John M. Nicholls

Overview

Best Publications

• Coronavirus as a possible cause of severe acute respiratory syndrome

  Jsm Peiris;ST Lai;Llm Poon;Y Guan

  4248
  Citations

• Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

  Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami

  1576
  Citations

• Pathogenesis and transmission of SARS-CoV-2 in golden hamsters.

  Sin Fun Sia;Li Meng Yan;Alex W.H. Chin;Kevin Fung

  1459
  Citations

• Lung pathology of fatal severe acute respiratory syndrome

  John M. Nicholls;Leo L. M. Poon;Kam C. Lee;Wai F. Ng

  1412
  Citations

• SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo

  Unknown

  1373
  Citations

• Unravelling the Role of O-glycans in Influenza A Virus Infection

  Juliane Mayr;Kam Lau;Jimmy C. C. Lai;Ivan A. Gagarinov

  1257
  Citations

• Re-emergence of fatal human influenza A subtype H5N1 disease

  J S M Peiris;W C Yu;C W Leung;C Y Cheung

  1164
  Citations

• Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells

  M C W Chan;C Y Cheung;W H Chui;S W Tsao

  698
  Citations

• The M, E, and N Structural Proteins of the Severe Acute Respiratory Syndrome Coronavirus Are Required for Efficient Assembly, Trafficking, and Release of Virus-Like Particles

  Y. L. Siu;K. T. Teoh;J. Lo;C. M. Chan

  568
  Citations

• Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells.

  Helen K. W. Law;Chung Yan Cheung;Hoi Yee Ng;Sin Fun Sia

  542
  Citations

• Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures.

  Kenrie P.Y. Hui;Man Chun Cheung;Ranawaka A.P.M. Perera;Ka Chun Ng

  535
  Citations

• Sialic acid receptor detection in the human respiratory tract: evidence for widespread distribution of potential binding sites for human and avian influenza viruses

  John M Nicholls;Anthony J Bourne;Honglin Chen;Yi Guan

  418
  Citations

• Tropism of avian influenza A (H5N1) in the upper and lower respiratory tract.

  J M Nicholls;M C W Chan;W Y Chan;H K Wong

  418
  Citations

• Influenza A H5N1 replication sites in humans.

  Mongkol Uiprasertkul;Pilaipan Puthavathana;Kantima Sangsiriwut;Phisanu Pooruk

  378
  Citations

• Identification of novel Epstein-Barr virus microRNA genes from nasopharyngeal carcinomas.

  Jia Yun Zhu;Thorsten Pfuhl;Natalie Motsch;Stephanie Barth

  317
  Citations

• Innate immune responses to influenza A H5N1: friend or foe?

  Joseph Sriyal Malik Peiris;Chung Yan Cheung;Connie Yin Hung Leung;John Malcolm Nicholls

  293
  Citations

• High level expression of ΔN-p63: a mechanism for the inactivation of p53 in undifferentiated nasopharyngeal carcinoma (NPC)?

  Tim Crook;John M Nicholls;Louise Brooks;Jenny O'Nions

  280
  Citations

• Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection.

  Trevenan Walther;Rositsa Karamanska;Renee W. Y. Chan;Renee W. Y. Chan;Michael C. W. Chan

  277
  Citations

• Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy

  Daniel T.T Chua;John M Nicholls;Jonathan S.T Sham;Gordon K.H Au

  272
  Citations

• Evolving complexities of influenza virus and its receptors.

  John M. Nicholls;Renee W.Y. Chan;Rupert J. Russell;Gillian M. Air

  272
  Citations

• Identification of cytotoxic T cell epitopes within Epstein‐Barr virus (EBV) oncogene latent membrane protein 1 (LMP1): evidence for HLA A2 supertype‐restricted immune recognition of EBV‐infected cells by LMP1‐specific cytotoxic T lymphocytes

  Rajiv Khanna;Scott R. Burrows;John Nicholls;Leith M. Poulsen

  267
  Citations

• Hemagglutinin–neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets

  Hui-Ling Yen;Chi-Hui Liang;Chung-Yi Wu;Heather L. Forrest

  249
  Citations

• The aetiology, origins, and diagnosis of severe acute respiratory syndrome

  L L M Poon;Y Guan;J M Nicholls;K Y Yuen

  235
  Citations

• Severe Acute Respiratory Syndrome-associated Coronavirus Nucleocapsid Protein Interacts with Smad3 and Modulates Transforming Growth Factor-β Signaling

  Xingang Zhao;John M. Nicholls;Ye-Guang Chen

  235
  Citations

• Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures

  Renee W. Y. Chan;Michael C. W. Chan;Sudhakar Agnihothram;Louisa L. Y. Chan

  214
  Citations

• Replication of avian, human and swine influenza viruses in porcine respiratory explants and association with sialic acid distribution

  Sjouke G M Van Poucke;John M Nicholls;Hans J Nauwynck;Kristien Van Reeth

  212
  Citations

• Comparison of nasopharyngeal flocked swabs and aspirates for rapid diagnosis of respiratory viruses in children.

  K.H. Chan;J.S.M. Peiris;W. Lim;J.M. Nicholls

  211
  Citations

• Viral replication and innate host responses in primary human alveolar epithelial cells and alveolar macrophages infected with influenza H5N1 and H1N1 viruses.

  Wendy C. L. Yu;Renee W. Y. Chan;Jieru Wang;Emily A. Travanty

  208
  Citations