World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
8544
World Ranking
17682
National Ranking
7251

Overview

Lawrence Sweetman was affiliated with the University of California, San Diego in the United States. Their research activity was primarily situated within the broad domain of Biochemistry, Genetics and Molecular Biology, reflecting work in several specialized subfields.

The subfields of study that featured in their research included Clinical Biochemistry, Molecular Biology, and Physiology. These areas framed Sweetman's contributions, which often intersected across biochemical and physiological processes at molecular levels.

The main topics addressed in their work encompassed Metabolism and Genetic Disorders, Metabolomics and Mass Spectrometry Studies, and Diet and Metabolism Studies. This thematic focus indicated an emphasis on how metabolic pathways and genetic factors influence health, monitored and analyzed through advanced metabolomic techniques.

Sweetman had published research articles in respected venues, notably including:

  • Quantitative Organic Acids in Urine by Two-Dimensional Gas Chromatography-Time-of-Flight Mass Spectrometry (GCxGC-TOFMS), 2022, Methods in molecular biology
  • Psoas Muscle Cross-Sectional Area and Outcomes Following Colorectal Cancer Surgery, 2022, British Journal Of Surgical Science

Their research collaborations involved several frequent coauthors, indicating a network of scientific partnerships:

  • Erland Arning
  • Paula Ashcraft
  • Jeanna Bennett-Firmin
  • Matthew Mouat
  • Ashok Gunawardene

Sweetman's documented outputs included studies in metabolomics that utilized gas chromatography and mass spectrometry techniques to analyze organic acids, relevant to metabolic profiling.

In another line of investigation, their work examined clinical outcomes related to muscle morphology, specifically the psoas muscle cross-sectional area, in the context of colorectal cancer surgery, linking anatomical measurements to surgical prognoses.

Best Publications

  • Mutations in BCKD-kinase Lead to a Potentially Treatable Form of Autism with Epilepsy

    Gaia Novarino;Paul El-Fishawy;Hulya Kayserili;Nagwa A. Meguid

  • Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride

    Charles R. Roe;Lawrence Sweetman;Diane S. Roe

  • Glutaric aciduria Type II

    Lawrence Sweetman;William L. Nyhan;Doris A. Trauner;T. Allen Merritt

  • Inhibition by propionyl-coenzyme A of N-acetylglutamate synthetase in rat liver mitochondria. A possible explanation for hyperammonemia in propionic and methylmalonic acidemia.

    Francois X. Coude;Lawrence Sweetman;William L. Nyhan

  • Mevalonic aciduria--an inborn error of cholesterol and nonsterol isoprene biosynthesis.

    Georg Hoffmann;Georg Hoffmann;Kenneth M. Gibson;Kenneth M. Gibson;Ira K. Brandt;Ira K. Brandt;Patricia I. Bader;Patricia I. Bader

  • Multiple biotin-dependent carboxylase deficiencies associated with defects in T-cell and B-cell immunity

    Morton J. Cowan;Seymour Packman;Diane W. Wara;Arthur J. Ammann

  • Short-chain acyl-coenzyme A dehydrogenase deficiency. Clinical and biochemical studies in two patients.

    B A Amendt;C Greene;L Sweetman;J Cloherty

  • Mutant holocarboxylase synthetase: evidence for the enzyme defect in early infantile biotin-responsive multiple carboxylase deficiency.

    B J Burri;L Sweetman;W L Nyhan

  • Deficiency of propionyl-CoA carboxylase and methylcrotonyl-CoA carboxylase in a patient with methylcrotonylglycinuria

    Walter Weyler;Lawrence Sweetman;Dominic C. Maggio;William L. Nyhan

  • Propionic acidemia: A clinical update

    Barry Wolf;Y. Edward Hsia;Lawrence Sweetman;Roy Gravel

  • Increased Anion Gap Metabolic Acidosis as a Result of 5-Oxoproline (Pyroglutamic Acid): A Role for Acetaminophen

    Andrew Z. Fenves;Haskell M. Kirkpatrick;Viralkumar V. Patel;Lawrence Sweetman

  • Stable isotope dilution analysis of 4-hydroxybutyric acid: an accurate method for quantification in physiological fluids and the prenatal diagnosis of 4-hydroxybutyric aciduria.

    K. M. Gibson;S. Aramaki;L. Sweetman;W. L. Nyhan

  • 2-Methylbutyryl-coenzyme A dehydrogenase deficiency : A new inborn error of L-isoleucine metabolism

    K Michael Gibson;Terry G Burlingame;Boris Hogema;Cornelis Jakobs

  • Heterogeneity of holocarboxylase synthetase in patients with biotin-responsive multiple carboxylase deficiency.

    B J Burri;L Sweetman;W L Nyhan

  • Biotin-responsive carboxylase deficiency associated with subnormal plasma and urinary biotin.

    Jess Thoene;Herman Baker;Makoto Yoshino;Lawrence Sweetman

  • ISOLATED ISOBUTYRYL-COA DEHYDROGENASE DEFICIENCY : AN UNRECOGNIZED DEFECT IN HUMAN VALINE METABOLISM

    Charles R. Roe;Stephen D. Cederbaum;Diane S. Roe;Rebecca Mardach

  • Succinic semialdehyde dehydrogenase deficiency: an inborn error of gamma-aminobutyric acid metabolism

    Kenneth M. Gibson;Lawrence Sweetman;William L. Nyhan;Cornells Jakobs

  • Abnormal metabolites of isoleucine in a patient with propionyl-CoA carboxylase deficiency.

    Lawrence Sweetman;Walter Weyler;William L. Nyhan;Carlos de Céspedes

  • 3-Hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured fibroblasts from patients with mevalonate kinase deficiency: differential response to lipid supplied by fetal bovine serum in tissue culture medium.

    K M Gibson;G Hoffmann;A Schwall;R L Broock

  • Newborn Screening by Tandem Mass Spectrometry: Gaining Experience

    Lawrence Sweetman

Frequent Co-Authors

William L. Nyhan
William L. Nyhan University of California, San Diego
Georg F. Hoffmann
Georg F. Hoffmann University Hospital Heidelberg
Brian H. Robinson
Brian H. Robinson Hospital for Sick Children
Marinus Duran
Marinus Duran University of Amsterdam
David S. Millington
David S. Millington Duke University
Doris A. Trauner
Doris A. Trauner University of California, San Diego
Morton J. Cowan
Morton J. Cowan University of California, San Francisco
Takashi Hashimoto
Takashi Hashimoto Shinshu University
Jerry Vockley
Jerry Vockley University of Pittsburgh
Seiji Yamaguchi
Seiji Yamaguchi Shimane University

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