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Klaus Fassbender

Klaus Fassbender

D-Index & Metrics

Neuroscience

D-Index
85
Citations
24412
World Ranking
1344
National Ranking
117

Overview

Klaus Fassbender is affiliated with Saarland University in Germany. Their research focuses primarily on Medicine, with a significant emphasis on Neurology, Epidemiology, Molecular Biology, Physiology, and Rehabilitation.

The primary topics covered by their work include:

  • Acute Ischemic Stroke Management
  • Stroke Rehabilitation and Recovery
  • Alzheimer's Disease Research and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Parkinson's Disease Mechanisms and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Neuroinflammation and Neurodegeneration Mechanisms

Fassbender has published extensively in various scientific venues. Frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Neurology
  • Alzheimer's & Dementia
  • Journal of Neurology
  • Journal of the Neurological Sciences

They have collaborated regularly with key coauthors such as Silke Walter, Johannes Kornhuber, Janine Diehl-Schmid, Johannes Prudlo, and Markus Otto.

Several recent papers highlight Fassbender's research contributions:

  • Prehospital Stroke Management in the Thrombectomy Era, 2020, published in The Lancet Neurology
  • Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells, 2020, Cell Reports Medicine
  • Decreased pH in the Aging Brain and Alzheimer's Disease, 2021, Neurobiology of Aging
  • Effects of Resistant Starch on Symptoms, Fecal Markers, and Gut Microbiota in Parkinson's Disease - The RESISTA-PD Trial, 2021, Genomics Proteomics & Bioinformatics
  • Comparison of Mobile Stroke Unit With Usual Care for Acute Ischemic Stroke Management, 2022, JAMA Neurology

Best Publications

  • Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

    K. Fassbender;M. Simons;C. Bergmann;M. Stroick

  • Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

    Silke Walter;Maryse Letiembre;Yang Liu;Holger Heine

  • Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial

    Silke Walter;Panagiotis Kostopoulos;Anton Haass;Isabel Keller

  • Proinflammatory cytokines in serum of patients with acute cerebral ischemia: kinetics of secretion and relation to the extent of brain damage and outcome of disease

    Klaus Fassbender;Siegbert Rossol;Thomas Kammer;Michael Daffertshofer

  • TLR2 Is a Primary Receptor for Alzheimer’s Amyloid β Peptide To Trigger Neuroinflammatory Activation

    Shirong Liu;Yang Liu;Wenlin Hao;Lisa Wolf

  • LPS receptor (CD14): a receptor for phagocytosis of Alzheimer’s amyloid peptide

    Yang Liu;Silke Walter;Massimiliano Stagi;Dmitry Cherny

  • The LPS receptor (CD14) links innate immunity with Alzheimer's disease.

    K. Fassbender;S. Walter;S. Kühl;S. Kühl;R. Landmann

  • Inflammatory cytokines in subarachnoid haemorrhage: association with abnormal blood flow velocities in basal cerebral arteries.

    K Fassbender;B Hodapp;S Rossol;T Bertsch

  • Streamlining of prehospital stroke management: the golden hour.

    Klaus Fassbender;Clotilde Balucani;Silke Walter;Steven R Levine

  • Stent-Assisted Mechanical Recanalization for Treatment of Acute Intracerebral Artery Occlusions

    C. Roth;P. Papanagiotou;S. Behnke;S. Walter

  • Screening of innate immune receptors in neurodegenerative diseases: a similar pattern.

    Maryse Letiembre;Yang Liu;Silke Walter;Wenlin Hao

  • Pattern of activation of the hypothalamic-pituitary-adrenal axis in acute stroke. Relation to acute confusional state, extent of brain damage, and clinical outcome.

    K Fassbender;R Schmidt;R Mössner;M Daffertshofer

  • Mood disorders and dysfunction of the hypothalamic-pituitary-adrenal axis in multiple sclerosis : Association with cerebral inflammation

    Klaus Fassbender;Roland Schmidt;Reinald Mößner;Udo Kischka

  • Circulating Selectin- and Immunoglobulin-Type Adhesion Molecules in Acute Ischemic Stroke

    Klaus Fassbender;Rainald Mössner;Lilian Motsch;Udo Kischka

  • Leakage of brain-originated proteins in peripheral blood: temporal profile and diagnostic value in early ischemic stroke

    Klaus Fassbender;Roland Schmidt;Andreas Schreiner;Mark Fatar

  • 24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

    Hilkka Soininen;Alina Solomon;Alina Solomon;Alina Solomon;Pieter Jelle Visser;Pieter Jelle Visser;Suzanne B Hendrix

  • Innate immune receptor expression in normal brain aging

    M. Letiembre;W. Hao;Y. Liu;S. Walter

  • e-ASPECTS software is non-inferior to neuroradiologists in applying the ASPECT score to computed tomography scans of acute ischemic stroke patients.

    Simon Nagel;Devesh Sinha;Diana Day;Wolfgang Reith

  • Mobile stroke units for prehospital thrombolysis, triage, and beyond: benefits and challenges

    Klaus Fassbender;James C Grotta;Silke Walter;Iris Q Grunwald;Iris Q Grunwald

  • Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain

    Qiaoli Ma;Miriam Ries;Yann Decker;Andreas Müller

  • Endothelin-1 in Subarachnoid Hemorrhage An Acute-Phase Reactant Produced by Cerebrospinal Fluid Leukocytes

    Klaus Fassbender;Britta Hodapp;Siegbert Rossol;Thomas Bertsch

  • Enlarged substantia nigra hyperechogenicity and risk for Parkinson disease: a 37-month 3-center study of 1847 older persons.

    Daniela Berg;Klaus Seppi;Stefanie Behnke;Inga Liepelt

Frequent Co-Authors

Matthias L. Schroeter
Matthias L. Schroeter Max Planck Society
Jan Kassubek
Jan Kassubek University of Ulm
Karsten Mueller
Karsten Mueller Max Planck Society
Francesco Brigo
Francesco Brigo University of Verona
Raffaele Nardone
Raffaele Nardone Paracelsus Medical University
Robert Jech
Robert Jech Czech Education and Scientific Net work
Hans-Jürgen Huppertz
Hans-Jürgen Huppertz Swiss Epilepsy Center
Alessandro Padovani
Alessandro Padovani University of Brescia
Wolfram Ziegler
Wolfram Ziegler Ludwig-Maximilians-Universität München
Daniela Berg
Daniela Berg University Hospital Schleswig-Holstein

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