His main research concerns Molecular biology, Biochemistry, Transferrin receptor, Monoclonal antibody and Internalization. Glycoprotein is the focus of his Molecular biology research. His study focuses on the intersection of Biochemistry and fields such as T-cell receptor with connections in the field of Immunoprecipitation, Protein subunit, Molecular mass, Tyrosine phosphorylation and Receptor tyrosine kinase.
His Transferrin receptor study is concerned with Transferrin in general. In his study, which falls under the umbrella issue of Monoclonal antibody, In vitro, Bone marrow and Cell is strongly linked to Antigen. The study incorporates disciplines such as Cytoplasm, Cell biology, Endocytosis and Transplantation in addition to Internalization.
Ian S. Trowbridge spends much of his time researching Molecular biology, Transferrin receptor, Biochemistry, Monoclonal antibody and Antibody. His Molecular biology research incorporates elements of Cell culture, Cytotoxic T cell, Cell and Antigen. His Transferrin receptor research is multidisciplinary, relying on both In vivo and Cell biology.
The various areas that Ian S. Trowbridge examines in his Cell biology study include Endocytic cycle and Internalization. His research in Monoclonal antibody intersects with topics in In vitro, RNA splicing, Cell growth and Immunoprecipitation. In his research, Culture growth is intimately related to Spleen, which falls under the overarching field of Antibody.
His primary scientific interests are in Cell biology, Transferrin receptor, Endocytosis, Internalization and Biochemistry. The concepts of his Cell biology study are interwoven with issues in Endocytic cycle and Receptor, Polymeric immunoglobulin receptor. His Transferrin receptor study combines topics from a wide range of disciplines, such as Molecular biology, Cell culture, Antibody and Cell growth.
His Molecular biology research is multidisciplinary, incorporating elements of MHC restriction, Monoclonal antibody and Antigen-presenting cell. The study incorporates disciplines such as Molecular mass, Halogenation, Antigen and Polyacrylamide in addition to Antibody. His studies deal with areas such as Cell surface receptor and Transplantation as well as Internalization.
His primary areas of investigation include Cell biology, Endosome, Endocytosis, Endocytic cycle and Clathrin. His Cell biology research is multidisciplinary, incorporating perspectives in Transferrin receptor and Internalization. His study on Transferrin receptor is mostly dedicated to connecting different topics, such as Cytoplasm.
Ian S. Trowbridge has researched Endosome in several fields, including Vesicle and Cell polarity. Endocytic cycle is a subfield of Receptor that he studies. While the research belongs to areas of Clathrin, Ian S. Trowbridge spends his time largely on the problem of Cell membrane, intersecting his research to questions surrounding Transmembrane domain and Bulk movement.
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CD45: An Emerging Role as a Protein Tyrosine Phosphatase Required for Lymphocyte Activation and Development
Ian S. Trowbridge;Matthew L. Thomas.
Annual Review of Immunology (1994)
Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway
I S Trowbridge;J F Collawn;C R Hopkins.
Annual Review of Cell Biology (1993)
Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis
James F. Collawn;Martin Stangel;Leslie A. Kuhn;Victor Esekogwu.
Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines.
Hanne L. Ostergaard;Deborah A. Shackelford;Tamara R. Hurley;Pauline Johnson.
Proceedings of the National Academy of Sciences of the United States of America (1989)
Detection of a novel human class II HLA antigen
Andrew J. Watson;Robert DeMars;Ian S. Trowbridge;Fritz H. Bach.
Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues
Ian S. Trowbridge;Jayne Lesley;Roberta Schulte;Robert Hyman.
Monoclonal antibody to transferrin receptor blocks transferrin binding and inhibits human tumor cell growth in vitro.
Ian S. Trowbridge;Frederick Lopez.
Proceedings of the National Academy of Sciences of the United States of America (1982)
Biosynthesis of the human transferrin receptor in cultured cells.
M B Omary;I S Trowbridge.
Journal of Biological Chemistry (1981)
Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells
Ian S. Trowbridge;Derrick L. Domingo.
Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization.
Shuqian Jing;Terry Spencer;Karen Miller;Colin Hopkins.
Journal of Cell Biology (1990)
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