidisciplinary context.

Best Publications

  • Inhibitory effect of tumor cell–derived lactic acid on human T cells

    Karin Fischer;Petra Hoffmann;Simon Voelkl;Norbert Meidenbauer

  • Multicellular tumor spheroids: an underestimated tool is catching up again

    Franziska Hirschhaeuser;Heike Menne;Claudia Dittfeld;Jonathan West

  • Spheroid-based drug screen: considerations and practical approach

    Juergen Friedrich;Claudia Seidel;Reinhard Ebner;Leoni A Kunz-Schughart

  • Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

    Thomas Brabletz;Andreas Jung;Simone Reu;Marc Porzner

  • The use of 3-D cultures for high-throughput screening: the multicellular spheroid model.

    Leoni A. Kunz-Schughart;James P. Freyer;Ferdinand Hofstaedter;Reinhard Ebner

  • Oxidative Phosphorylation as an Emerging Target in Cancer Therapy

    Thomas M Ashton;W. Gillies McKenna;Leoni A. Kunz-Schughart;Geoff S. Higgins

  • Tumor-derived lactic acid modulates dendritic cell activation and antigen expression

    Eva Gottfried;Leoni A. Kunz-Schughart;Leoni A. Kunz-Schughart;Stephanie Ebner;Stephanie Ebner;Wolfgang Mueller-Klieser;Wolfgang Mueller-Klieser

  • Large-scale in vitro expansion of polyclonal human CD4+CD25high regulatory T cells

    Petra Hoffmann;Ruediger Eder;Leoni A. Kunz-Schughart;Reinhard Andreesen

  • Experimental anti-tumor therapy in 3-D: spheroids--old hat or new challenge?

    Juergen Friedrich;Reinhard Ebner;Leoni A Kunz-Schughart

  • Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes

    Katrin Dietl;Kathrin Renner;Katja Dettmer;Birgit Timischl

  • Multicellular spheroids: a three-dimensional in vitro culture system to study tumour biology.

    Leoni A. Kunz-Schughart;Marina Kreutz;Ruth Knuechel

  • Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release.

    Kristina Goetze;Stefan Walenta;Magdalena Ksiazkiewicz;Leoni A. Kunz-Schughart

  • Temozolomide preferentially depletes cancer stem cells in glioblastoma.

    Dagmar Beier;Stefanie Röhrl;Deepu R. Pillai;Stefanie Schwarz

  • CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges

    Philipp Grosse-Gehling;Christine A Fargeas;Claudia Dittfeld;Yvette Garbe

  • Basophils enhance immunological memory responses.

    Andrea Denzel;Ulrich A Maus;Manuel Rodriguez Gomez;Cordula Moll;Cordula Moll

  • Multicellular tumor spheroids: intermediates between monolayer culture and in vivo tumor.

    Kunz-Schughart La

  • Expression of CD68 in Non-Myeloid Cell Types

    E. Gottfried;L. A. Kunz-Schughart;A. Weber;M. Rehli

  • Aldehyde Dehydrogenase Is Regulated by β-Catenin/TCF and Promotes Radioresistance in Prostate Cancer Progenitor Cells

    Monica Cojoc;Claudia Peitzsch;Ina Kurth;Franziska Trautmann

  • The fibroblast: sentinel cell and local immune modulator in tumor tissue.

    Tobias Silzle;Gwendalyn J. Randolph;Marina Kreutz;Leoni A. Kunz-Schughart

  • A Reliable Tool to Determine Cell Viability in Complex 3-D Culture: The Acid Phosphatase Assay

    Juergen Friedrich;Wolfgang Eder;Juana Castaneda;Markus Doss

Frequent Co-Authors

Reinhard Andreesen
Reinhard Andreesen University of Regensburg
Marina Kreutz
Marina Kreutz University of Regensburg
Reinhard Ebner
Reinhard Ebner Human Genome Sciences (United States)
Arndt Hartmann
Arndt Hartmann University of Erlangen-Nuremberg
Thomas Ried
Thomas Ried National Institutes of Health
Ulrich Bogdahn
Ulrich Bogdahn University of Regensburg
Peter J. Wild
Peter J. Wild Frankfurt Institute for Advanced Studies
Andreas Mackensen
Andreas Mackensen University of Erlangen-Nuremberg
Anja-Katrin Bosserhoff
Anja-Katrin Bosserhoff University of Erlangen-Nuremberg
Matthias Mack
Matthias Mack University of Regensburg

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