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D-Index & Metrics

Chemistry

D-Index
45
Citations
7693
World Ranking
16411
National Ranking
4086

Research.com Recognitions

  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Jean Baum is affiliated with Rutgers, The State University of New Jersey in the United States. Their research spans multiple disciplines within biochemistry, genetics, molecular biology, and medicine. The primary areas of study include molecular biology, neurology, physiology, biomaterials, and infectious diseases.

Baum's main research topics encompass a range of biomedical and molecular subjects, notably:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Collagen: Extraction and Characterization
  • Vaccines and immunoinformatics approaches
  • SARS-CoV-2 and COVID-19 Research
  • RNA regulation and disease
  • Connective tissue disorders research

Recent publications highlight contributions to structural biology, disease mechanism studies, and biomaterials, including:

  • Evolution of the SARS-CoV-2 proteome in three dimensions (3D) during the first 6 months of the COVID-19 pandemic, 2021, Proteins Structure Function and Bioinformatics
  • Molecular dynamics analysis of a flexible loop at the binding interface of the SARS-CoV-2 spike protein receptor-binding domain, 2021, Proteins Structure Function and Bioinformatics
  • Design of synthetic collagens that assemble into supramolecular banded fibers as a functional biomaterial testbed, 2022, Nature Communications
  • Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation, 2020, Frontiers in Bioengineering and Biotechnology
  • Multifaceted interactions mediated by intrinsically disordered regions play key roles in alpha synuclein aggregation, 2023, Current Opinion in Structural Biology

The most frequent co-authors collaborating with Baum include:

  • Jonathan K. Williams
  • Cody L. Hoop
  • Sagar D. Khare
  • Andrew Sam
  • Jennifer Jiang

Baum has published regularly in several scientific venues. The most frequent publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • Zenodo (CERN European Organization for Nuclear Research)
  • Proteins Structure Function and Bioinformatics
  • Protein Science

Jean Baum's work integrates interdisciplinary approaches, linking molecular and structural biology research with clinical relevance in neurodegenerative diseases and infectious disease contexts.

In 1994, Baum was recognized as a Fellow of the Alfred P. Sloan Foundation.

Best Publications

  • Characterization of a partly folded protein by NMR methods: studies on the molten globule state of guinea pig alpha-lactalbumin.

    Jean Baum;Christopher M. Dobson;Philip A. Evans;Philip A. Evans;Claire Hanley

  • Multiple-quantum dynamics in solid state NMR

    J. Baum;M. Munowitz;A. N. Garroway;A. Pines

  • Broadband and adiabatic inversion of a two-level system by phase-modulated pulses.

    J. Baum;R. Tycko;A. Pines

  • Structure and dynamics of the acid-denatured molten globule state of alpha-lactalbumin: a two-dimensional NMR study.

    Andrei T. Alexandrescu;Philip A. Evans;Maureen Pitkeathly;Jean Baum

  • NMR studies of clustering in solids.

    J. Baum;A. Pines

  • Multiple-quantum NMR study of clustering in hydrogenated amorphous silicon.

    J. Baum;K. K. Gleason;A. Pines;A. N. Garroway

  • Structure and stability of the molten globule state of guinea-pig alpha-lactalbumin: a hydrogen exchange study.

    Chia Lin Chyan;Claire Wormald;Christopher M. Dobson;Philip A. Evans

  • N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

    Lijuan Kang;Gina M. Moriarty;Lucy A. Woods;Alison E. Ashcroft

  • Structural reorganization of α-synuclein at low pH observed by NMR and REMD simulations

    Kuen-Phon Wu;Daniel S. Weinstock;Chitra Narayanan;Ronald M. Levy

  • Characterization of collagen-like peptides containing interruptions in the repeating Gly-X-Y sequence

    Cynthia Gwynne Long;Emory Braswell;Dan Zhu;Josefa Apigo

  • Two-dimensional NMR assignments and conformation of (Pro-Hyp-Gly)10 and a designed collagen triple-helical peptide.

    Ming Hua Li;Pei Fan;Barbara Brodsky;Jean Baum

  • Folding of peptide models of collagen and misfolding in disease

    Jean Baum;Barbara Brodsky

  • Structural characterization of monellin in the alcohol-denatured state by NMR: evidence for beta-sheet to alpha-helix conversion.

    Pei Fan;Clay Bracken;Jean Baum

  • Solution structure of a de novo protein from a designed combinatorial library.

    Yinan Wei;Seho Kim;David Fela;Jean Baum

  • Characterization of Conformational and Dynamic Properties of Natively Unfolded Human and Mouse α-Synuclein Ensembles by NMR : Implication for Aggregation

    Kuen-Phon Wu;Seho Kim;David A. Fela;Jean Baum

  • SYNTHESIS AND NUCLEAR MAGNETIC RESONANCE STRUCTURE DETERMINATION OF AN ALPHA -HELICAL, BICYCLIC, LACTAM-BRIDGED HEXAPEPTIDE

    Clay Bracken;Jozsef Gulyas;John W. Taylor;Jean Baum

  • Broadband population inversion by phase modulated pulses

    J. Baum;R. Tycko;A. Pines

  • Backbone dynamics of (Pro-Hyp-Gly)10 and a designed collagen-like triple-helical peptide by 15N NMR relaxation and hydrogen-exchange measurements

    Pei Fan;Ming Hua Li;Barbara Brodsky;Jean Baum

  • Detection of Transient Interchain Interactions in the Intrinsically Disordered Protein α-Synuclein by NMR Paramagnetic Relaxation Enhancement

    Kuen Phon Wu;Jean Baum

  • NMR imaging in solids by multiple-quantum resonance

    A.N Garroway;J Baum;M.G Munowitz;A Pines

Frequent Co-Authors

Barbara Brodsky
Barbara Brodsky Tufts University
Alexander Pines
Alexander Pines University of California, Berkeley
Ronald M. Levy
Ronald M. Levy Temple University
David A. Case
David A. Case Rutgers, The State University of New Jersey
Sheena E. Radford
Sheena E. Radford University of Leeds
Christopher M. Dobson
Christopher M. Dobson University of Cambridge
Masayori Inouye
Masayori Inouye Rutgers, The State University of New Jersey
Michael H. Hecht
Michael H. Hecht Princeton University
M. Maral Mouradian
M. Maral Mouradian Rutgers, The State University of New Jersey
Kathryn E. Uhrich
Kathryn E. Uhrich University of California, Riverside

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