His primary scientific interests are in Virus, Virology, Immunology, Influenza A virus subtype H5N1 and Viral replication. The study incorporates disciplines such as Interferon, Cytotoxic T cell and Glycoprotein in addition to Virus. The various areas that John M. Nicholls examines in his Virology study include Proinflammatory cytokine, Chemokine and Pathogenesis.
The concepts of his Immunology study are interwoven with issues in Lung, Disease and Coronavirus. His Influenza A virus subtype H5N1 research is multidisciplinary, relying on both Sialic acid, Respiratory tract and Cytokine. His biological study spans a wide range of topics, including Neuraminidase, Orthomyxoviridae, Microbiology, H5N1 genetic structure and Pandemic.
The scientist’s investigation covers issues in Virology, Virus, Immunology, Nasopharyngeal carcinoma and Influenza A virus subtype H5N1. His work carried out in the field of Virology brings together such families of science as Ex vivo and Microbiology. Lung is closely connected to Respiratory tract in his research, which is encompassed under the umbrella topic of Virus.
His Nasopharyngeal carcinoma research integrates issues from Cancer research, Carcinoma, Pathology and Epstein–Barr virus. His work deals with themes such as Hemagglutinin and Orthomyxoviridae, which intersect with Influenza A virus subtype H5N1. His Internal medicine research is multidisciplinary, incorporating perspectives in Gastroenterology and Oncology.
John M. Nicholls spends much of his time researching Virology, Virus, Tropism, Influenza A virus subtype H5N1 and Respiratory tract. His Virology study combines topics in areas such as Ex vivo, Coronavirus and Severe acute respiratory syndrome coronavirus 2. His Virus research incorporates themes from Chemokine, Nasopharyngeal carcinoma and Sialic acid.
Influenza A virus subtype H5N1 is the subject of his research, which falls under Immunology. His research integrates issues of Apoptosis, Gene silencing and Cytokine storm in his study of Immunology. His Respiratory tract research is multidisciplinary, incorporating perspectives in Bronchus and Pathogenesis.
John M. Nicholls mostly deals with Virology, Virus, Influenza A virus subtype H5N1, Influenza A virus and Viral replication. The study incorporates disciplines such as Gene silencing, Pathogenesis and Coronavirus in addition to Virology. His studies deal with areas such as Receptor interaction and Cell as well as Virus.
His Influenza A virus subtype H5N1 study is concerned with Immunology in general. John M. Nicholls interconnects In vivo and Alveolar Epithelium in the investigation of issues within Immunology. John M. Nicholls works mostly in the field of Viral replication, limiting it down to topics relating to Ex vivo and, in certain cases, Interferon, Alpha interferon, Disease and Chemokine.
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Coronavirus as a possible cause of severe acute respiratory syndrome
Jsm Peiris;ST Lai;Llm Poon;Y Guan.
The Lancet (2003)
Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury
Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami.
Lung pathology of fatal severe acute respiratory syndrome
John M. Nicholls;Leo L. M. Poon;Kam C. Lee;Wai F. Ng.
The Lancet (2003)
Unravelling the Role of O-glycans in Influenza A Virus Infection
Juliane Mayr;Kam Lau;Jimmy C. C. Lai;Ivan A. Gagarinov.
Scientific Reports (2018)
Re-emergence of fatal human influenza A subtype H5N1 disease
J S M Peiris;W C Yu;C W Leung;C Y Cheung.
The Lancet (2004)
Pathogenesis and transmission of SARS-CoV-2 in golden hamsters.
Sin Fun Sia;Li Meng Yan;Alex W.H. Chin;Kevin Fung.
Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
M C W Chan;C Y Cheung;W H Chui;S W Tsao.
Respiratory Research (2005)
Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells.
Helen K. W. Law;Chung Yan Cheung;Hoi Yee Ng;Sin Fun Sia.
The M, E, and N Structural Proteins of the Severe Acute Respiratory Syndrome Coronavirus Are Required for Efficient Assembly, Trafficking, and Release of Virus-Like Particles
Y. L. Siu;K. T. Teoh;J. Lo;C. M. Chan.
Journal of Virology (2008)
Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures.
Kenrie P.Y. Hui;Man Chun Cheung;Ranawaka A.P.M. Perera;Ka Chun Ng.
The Lancet Respiratory Medicine (2020)
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